ALLMedicine™ Cushing Syndrome Center

Mar 17th, 2023 - The history and findings in this case are suggestive of small cell carcinoma of the prostate (SCCP). SCCP is a rare and aggressive cancer that comprises 1%–5% of all prostate cancers (if mixed cases with adenocarcinoma are included).

Mar 17th, 2023 - Surgical diseases of the adrenal gland include pheochromocytoma/paraganglioma, primary hyperaldosteronism, Cushing syndrome, and adrenocortical carcinoma. These conditions may be associated with familial syndromes, and genetic testing is available...

Mar 14th, 2023 - Practice Essentials Paraneoplastic syndromes are rare disorders that are triggered by an altered immune system response to a neoplasm. They are defined as clinical syndromes involving nonmetastatic systemic effects that accompany malignant disease...

Mar 14th, 2023 - Practice Essentials Paraneoplastic syndromes are rare disorders that are triggered by an altered immune system response to a neoplasm. They are defined as clinical syndromes involving nonmetastatic systemic effects that accompany malignant disease...

Mar 14th, 2023 - Practice Essentials Paraneoplastic syndromes are rare disorders that are triggered by an altered immune system response to a neoplasm. They are defined as clinical syndromes involving nonmetastatic systemic effects that accompany malignant disease...

Feb 10th, 2023 - Study Description: This protocol aims to evaluate subjects with tumors of the hypothalamic pituitary unit to: identify genetic components of pituitary and hypothalamic oncogenesis, to develop new clinical studies for the recognition and thera...

Feb 8th, 2023 - Objective: Cushing Disease (CD) describes the state of hypercortisolemia secondary to cortisol producing pituitary adenomas. The rarity of the disease (2-5 new cases per million, 1 out of 10 in children) and the subtle initial findings result in p...

Feb 3rd, 2023 - This study is designed to allow continued therapy with relacorilant, a potent, selective glucocorticoid receptor (GR) antagonist in patients who have successfully completed participation of a Corcept-sponsored study of relacorilant (referred to as...

Dec 7th, 2022 - Between 10% and 15% of patients with endogenous hypercortisolism (Cushing syndrome) have ectopic (non-pituitary) production of adrenocorticotropin hormone (ACTH) that causes cortisol excess. In approximately 50% of these patients, the tumoral sour...

Dec 5th, 2022 - This is a pilot study to evaluate feasibility and proof of concept. This is a prospective multicenter cohort study. Two university centers will participate (Sherbrooke and Montreal). Participants will be recruited from post-partum Obstetric Medici...

Mar 17th, 2023 - The history and findings in this case are suggestive of small cell carcinoma of the prostate (SCCP). SCCP is a rare and aggressive cancer that comprises 1%–5% of all prostate cancers (if mixed cases with adenocarcinoma are included).

Jan 19th, 2022 - David Gerber, MD: Let’s continue to the second case because it raises an important point—perhaps the most important point of this entire session. In our second case, a 57-year-old man presents to his primary care physician [PCP]; he is experiencin...

Jan 4th, 2022 - The US Food and Drug Administration has approved levoketoconazole (Recorlev, Xeris Biopharma) for the treatment of endogenous hypercortisolemia in adults with Cushing syndrome for whom surgery is not possible or was not curative. Endogenous Cushin...

Jan 3rd, 2022 - In more than 15% of people with benign adrenal tumors, the growths produce clinically relevant levels of serum cortisol that are significantly linked with an increased prevalence of hypertension and, in 5% of those with Cushing syndrome (CS), an i...

May 24th, 2021 - An increased risk of death was seen with higher levels of autonomous cortisol secretion (ACS), a new study found. In a retrospective cohort of patients with adrenal incidentalomas, plasma cortisol level after a 1-mg dexamethasone suppression test ...