ALLMedicine™ Lithium Toxicity Center

May 10th, 2022 - Lithium is a psychotropic drug used primarily in the treatment of bipolar disorder. It is renally excreted and characteristically causes nephrogenic diabetes insipidus as an adverse drug reaction. Lithium also requires serum level monitoring as th...

Apr 19th, 2022 - Bipolar disorder is a chronic psychological disorder and lithium remains the mainstay of therapy. Lithium toxicity can be acute or chronic and the effects may be disabling or life-threatening. The presence of risk factors can increase the chances ...

Mar 16th, 2022 - Extracorporeal Treatment (ECTR) is an essential component in management of severe lithium toxicity. The Extracorporeal Treatments in Poisoning (EXTRIP) group's suggested indications for ECTR include "if the expected time to obtain a [Li+] < 1.0mEq...

Feb 11th, 2022 - Approach Considerations A number of reasons exist for obtaining selected laboratory studies in patients with bipolar disorder, or manic-depressive illness (MDI). An extensive range of tests is indicated, because bipolar disorder encompasses both d...

Jan 18th, 2022 - Medication Summary Diuretics and nonsteroidal anti-inflammatory drugs (NSAIDs) are used in the treatment of stable lithium-induced nephrogenic diabetes insipidus. [37] Next: Diuretics Class Summary Decrease extracellular fluid and promote proximal...

May 9th, 2022 - BOXED WARNING SECTION When pregnancy is detected, discontinue amlodipine and valsartan tablets as soon as possible. (5.1) Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. (5.1) WARNING: FE...

Apr 15th, 2022 - SPL product data elements section ani SPL UNCLASSIFIED SECTION Rx only Boxed Warning section Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. Facilities for prompt and accurate se...

Mar 10th, 2022 - SPL product data elements section ani SPL UNCLASSIFIED SECTION Rx only Boxed Warning section Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. Facilities for prompt and accurate se...

Feb 24th, 2022 - WARNINGS AND PRECAUTIONS SECTION Furosemide Tablets, USP Rx only WARNING FUROSEMIDE TABLETS is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical...

Feb 17th, 2022 - BOXED WARNING SECTION Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may...

May 30th, 2018 - Diabetes insipidus is defined as the passage of large volumes of dilute urine. It has two major forms: central and nephrogenic. Central diabetes insipidus is characterized by decreased secretion of antidiuretic hormone (ADH), which gives rise to p...

May 30th, 2018 - Diabetes insipidus is defined as the passage of large volumes of dilute urine. It has two major forms: central and nephrogenic. Central diabetes insipidus is characterized by decreased secretion of antidiuretic hormone (ADH), which gives rise to p...

Nov 1st, 2017 - Mr. C, age 30, with schizoaffective disorder, bipolar type, Cannabis abuse, and nicotine dependence, has been enrolled in a Program of Assertive Community Treatment (PACT) for approximately 5 years.

Jun 16th, 2017 - Lithium's Safety Profile Dana Wang, MD, a senior resident in the Harvard South Shore program, reviewed the kidney effects of lithium and the latest studies quantifying those harms. For instance, in recent data from Sweden, lithium was associated w...

Jan 19th, 2012 - This study was funded by the National Institute for Health Research Programme Grant for Applied Research. The authors had no disclosures to report.