×
About 2,480 results

ALLMedicine™ Primary Aldosteronism Center

Research & Reviews  903 results

Characterization of pendrin in urinary extracellular vesicles in a rat model of aldoste...
https://doi.org/10.1038/s41440-021-00710-5 10.1016/j.jacc.2006.07.059 10.1291/hypres.27.193 10.1161/01.HYP.0000230444.01215.6a 10.1038/s41440-018-0158-6 10.1038/s41440-020-0468-3 10.2215/CJN.05760513 10.1152/physrev.00011.2019 10.1152/physrev.00044.2018 10.1161/01.HYP.0000145863.96091.89 10.1681/ASN.2017030243 10.1161/01.HYP.0000088321.67254.B7 10.1681/ASN.2012080787 10.1073/pnas.1202671109 10.1046/j.1523-1755.2002.00671.x 10.1152/ajprenal.00211.2004 10.1172/JCI65460 10.1161/HYPERTENSIONAHA.116.08519 10.1016/j.kint.2018.05.001 10.1097/MNH.0000000000000669 10.1152/ajprenal.00114.2011 10.1681/ASN.2019080804 10.1016/j.cmet.2013.10.005 10.1016/j.celrep.2018.06.072 10.1111/cge.12789 10.1016/S0021-9258(18)48095-7 10.1073/pnas.0403453101 10.1038/sj.ki.5000273 10.1038/ki.2009.550 10.1038/sj.ki.5001874 10.1097/MNH.0000000000000192 10.1681/ASN.2008040406 10.1681/ASN.2014111137 10.1007/s00424-017-2049-0 10.1172/JCI43124 10.1073/pnas.1817281116 10.1038/ajh.2008.301 10.1073/pnas.141241098 10.1152/ajprenal.00128.2014 10.1152/ajprenal.00242.2019 10.1681/ASN.2015111221 10.1161/HYPERTENSIONAHA.112.198135 10.1038/s41440-019-0244-4 10.1161/HYPERTENSIONAHA.120.16429 10.1530/JOE-16-0669 10.1038/nsmb.3091 10.1007/s00018-014-1585-4 10.1681/ASN.2019050551 10.1016/S0092-8674(01)00241-0 10.1161/CIRCULATIONAHA.115.018526
Hypertension Research : Official Journal of the Japanese ... Ochiai-Homma F, Kuribayashi-Okuma E et. al.

Jul 31st, 2021 - Pendrin is a Cl-/HCO3- exchanger selectively present in the intercalated cells of the kidney. Although experimental studies have demonstrated that pendrin regulates blood pressure downstream of the renin-angiotensin-aldosterone system, its role in...

Aldosterone-producing adenoma-harbouring KCNJ5 mutations is associated with lower preva...
https://doi.org/10.1097/HJH.0000000000002948
Journal of Hypertension; Chen KM, Chang YL et. al.

Jul 28th, 2021 - Aldosterone overproduction and lipid metabolic disturbances between idiopathic hyperaldosteronism (IHA) and unilateral aldosterone-producing adenoma (APA) have been inconsistently linked in patients with primary aldosteronism. Moreover, KCNJ5 muta...

Characterization of Circulating Extracellular Vesicle Surface Antigens in Patients With...
https://doi.org/10.1161/HYPERTENSIONAHA.121.17136
Hypertension (Dallas, Tex. : 1979); Burrello J, Tetti M et. al.

Jul 27th, 2021 - Primary aldosteronism (PA) is characterized by inappropriate aldosterone production. Chronic aldosterone excess has detrimental effects on cardiovascular system, including endothelial dysfunction and vascular inflammation. Circulating extracellula...

Beta-2-Microglobulin is an Independent Risk Factor for Asymptomatic Carotid Atheroscler...
https://doi.org/10.5551/jat.62851
Journal of Atherosclerosis and Thrombosis; Liang S, Li Q et. al.

Jul 27th, 2021 - To identify the association between serum beta-2-microglobulin (B2M) or cystatin C (CysC) and asymptomatic carotid atherosclerosis in patients with primary aldosteronism (PA). In this cross-sectional study, 265 subjects were enrolled, including 83...

A case of primary aldosteronism with a negative aldosterone-to-renin ratio.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299686
BMC Cardiovascular Disorders; Liu F, Wang L et. al.

Jul 24th, 2021 - Primary aldosteronism (PA), as a cause of secondary hypertension, can cause more serious cardiovascular damage than essential hypertension. The aldosterone-to-renin ratio (ARR) is recommended as the most reliable screening method for PA, but ARR s...

see more →

Guidelines  2 results

Guidelines for the diagnosis and treatment of primary aldosteronism--the Japan Endocrin...
https://doi.org/10.1507/endocrj.ej11-0133
Endocrine Journal; Nishikawa T, Omura M et. al.

