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About 1,820 results

ALLMedicine™ Cushing Syndrome Center

Research & Reviews  889 results

Differential diagnostic value of bilateral inferior Petrosal sinus sampling (BIPSS) in ...
https://doi.org/10.1186/s12902-020-00623-3
BMC Endocrine Disorders; Wang H, Ba Y et. al.

Sep 18th, 2020 - Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome. This meta-analysis evaluated th...

Differences in outcomes of bilateral adrenalectomy in patients with ectopic ACTH produc...
https://doi.org/10.1016/j.amjsurg.2020.08.047
American Journal of Surgery; Szabo Yamashita T, Sada A et. al.

Sep 14th, 2020 - Endogenous Cushing syndrome (CS) can be caused by ectopic corticotropin-producing tumors of known (EK) and unknown origin (EU). Bilateral adrenalectomy (BA) can be used as definite treatment of hypercortisolism in such cases. This study compared p...

Genomic and sequence variants of protein kinase A regulatory subunit type 1β (PRKAR1B) ...
https://doi.org/10.1038/s41436-020-00958-1
Genetics in Medicine : Official Journal of the American College of Medical Genetics; Drougat L, Settas N et. al.

Sep 8th, 2020 - Protein kinase A (PKA) subunit defects (in PRKAR1A and PRKACA) are known to contribute to adrenal tumor pathogenesis. We studied the PRKAR1B gene for any genetic changes in bilateral adrenocortical hyperplasia (BAH) and cortisol-producing adrenal ...

DNA Methylation of steroidogenic enzymes in benign adrenocortical tumors: NEW INSIGHTS ...
https://doi.org/10.1210/clinem/dgaa585
The Journal of Clinical Endocrinology and Metabolism; Di Dalmazi G, Morandi L et. al.

Aug 25th, 2020 - DNA methylation has been identified among putative regulatory mechanisms for CYP11B2 expression in primary aldosteronism. To investigate DNA methylation and expression of genes encoding steroidogenic enzymes in benign adrenocortical tumors. Cross-...

Human Corticotropin-Releasing Hormone Tests: 10 Years of Real-Life Experience in Pituit...
https://doi.org/10.1210/clinem/dgaa564
The Journal of Clinical Endocrinology and Metabolism; Ceccato F, Tizianel I et. al.

Aug 20th, 2020 - The human corticotropin-releasing hormone (CRH) test (hCRHtest) is used to differentiate Cushing disease (CD) from ectopic adrenocorticotropin (ACTH) secretion (EAS), to assess autonomous cortisol secretion by the adrenal glands, and to characteri...

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Guidelines  2 results

Hirsutism in Women
https://www.aafp.org/afp/2019/0801/p168.html

Jul 31st, 2019 - Hirsutism is the excessive growth of terminal hair in a typical male pattern in a female. It is often a sign of excessive androgen levels. Although many conditions can lead to hirsutism, polycystic ovary syndrome and idiopathic hyperandrogenism ac...

Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline
https://academic.oup.com/jcem/article/100/8/2807/2836065
Lynnette K. Nieman

Jul 31st, 2015 - Treatment of Cushing's syndrome is essential to reduce mortality and associated comorbidities. Effective treatment includes the normalization of cortisol levels or action.

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Drugs  2 results see all →

Clinicaltrials.gov  911 results

Differential diagnostic value of bilateral inferior Petrosal sinus sampling (BIPSS) in ...
https://doi.org/10.1186/s12902-020-00623-3
BMC Endocrine Disorders; Wang H, Ba Y et. al.

Sep 18th, 2020 - Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome. This meta-analysis evaluated th...

Differences in outcomes of bilateral adrenalectomy in patients with ectopic ACTH produc...
https://doi.org/10.1016/j.amjsurg.2020.08.047
American Journal of Surgery; Szabo Yamashita T, Sada A et. al.

Sep 14th, 2020 - Endogenous Cushing syndrome (CS) can be caused by ectopic corticotropin-producing tumors of known (EK) and unknown origin (EU). Bilateral adrenalectomy (BA) can be used as definite treatment of hypercortisolism in such cases. This study compared p...

