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About 310 results

ALLMedicine™ Iron Toxicity Center

Research & Reviews  106 results

Reduction of iron toxicity in the heart of iron-overloaded mice with natural compounds.
https://doi.org/10.1016/j.ejphar.2022.174981
European Journal of Pharmacology; Alikhani M, Aalikhani M et. al.

Apr 30th, 2022 - Iron-overload is one of the risk factors in susceptible individuals. Iron-overload causes complications such as diastolic dysfunction, arrhythmias, ventricular dilation, and systolic dysfunction in the heart. Therefore, particular care is needed f...

Preoperative Monoferric for Abdominal Surgery
https://clinicaltrials.gov/ct2/show/NCT05258825

Apr 21st, 2022 - The Food and Drug Administration approved drug Monoferric has a unique structure that allows for a slow, sustained release and bioavailability without free iron toxicity. Efficacy studies demonstrated a faster change in hemoglobin concentration fr...

The Iron Content of Ferritin in Serum and Urine of Children With High Serum Ferritin Levels
https://clinicaltrials.gov/ct2/show/NCT03777904

Apr 5th, 2022 - A serum ferritin level can reflect the total body iron content, thus a very low serum ferritin is commonly used as an indicator of iron deficiency and a very high serum ferritin is commonly used as a marker of iron overload. Ferritin is a shell of...

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients
https://clinicaltrials.gov/ct2/show/NCT05255445

Mar 21st, 2022 - Sickle cell disease (SCD) and thalassemia are genetic disorders inducing anemia of differing pathophysiology. A primary therapy for preventing certain SCD complications (e.g., stroke) and for thalassemia major is regular red blood cell (RBC) trans...

Porphyromonas gingivalis outer membrane vesicles as the major drivers of and source for...
https://doi.org/10.1002/alz.056458
Alzheimer's & Dementia : the Journal of the Alzheimer's A... Nara PL

Feb 4th, 2022 - Alzheimer's disease (AD) is a progressive neuroinflammatory and neurodegenerative disease of the brain, defined by the accumulation and deposition of beta-amyloid, which has recently been identified as an antimicrobial peptide suggesting an infect...

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Clinicaltrials.gov  15 results

Preoperative Monoferric for Abdominal Surgery
https://clinicaltrials.gov/ct2/show/NCT05258825

Apr 21st, 2022 - The Food and Drug Administration approved drug Monoferric has a unique structure that allows for a slow, sustained release and bioavailability without free iron toxicity. Efficacy studies demonstrated a faster change in hemoglobin concentration fr...

The Iron Content of Ferritin in Serum and Urine of Children With High Serum Ferritin Levels
https://clinicaltrials.gov/ct2/show/NCT03777904

Apr 5th, 2022 - A serum ferritin level can reflect the total body iron content, thus a very low serum ferritin is commonly used as an indicator of iron deficiency and a very high serum ferritin is commonly used as a marker of iron overload. Ferritin is a shell of...

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients
https://clinicaltrials.gov/ct2/show/NCT05255445

Mar 21st, 2022 - Sickle cell disease (SCD) and thalassemia are genetic disorders inducing anemia of differing pathophysiology. A primary therapy for preventing certain SCD complications (e.g., stroke) and for thalassemia major is regular red blood cell (RBC) trans...

Clinical Assessment of Oral Lactoferrin as a Safe Antiviral and Immunoregulatory in Treating COVID-19 Disease
https://clinicaltrials.gov/ct2/show/NCT04412395

Nov 15th, 2021 - The World Health Organization (WHO) declared the coronavirus (SARS-CoV-2, COVID-19) outbreak a Public Health Emergency of International Concern with a pandemic spread. The situation is rapidly evolving, which raises the approach of reproposing alr...

Brain Iron Toxicity and Neurodegeneration - A 7T MRI Study
https://clinicaltrials.gov/ct2/show/NCT04992975

Aug 6th, 2021 - This study aims to determine whether high resolution MRI at 7T and Quantitative Susceptibility Mapping (QSM) can demonstrate a specific pattern of iron overload in strategically important areas of brain as a sensitive marker of pathological Alzhei...

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News  3 results

Will We Make Artificial Blood Soon? (STAT)
https://www.medpagetoday.com/criticalcare/intensivists/63444

Feb 27th, 2017 - Researchers have sought a blood substitute for over 150 years, and they've all failed. Now, one candidate has demonstrated promising early results, while another nears clinical trials again, reported STAT. ErythroMer encloses hemoglobin in a synth...

Study challenges previous notions about RBC disposal
https://www.mdedge.com/hematology-oncology/article/187203/anemia/study-challenges-previous-notions-about-rbc-disposal
HT Staff

Jul 19th, 2016 - Red blood cells A new study contradicts previous beliefs about how the body disposes of red blood cells (RBCs) and recycles their iron. The work suggests the accumulation and removal of aged or damaged RBCs largely takes place in the liver rather.

Excess Iron May Boost Adult Height
https://www.medpagetoday.com/hematologyoncology/hematology/41120

Aug 21st, 2013 - Action Points Patients with hemochromatosis were taller on average than those in a reference population. The deviation in height did not correlate with the type of HFE mutation, serum ferritin level, liver enzyme elevation, liver fibrosis, or clin...

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