Aug 11th, 2011 - The Japan Endocrine Society (JES) attempted to develop guidelines for the diagnosis and treatment of primary aldosteronism (PA). The Task Force Committee (TFC) was composed of a chair, selected by the JES, and additional experts. Systematic review...

Case detection, diagnosis, and treatment of patients with primary aldosteronism: an end...
https://doi.org/10.1210/jc.2008-0104
The Journal of Clinical Endocrinology and Metabolism; Funder JW, Carey RM et. al.

Jun 17th, 2008 - Our objective was to develop clinical practice guidelines for the diagnosis and treatment of patients with primary aldosteronism. The Task Force comprised a chair, selected by the Clinical Guidelines Subcommittee (CGS) of The Endocrine Society, si...

see more →

Clinicaltrials.gov  35 results

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
https://clinicaltrials.gov/ct2/show/NCT03374215

May 6th, 2020 - Primary Aldosteronism (PA) is the most common cause of secondary hypertension, accounting for 6-8% of hypertension and 14-25% of resistant hypertension. This prevalence translates to approximately 1 in 30-50 adults or about 4,000,000 Americans wit...

Adrenal Artery Ablation Treats Primary Aldosteronism
https://clinicaltrials.gov/ct2/show/NCT03398785

Jul 8th, 2019 - Primary aldosteronism (PA) is one of the most common cause of endocrine and resistant hypertension. Current studies have shown that the activation of the renin-angiotensin-aldosterone system (RAAS) and the increased sympathetic nerve activity in t...

Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or Fibrillation
https://clinicaltrials.gov/ct2/show/NCT01267747

Jun 7th, 2019 - A previous retrospective study documented a 12-fold increase of the risk of AFF in patients with primary aldosteronism (PA) as compared to subjects with primary (essential) hypertension (Milliez 2005). However, being retrospective this investigati...

Chongqing Primary Aldosteronism Study
https://clinicaltrials.gov/ct2/show/NCT03224312

Jan 31st, 2019 - Primary aldosteronism (PA) is caused by adrenocortical lesions characterized with autonomous secretion of aldosterone. It is a common cause of secondary hypertension and its reported prevalence ranges from 5% to 20% in hypertensive patients. Sever...

Aldosterone Antagonism and Microvascular Function
https://clinicaltrials.gov/ct2/show/NCT01887119

Oct 8th, 2018 - The prevalence of obesity and obesity-related complications is currently taking epidemic proportions. These complications increase the risk of type 2 diabetes and cardiovascular disease, which are important causes of morbidity and mortality worldw...

see more →

News  50 results

Few Adults at Risk for Primary Aldosteronism Get Screened
https://www.medscape.com/viewarticle/948177

Mar 29th, 2021 - NEW YORK (Reuters Health) - Only 3% of adults at high risk for primary aldosteronism (PA) are screened for the condition, according to a study presented at ENDO 2021, the Endocrine Society's annual meeting. "Primary aldosteronism causes persistent...

Will Scans Help Boost Detection of Resistant Hypertension?
https://www.medscape.com/viewarticle/948024

Mar 24th, 2021 - A noninvasive imaging method for identifying whether the source of a patient's primary aldosteronism is from unilateral or bilateral adrenal adenomas worked as well as the standard method, invasive adrenal vein sampling, in a head-to-head comparis...

Far Too Few With Treatment-Resistant Hypertension Get Hormone Test
https://www.medscape.com/viewarticle/943296

Dec 29th, 2020 - Millions of Americans with treatment-resistant hypertension are likely not being tested to determine whether their high blood pressure is driven by primary aldosteronism (PA), despite guidelines that call for such an approach, according to finding...

Adrenal Venous Sampling Not Always Required Before Unilateral Adenoma Treatment
https://www.medscape.com/viewarticle/940852

Nov 16th, 2020 - NEW YORK (Reuters Health) - In patients with primary aldosteronism and clearly visualized unilateral adenomas, confirmatory adrenal venous sampling (AVS) may not be required prior to surgery, researchers say. "It's important to realize that AVS is...

AVS Is a 'Choke Point' for Aldosteronism Assessment in Hypertension
https://www.medscape.com/viewarticle/939025

Oct 13th, 2020 - At a time when new evidence strongly suggests that roughly a fifth of patients with hypertension have primary aldosteronism as the cause, other recent findings suggest that many of these possibly tens of millions of patients with aldosterone-drive...

see more →

Patient Education  2 results see all →