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ALLMedicine™ Cushing Syndrome Center

Research & Reviews  436 results


May 13th, 2022 - Reference Range The reference range of urinary 17-ketosteroids is as follows [1] : Males: 10-20 mg (34-69 µmol)/24 h Females: 5-15 mg (17-52 µmol)/24 h Next: Interpretation Increases in levels of 24-hour urinary 17-ketosteroids are associated with...

Cushing syndrome due to ectopic ACTH secreting pheochromocytoma.
BMJ Case Reports; Naeem Durrani M, Popal U

May 12th, 2022 - In this case report, we present a case of a woman in her late 30s who presented with bilateral motor weakness, headache, hyperglycaemia and hypertension. Investigations revealed very high 24-hour urine cortisol of 90 524, ectopic adrenocorticotrop...

Differences in Regulation of Cortisol Secretion Contribute to Left Ventricular Abnormal...
Hypertension (Dallas, Tex. : 1979); Brosolo G, Catena C et. al.

May 11th, 2022 - Left ventricular (LV) abnormalities were reported in patients with overt and subclinical Cushing syndrome. The aim of this study was to investigate the relationships of daily plasma cortisol profile and cortisol response to an overnight suppressio...

A Two-in-One Tumor in the Adrenal: A Functional Adrenocortical Adenoma with Myelolipoma...
Fetal and Pediatric Pathology; Bhardwaj S, Deshpande RS et. al.

May 11th, 2022 - Adrenocortical adenoma (ADA) and myelolipoma are two common benign neoplasms of the adrenal cortex that have been reported to occur together. A 14-year-old girl presented with the features of ACTH-independent endogenous Cushing syndrome. Abdominal...

Super-selective cavernous sinus and inferior petrosal sinus sampling for Cushing syndro...
Interventional Neuroradiology : Journal of Peritherapeuti... Caton MT, Smith ER et. al.

May 3rd, 2022 - Super-selective cavernous sinus and inferior petrosal sinus sampling for Cushing syndrome: Technique and interpretation.|2022|Caton MT,Smith ER,Baker A,Dowd CF,|

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Drugs  2 results see all →

Clinicaltrials.gov  11 results

Steroid Treatment of Idiopathic Nephrotic Syndrome

Jul 20th, 2021 - Background Idiopathic nephrotic syndrome (INS) is the most frequent glomerular disease in childhood, with an incidence of 2-4 cases per 100,000 children. Currently, all children with INS are treated at onset with steroids. Approximately 80% of cas...

A Prospective Cohort Study for Patients With Adrenal Diseases

Mar 18th, 2020 - The investigators will recruit 150 patients annually for 10 years (adrenal incidentaloma 100 patients, pheochromocytoma 15 patients, primary aldosteronism 25 patients, adrenal cushing syndrome 10 patients, adrenocortical carcinoma 2 patients) and ...

Efficacy of Lower Dose Prednisolone in the Induction of Remission of Lupus Nephritis

Oct 31st, 2019 - Rationale: Lupus nephritis (LN) is a very common complication of systemic lupus erythematosus (SLE). Currently available all guidelines suggest an induction phase with glucocorticoids along with another immunosuppressive agent. However, the basis ...

Retrospective Chart Review Study of Pediatric Patients Treated With Korlym for Cushing Syndrome

Jul 30th, 2019 - This retrospective chart review study seeks to collect data from pediatric patients treated with Korlym (mifepristone) to help provide clinicians with some insight on the potential role of mifepristone in the treatment of pediatric patients with C...

Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma

Apr 4th, 2019 - Objective: To determine the metabolic effects of the adrenalectomy in subclinical Cushing's syndrome of adrenal incidentaloma. Methods: 234 subclinical cushing syndrome and adrenal incidentaloma will be randomly assigned into two groups(e.g adrena...

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News  54 results

Glucocorticoid Abnormalities Boost Infections

May 26th, 2022 - Researchers published the study covered in this summary on medRxiv.org as a preprint that has not yet been peer reviewed. Key Takeaways The newly derived Infections in Patients With Endocrinopathies (ICARO) questionnaire is a patient self-report t...

FDA Approves Levoketoconazole for Cushing Syndrome

Jan 4th, 2022 - The US Food and Drug Administration has approved levoketoconazole (Recorlev, Xeris Biopharma) for the treatment of endogenous hypercortisolemia in adults with Cushing syndrome for whom surgery is not possible or was not curative. Endogenous Cushin...

Benign Adrenal Tumors Linked to Hypertension, Type 2 Diabetes

Jan 3rd, 2022 - In more than 15% of people with benign adrenal tumors, the growths produce clinically relevant levels of serum cortisol that are significantly linked with an increased prevalence of hypertension and, in 5% of those with Cushing syndrome (CS), an i...

Cushing Death Rate 'Unacceptable,' Triple That of General Population

Apr 14th, 2021 - Excess mortality among people with endogenous Cushing syndrome (CS) has declined in the past 20 years yet remains three times higher than in the general population, new research finds. Among more than 90,000 individuals with endogenous CS, the ove...

The Man Behind the Brain: Harvey Cushing's Legacy

Sep 9th, 2020 - A physician is obligated to consider more than a diseased organ, more than even the whole man — he must view the man in his world. –Harvey Williams Cushing A well-known photo of Harvey Cushing, taken by a friend in Switzerland. Source: Wikimedia C...

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Patient Education  9 results see all →