ALLMedicine™ Addison Disease Center

Dec 7th, 2020 - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) (polyglandular endocrinopathy type 1) is a rare autosomal recessive disorder caused by mutations in the autoimmune regulator gene (AIRE). The major clinical features of APECED...

Oct 17th, 2020 - BACKGROUND Autoimmune polyglandular syndrome type 1 (APS-1) is an extremely rare autoimmune disorder with an autosomal recessive inheritance pattern. Its manifestations present in chronological sequence of the components mucocutaneous candidiasis,...

May 19th, 2020 - Appropriate management of adrenal insufficiency (AI) in pregnancy can be challenging due to the rarity of the disease and lack of evidence-based recommendations to guide glucocorticoid and mineralocorticoid dosage adjustment. Multicenter survey on...

May 11th, 2020 - Contrary to current dogma, growing evidence suggests that some patients with autoimmune Addison disease (AAD) produce corticosteroids even years after diagnosis. To determine frequencies and clinical features of residual corticosteroid production ...

Apr 17th, 2020 - The natural history of adrenal function in autoimmune Addison disease once diagnosed and treated has not been systematically studied, but several case reports of recovery from established adrenal failure suggest it may not be uniform. To ascertain...

Jan 31st, 2014 - Primary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal cortex.

Dec 7th, 2020 - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) (polyglandular endocrinopathy type 1) is a rare autosomal recessive disorder caused by mutations in the autoimmune regulator gene (AIRE). The major clinical features of APECED...

Oct 17th, 2020 - BACKGROUND Autoimmune polyglandular syndrome type 1 (APS-1) is an extremely rare autoimmune disorder with an autosomal recessive inheritance pattern. Its manifestations present in chronological sequence of the components mucocutaneous candidiasis,...

May 19th, 2020 - Appropriate management of adrenal insufficiency (AI) in pregnancy can be challenging due to the rarity of the disease and lack of evidence-based recommendations to guide glucocorticoid and mineralocorticoid dosage adjustment. Multicenter survey on...

May 11th, 2020 - Contrary to current dogma, growing evidence suggests that some patients with autoimmune Addison disease (AAD) produce corticosteroids even years after diagnosis. To determine frequencies and clinical features of residual corticosteroid production ...

Apr 17th, 2020 - The natural history of adrenal function in autoimmune Addison disease once diagnosed and treated has not been systematically studied, but several case reports of recovery from established adrenal failure suggest it may not be uniform. To ascertain...

Aug 3rd, 2010 - Discussion Addison disease is a disorder of the adrenal glands that results in decreased production of steroids. It was first described by British physician Thomas Addison in 1855. The incidence of Addison disease is 40-60 cases per million, and t...

Aug 3rd, 2010 - Case Summary This patient's presentation to the ED can be concisely summarized to contribute to the diagnosis of Addison disease with adrenal crisis: weakness, vomiting, abdominal pain, abnormal skin and mucous membrane coloring, hypotension, tach...

Cutaneous pigmentation is a hallmark of Addison disease. When present, the hyperpigmentation generally localizes to sun-exposed surfaces.