Genomic and sequence variants of protein kinase A regulatory subunit type 1β (PRKAR1B) ...
https://doi.org/10.1038/s41436-020-00958-1
Genetics in Medicine : Official Journal of the American College of Medical Genetics; Drougat L, Settas N et. al.

Sep 8th, 2020 - Protein kinase A (PKA) subunit defects (in PRKAR1A and PRKACA) are known to contribute to adrenal tumor pathogenesis. We studied the PRKAR1B gene for any genetic changes in bilateral adrenocortical hyperplasia (BAH) and cortisol-producing adrenal ...

DNA Methylation of steroidogenic enzymes in benign adrenocortical tumors: NEW INSIGHTS ...
https://doi.org/10.1210/clinem/dgaa585
The Journal of Clinical Endocrinology and Metabolism; Di Dalmazi G, Morandi L et. al.

Aug 25th, 2020 - DNA methylation has been identified among putative regulatory mechanisms for CYP11B2 expression in primary aldosteronism. To investigate DNA methylation and expression of genes encoding steroidogenic enzymes in benign adrenocortical tumors. Cross-...

Human Corticotropin-Releasing Hormone Tests: 10 Years of Real-Life Experience in Pituit...
https://doi.org/10.1210/clinem/dgaa564
The Journal of Clinical Endocrinology and Metabolism; Ceccato F, Tizianel I et. al.

Aug 20th, 2020 - The human corticotropin-releasing hormone (CRH) test (hCRHtest) is used to differentiate Cushing disease (CD) from ectopic adrenocorticotropin (ACTH) secretion (EAS), to assess autonomous cortisol secretion by the adrenal glands, and to characteri...

see more →

News  5 results

Hirsutism in Women
https://www.aafp.org/afp/2019/0801/p168.html

Jul 31st, 2019 - Hirsutism is the excessive growth of terminal hair in a typical male pattern in a female. It is often a sign of excessive androgen levels. Although many conditions can lead to hirsutism, polycystic ovary syndrome and idiopathic hyperandrogenism ac...

A Faster Way to Diagnose Cushing Syndrome
https://www.mdedge.com/fedprac/article/132985/hospital-medicine/faster-way-diagnose-cushing-syndrome

Mar 1st, 2017 - Diagnosing Cushing syndrome (CS) can take 24 hours of complicated and repeated analyses of blood and urine, brain imaging, and tissue samples from sinuses. But that may soon be in the past.

How to Handle "Incidentalomas"
https://www.mdedge.com/clinicianreviews/article/72459/endocrinology/how-handle-incidentalomas/page/0/1

Nov 1st, 2012 - Q: What is the treatment and follow-up? Here is a quick reference guide regarding surgical treatment and medical follow-up and surveillance: • Adrenalectomy (pheochromocytoma, APA, Cushing syndrome): for masses 4 to 6 cm, consider surgery, especia.

Glucocorticoid-induced diabetes and adrenal suppression: How to detect and manage them
https://www.mdedge.com/ccjm/article/95434/diabetes/glucocorticoid-induced-diabetes-and-adrenal-suppression-how-detect-and?channel=133
M. Cecilia Lansang, MD, MPH, Leighanne Kramer Hustak, DNP, BC-FNP, CDE

Nov 1st, 2011 - Glucocorticoids are commonly prescribed by primary care physicians and specialists alike for multiple medical problems, acute as well as chronic. However, these useful drugs have adverse effects on multiple endocrine systems, effects that include.

Evaluating and managing adrenal incidentalomas
https://www.mdedge.com/ccjm/article/94543/imaging/evaluating-and-managing-adrenal-incidentalomas
Thottathil Gopan, MD, Erick Remer, MD et. al.

ABSTRACTAdrenal masses that are found incidentally should be evaluated with both imaging and hormonal studies. The attenuation coefficient on noncontrast computed tomography (CT), expressed in Hounsfield units (HU), is better than tumor size in di.

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Patient Education  11 results see all →