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About 703 results

ALLMedicine™ Adrenal Crisis Center

Research & Reviews  223 results

Intracardiac thrombosis following intravenous zoledronate treatment in a child with ste...
https://doi.org/10.1515/jpem-2022-0475
Journal of Pediatric Endocrinology & Metabolism : JPEM; Case SJ, Moon RJ et. al.

Nov 26th, 2022 - Bisphosphonates are used in childhood osteoporosis but can cause an acute phase reaction (APR) and hypocalcemia. We present a child with cardiac thrombosis following zoledronate, a previously unreported complication. An 11-year-old with Duchenne m...

Approach to the Patient with Adrenal Hemorrhage.
https://doi.org/10.1210/clinem/dgac672
The Journal of Clinical Endocrinology and Metabolism; Elhassan YS, Ronchi CL et. al.

Nov 21st, 2022 - Adrenal hemorrhage is an uncommon underrecognized condition that can be encountered in several clinical contexts. Diagnosing adrenal hemorrhage is challenging due to the non-specific clinical features. Therefore, it remains a diagnosis that is mad...

The management of congenital adrenal hyperplasia during preconception, pregnancy, and p...
https://doi.org/10.1007/s11154-022-09770-5
Reviews in Endocrine & Metabolic Disorders; Maher JY, Gomez-Lobo V et. al.

Nov 19th, 2022 - Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders of steroidogenesis of the adrenal cortex, most commonly due to 21-hydroxylase deficiency caused by mutations in the CYP21A2 gene. Although women with CAH have decreas...

Congenital adrenal hyperplasia in patients with adrenal tumors: a population-based case...
https://doi.org/10.1007/s40618-022-01933-0
Journal of Endocrinological Investigation; Sahlander F, Patrova J et. al.

Oct 22nd, 2022 - Congenital adrenal hyperplasia (CAH) has been associated with adrenal tumors (ATs) but the relationship is still unclear. The aim was to investigate if CAH was more common in patients with adrenal tumors and their characteristics. Using national r...

Adrenal Crisis in Emergency Medicine
https://emedicine.medscape.com/article/765753-overview

Oct 10th, 2022 - Practice Essentials Acute adrenal crisis is a potentially fatal condition resulting from a lack of the adrenal gland hormone cortisol. Adrenal crisis and severe acute adrenocortical insufficiency are often elusive diagnoses that may result in seve...

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Guidelines  2 results

Management of immune-related adverse events in endocrine organs induced by immune check...
https://doi.org/10.1507/endocrj.EJ19-0163
Endocrine Journal; Arima H, Iwama S et. al.

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

Consensus statement on the diagnosis, treatment and follow-up of patients with primary ...
https://doi.org/10.1111/joim.12162
Journal of Internal Medicine; Husebye ES, Allolio B et. al.

Dec 18th, 2013 - Primary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal cortex. Consequently, patients with PAI are at higher risk of de...

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Clinicaltrials.gov  13 results

Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency
https://clinicaltrials.gov/ct2/show/NCT05435781

Jun 28th, 2022 - The study will include patients with PMR/GCA on ongoing prednisolone treatment in a low dose of > 0 mg/day and ≤5mg/day. Eligible patients will undergo a Synacthen® test and 250 patients with a stimulated cortisol level <420 nmol/l (biochemical ad...

Predisposing Factors for the Incidence of Adrenal Crisis
https://clinicaltrials.gov/ct2/show/NCT03410160

Oct 14th, 2019 - Patients with chronic adrenal insufficiency (AI) are at risk of suffering from life-threatening adrenal crisis (AC), despite established hormone replacement therapies and patient education. Recent retrospective analyses observed different risk fac...

Rheumatoid Arthritis Adrenal Recovery Study
https://clinicaltrials.gov/ct2/show/NCT03294876

Oct 11th, 2018 - Cortisol is a naturally occurring stress hormone. It is made by the adrenal glands in response to hormones produced by the pituitary and hypothalamus. Man-made forms of cortisol ('steroids', for example prednisolone) have been used for the treatme...

Study to Investigate Adrenal Crisis (Six-year Follow-up)
https://clinicaltrials.gov/ct2/show/NCT03499990

Apr 18th, 2018 - Despite established hormone replacement therapy, patients with chronic adrenal insufficiency are at risk of suffering from life threatening adrenal crisis with a considerable mortality. A former prospective study revealed a frequency of about 8 ad...

Management of Adrenal Emergency in Germany
https://clinicaltrials.gov/ct2/show/NCT03426332

Feb 8th, 2018 - Despite established hormone replacement therapy, patients with chronic adrenal insufficiency (AI) are at risk of suffering from adrenal crisis (AC). Further data suggests that the management of AC is often problematic and the time to adequate trea...

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News  40 results

Preop TT3 Predicts HPA Axis Recovery After Cushing Surgery
https://www.medscape.com/viewarticle/984629

Nov 28th, 2022 - The study covered in this summary was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaways The hypothalamic-pituitary-adrenal (HPA) axis recovered in nearly three quarters of patients with Cushing disease...

Opioid-Induced Adrenal Insufficiency for the Hospitalist
https://www.medscape.com/viewarticle/961663

Oct 27th, 2021 - Case A 60-year-old woman with metastatic breast cancer using morphine extended release 30 mg twice daily and as-needed oxycodone for cancer-related pain presents with fever, dyspnea, and productive cough for 2 days. She also notes several weeks of...

Immunotherapy Transforms Melanoma Care, But Challenges Remain
https://www.onclive.com/view/immunotherapy-transforms-melanoma-care-but-challenges-remain

Oct 6th, 2021 - Norman E. Sharpless, MD Today, the field of melanoma is virtually unrecognizable from what it was not that long ago, says Norman E. Sharpless, MD. Most of us are old enough to remember a time when there was nothing going on in melanoma, said Sha...

Drug Safety Update on Hydrocortisone Granules in Young Children
https://www.medscape.com/viewarticle/946284

Feb 23rd, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on Alkindi (hydrocortisone granules, Diurnal), after a report of severe adrenal insufficiency in an infant who was switched from hydrocortisone soluble ...

Practical Advice for Immunotherapy Era Emerges From ASCO
https://www.onclive.com/view/practical-advice-for-immunotherapy-era-emerges-from-asco

Dec 20th, 2020 - Jedd D. Wolchok, MD, PhD Three years ago, Jedd D. Wolchok, MD, PhD, sat in the lobby of a Chicago hotel at midnight during the ASCO annual meeting with several of his colleagues and sketched out on a napkin a dream trial that would simultaneously...

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Patient Education  3 results see all →