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About 485 results

ALLMedicine™ Adrenal Crisis Center

Research & Reviews  163 results

Adrenal crisis and mortality rate in adrenal insufficiency and congenital adrenal hyper...
https://doi.org/10.20945/2359-3997000000392
Archives of Endocrinology and Metabolism; Lousada LM, Mendonca BB et. al.

Jul 21st, 2021 - Primary adrenal insufficiency (PAI) is characterized by the inability of the adrenal cortex to produce sufficient amounts of glucocorticoids and/or mineralocorticoids. Addison's disease (AD) and congenital adrenal hyperplasia (CAH) are the most fr...

A Novel Intronic Splice-Site Mutation of the CYP11A1 Gene Linked to Adrenal Insufficien...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295740
International Journal of Environmental Research and Publi... Matusik P, Gach A et. al.

Jul 21st, 2021 - A novel CYP11A1: c.1236 + 5G > A was identified, expanding the mutation spectrum of the congenital adrenal insufficiency with 46,XY sex reversal. In a now 17-year-old girl delivered full-term (G2P2, parents unrelated), adrenal failure was diagnose...

Silent, isolated ACTH deficiency in malignant melanoma patients treated with immune che...
https://doi.org/10.1136/bcr-2021-241981
BMJ Case Reports; Heck A, Winge-Main AK

May 29th, 2021 - Treatment with immune checkpoint inhibitors (ICI) has drastically improved the prognosis for melanoma patients, but immune-mediated adverse events can occur in any organ, including the pituitary. In ICI-induced hypophysitis, lymphocytic infiltrati...

A 45-year-old female patient with Sheehan's syndrome presenting with imminent adrenal c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105925
Journal of Medical Case Reports; Genetu A, Anemen Y et. al.

May 9th, 2021 - Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis. We describe the case of a 45-year-...

Death Due to Adrenal Crisis: Case Report and a Review of the Forensic Literature.
https://doi.org/10.1097/PAF.0000000000000678
The American Journal of Forensic Medicine and Pathology; Gitto L, Stoppacher R et. al.

Apr 10th, 2021 - Adrenal crisis is a life-threatening manifestation of acute adrenal insufficiency. One of the most important underlying causes is Addison disease (primary adrenal insufficiency).A 42-year-old White woman with a medical history of Addison disease o...

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Guidelines  1 results

Management of immune-related adverse events in endocrine organs induced by immune check...
https://doi.org/10.1507/endocrj.EJ19-0163
Endocrine Journal; Arima H, Iwama S et. al.

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

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Clinicaltrials.gov  3 results

Rheumatoid Arthritis Adrenal Recovery Study
https://clinicaltrials.gov/ct2/show/NCT03294876

Oct 11th, 2018 - Cortisol is a naturally occurring stress hormone. It is made by the adrenal glands in response to hormones produced by the pituitary and hypothalamus. Man-made forms of cortisol ('steroids', for example prednisolone) have been used for the treatme...

Optimising Steroid Replacement in Patients With Adrenal Insufficiency
https://clinicaltrials.gov/ct2/show/NCT03282487

Sep 14th, 2017 - This is a prospective, cross-over study. This study cannot be blinded or placebo controlled due to the risk of adrenal crisis in the study population with primary and secondary adrenal insufficiency. The aim of study is to assess the effect of imm...

Survey in Patients With Chronic Adrenal Insufficiency in Germany
https://clinicaltrials.gov/ct2/show/NCT00444119

Mar 7th, 2007 - The purpose of this survey is to assess patients with chronic primary or secondary adrenal failure regarding subjective health status, incidence and causes of adrenal crisis, hormone replacement regimens and concomitant endocrine or non endocrine ...

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News  25 results

Drug Safety Update on Hydrocortisone Granules in Young Children
https://www.medscape.com/viewarticle/946284

Feb 23rd, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on Alkindi (hydrocortisone granules, Diurnal), after a report of severe adrenal insufficiency in an infant who was switched from hydrocortisone soluble ...

AS After GC Common, Persistent in Children With Rheumatic Disease
https://www.medpagetoday.com/rheumatology/arthritis/60986

Oct 24th, 2016 - Action Points Adrenal suppression (AS) following glucocorticoid (GC) therapy in children with rheumatic diseases is common and persistent. Note that some individuals with AS can experience biochemical changes without exhibiting symptoms, leading t...

Medical Mimics of Psychiatric Conditions, Part 2
https://www.mdedge.com/emergencymedicine/article/109397/endocrinology/medical-mimics-psychiatric-conditions-part-2/page/0/2

Jun 3rd, 2016 - Steroid Dysregulation Steroid dysregulation, either endogenous or iatrogenic in nature, has been reported to cause neuropsychiatric symptoms. Major depression with psychotic features can be an initial presentation of Cushing disease, especially in.

Endocrine Society Publishes Clinical Practice Guideline on Addison’s Disease
https://www.mdedge.com/endocrinology/article/107308/rare-diseases/endocrine-society-publishes-clinical-practice-guideline

Mar 11th, 2016 - The Endocrine Society guidelines for diagnosis and treatment of primary adrenal insufficiency recommend that acutely ill patients with unexplained symptoms have diagnostic testing to rule out primary adrenal insufficiency, those who have severe sy.

New PAI Guidelines Stress Importance of Treating Adrenal Crisis
https://www.medscape.com/viewarticle/857554

Jan 21st, 2016 - The first-ever guidelines from the Endocrine Society on diagnosis and management of primary adrenal insufficiency (PAI) call for the use of the high-dose corticotropin stimulatory test as the gold standard for diagnosis in adults, hydrocortisone a...

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Patient Education  2 results see all →