ALLMedicine™ Cushing Syndrome Center

Apr 8th, 2021 - To gain more insight on the pathogenesis of somatotroph pituitary adenomas, recent studies have focused on a subgroup of patients with acromegaly displaying a paradoxical growth hormone (GH) response during oral glucose tolerance test (OGTT). The ...

Mar 8th, 2021 - We present a case report of a 62-year old female with HIV and chronic facetogenic back pain who underwent bilateral L3-L4 and L4-L5 medial branch nerve blocks using triamcinolone acetonide 80 mg. 2 weeks later she presented to the emergency depart...

Feb 25th, 2021 - Pathogenic variants in KCNJ5, encoding the GIRK4 (Kir3.4) potassium channel, have been implicated in the pahogenesis of familial hyperaldosteronism (FH) type-III (FH-III) and sporadic primary hyperaldosteronism (PA). In addition to aldosterone, gl...

Feb 16th, 2021 - In this review, we provide a comprehensive overview of the utility of steroid profiling for diagnosis of management of overt Cushing syndrome and mild autonomous cortisol secretion. A diagnosis of Cushing syndrome is made through a multistep proce...

Feb 12th, 2021 - The authors present a rare case of multiple vertebral compression fractures in a young female with iatrogenic glucocorticoid-induced Cushing syndrome and concomitant human immunodeficiency virus (HIV) infection. Both long-term steroid use and HIV ...

Jul 31st, 2019 - Hirsutism is the excessive growth of terminal hair in a typical male pattern in a female. It is often a sign of excessive androgen levels. Although many conditions can lead to hirsutism, polycystic ovary syndrome and idiopathic hyperandrogenism ac...

Jul 31st, 2015 - Treatment of Cushing's syndrome is essential to reduce mortality and associated comorbidities. Effective treatment includes the normalization of cortisol levels or action.

Apr 13th, 2021 - Excess mortality among people with endogenous Cushing syndrome (CS) has declined in the past 20 years yet remains three times higher than in the general population, new research finds. Among more than 90,000 individuals with endogenous CS, the ove...

Apr 8th, 2021 - To gain more insight on the pathogenesis of somatotroph pituitary adenomas, recent studies have focused on a subgroup of patients with acromegaly displaying a paradoxical growth hormone (GH) response during oral glucose tolerance test (OGTT). The ...

Mar 8th, 2021 - We present a case report of a 62-year old female with HIV and chronic facetogenic back pain who underwent bilateral L3-L4 and L4-L5 medial branch nerve blocks using triamcinolone acetonide 80 mg. 2 weeks later she presented to the emergency depart...

Feb 25th, 2021 - Pathogenic variants in KCNJ5, encoding the GIRK4 (Kir3.4) potassium channel, have been implicated in the pahogenesis of familial hyperaldosteronism (FH) type-III (FH-III) and sporadic primary hyperaldosteronism (PA). In addition to aldosterone, gl...

Feb 16th, 2021 - In this review, we provide a comprehensive overview of the utility of steroid profiling for diagnosis of management of overt Cushing syndrome and mild autonomous cortisol secretion. A diagnosis of Cushing syndrome is made through a multistep proce...

Apr 13th, 2021 - Excess mortality among people with endogenous Cushing syndrome (CS) has declined in the past 20 years yet remains three times higher than in the general population, new research finds. Among more than 90,000 individuals with endogenous CS, the ove...

Dec 10th, 2019 - Patients with Cushing syndrome may have weight gain. They also frequently notice changes in their skin, including purple stretch marks, easy bruising, and other signs of skin thinning. They may have difficulty climbing stairs, getting out of a low...

Dec 10th, 2019 - The adrenal glands are a pair of triangular glands, each about 2 inches long and 1 inch wide, that sit on top of the kidneys. They are responsible for the release of hormones that regulate metabolism, immune system function, and the salt-water bal...

Dec 10th, 2019 - The adrenal glands are a pair of triangular glands, each about 2 inches long and 1 inch wide, that sit on top of the kidneys. They are responsible for the release of hormones that regulate metabolism, immune system function, and the salt-water bal...

Nov 14th, 2019 - The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has given a positive opinion for osilodrostat for the treatment of Cushing syndrome in adults. This is effectively the first worldwide marketing autho...