About 455 results

ALLMedicine™ Adrenal Crisis Center

Research & Reviews  155 results

A Broken Pathway: Understanding Congenital Adrenal Hyperplasia in the Newborn.
Neonatal Network : NN; Allis K

Sep 15th, 2021 - Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder that leads to the partial or complete deficiency of cortisol and aldosterone production from the adrenal glands. The lack of these key hormones can precipitate acute adrenal c...

Safer care for patients with adrenal insufficiency: weighing the evidence, balancing ri...
Clinical Medicine (London, England); Stacey M, Gifford RM et. al.

Sep 12th, 2021 - The National Patient Safety Alert supporting early recognition and treatment of adrenal crisis is a vital new component of care for adults affected by primary adrenal insufficiency. Benefits for patients with secondary and tertiary adrenal insuffi...

The effects of selected inhibitors on human fetal adrenal steroidogenesis differs under...
BMC Medicine; Melau C, Riis ML et. al.

Sep 9th, 2021 - Disordered fetal adrenal steroidogenesis can cause marked clinical effects including virilization of female fetuses. In postnatal life, adrenal disorders can be life-threatening due to the risk of adrenal crisis and must be carefully managed. Howe...

Adrenal crisis and mortality rate in adrenal insufficiency and congenital adrenal hyper...
Archives of Endocrinology and Metabolism; Lousada LM, Mendonca BB et. al.

Jul 21st, 2021 - Primary adrenal insufficiency (PAI) is characterized by the inability of the adrenal cortex to produce sufficient amounts of glucocorticoids and/or mineralocorticoids. Addison's disease (AD) and congenital adrenal hyperplasia (CAH) are the most fr...

A Novel Intronic Splice-Site Mutation of the CYP11A1 Gene Linked to Adrenal Insufficien...
International Journal of Environmental Research and Publi... Matusik P, Gach A et. al.

Jul 21st, 2021 - A novel CYP11A1: c.1236 + 5G > A was identified, expanding the mutation spectrum of the congenital adrenal insufficiency with 46,XY sex reversal. In a now 17-year-old girl delivered full-term (G2P2, parents unrelated), adrenal failure was diagnose...

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Guidelines  1 results

Management of immune-related adverse events in endocrine organs induced by immune check...
Endocrine Journal; Arima H, Iwama S et. al.

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

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News  26 results

Drug Safety Update on Hydrocortisone Granules in Young Children

Feb 23rd, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on Alkindi (hydrocortisone granules, Diurnal), after a report of severe adrenal insufficiency in an infant who was switched from hydrocortisone soluble ...

AS After GC Common, Persistent in Children With Rheumatic Disease

Oct 24th, 2016 - Action Points Adrenal suppression (AS) following glucocorticoid (GC) therapy in children with rheumatic diseases is common and persistent. Note that some individuals with AS can experience biochemical changes without exhibiting symptoms, leading t...

Medical Mimics of Psychiatric Conditions, Part 2

Jun 3rd, 2016 - Steroid Dysregulation Steroid dysregulation, either endogenous or iatrogenic in nature, has been reported to cause neuropsychiatric symptoms. Major depression with psychotic features can be an initial presentation of Cushing disease, especially in.

Darkened skin, vomiting, and salt cravings in a teenager • Dx?
The Journal of Family Practice;

May 31st, 2016 - Acute adrenal insufficiency crisis usually occurs after a prolonged period of nonspecific complaints due to a loss of both glucocorticoids and mineralocorticoids; by the time overt symptoms occur, 90% of the adrenal gland may be destroyed. 3 Patien.

Endocrine Society Publishes Clinical Practice Guideline on Addison’s Disease

Mar 11th, 2016 - The Endocrine Society guidelines for diagnosis and treatment of primary adrenal insufficiency recommend that acutely ill patients with unexplained symptoms have diagnostic testing to rule out primary adrenal insufficiency, those who have severe sy.

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