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About 3,565 results

ALLMedicine™ Primary Aldosteronism Center

Research & Reviews  1,258 results

An Abbreviated History of Aldosterone Metabolism, Current and Future Challenges.
https://doi.org/10.1055/a-2054-1062
Experimental and Clinical Endocrinology & Diabetes : Offi... Gomez-Sanchez C, Gomez-Sanchez EP

Mar 15th, 2023 - The initial isolation of adrenal steroids from large quantities of animal adrenals resulted in an amorphous fraction resistant to crystallization and identification that had potent effects on electrolyte transport. Aldosterone was eventually isola...

Preoperative Supine Time for Adrenal Venous Sampling
https://clinicaltrials.gov/ct2/show/NCT05658705

Mar 8th, 2023 - Primary aldosteronism (PA) is the most common form of secondary hypertension, accounting for 5% of hypertensive patients and 17-23% in patients with resistant hypertension. Compared to the primary hypertension, PA is more prone to cause severe org...

Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)
https://clinicaltrials.gov/ct2/show/NCT05757076

Mar 7th, 2023 - The mission of this project is to increase the detection of Primary Aldosteronism (PA), the most common cause of secondary hypertension, which can either be cured surgically or treated with targeted medications. It is caused by the autonomous secr...

A Study of CIN-107 in Adults With Primary Aldosteronism
https://clinicaltrials.gov/ct2/show/NCT04605549

Mar 6th, 2023 - This is a multicenter, open-label study in adult patients with PA to evaluate the effectiveness and safety of CIN-107 after up to 12 weeks of treatment, at doses from 2 to 8 mg per day, for the management of blood pressure in patients with primary...

Superselective adrenal arterial embolization for primary aldosteronism without laterali...
https://doi.org/10.1038/s41440-023-01236-8
Hypertension Research : Official Journal of the Japanese ... Qiu J, Li N et. al.

Mar 4th, 2023 - Superselective adrenal arterial embolization (SAAE) appears to be beneficial in primary aldosteronism (PA) patients with lateralized aldosterone secretion (unilateral PA). As confirmed by adrenal vein sampling (AVS), nearly 40% of PA patients woul...

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Guidelines  2 results

Guidelines for the diagnosis and treatment of primary aldosteronism--the Japan Endocrin...
https://doi.org/10.1507/endocrj.ej11-0133
Endocrine Journal; Nishikawa T, Omura M et. al.

Aug 11th, 2011 - The Japan Endocrine Society (JES) attempted to develop guidelines for the diagnosis and treatment of primary aldosteronism (PA). The Task Force Committee (TFC) was composed of a chair, selected by the JES, and additional experts. Systematic review...

Case detection, diagnosis, and treatment of patients with primary aldosteronism: an end...
https://doi.org/10.1210/jc.2008-0104
The Journal of Clinical Endocrinology and Metabolism; Funder JW, Carey RM et. al.

Jun 17th, 2008 - Our objective was to develop clinical practice guidelines for the diagnosis and treatment of patients with primary aldosteronism. The Task Force comprised a chair, selected by the Clinical Guidelines Subcommittee (CGS) of The Endocrine Society, si...

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Clinicaltrials.gov  94 results

Preoperative Supine Time for Adrenal Venous Sampling
https://clinicaltrials.gov/ct2/show/NCT05658705

Mar 8th, 2023 - Primary aldosteronism (PA) is the most common form of secondary hypertension, accounting for 5% of hypertensive patients and 17-23% in patients with resistant hypertension. Compared to the primary hypertension, PA is more prone to cause severe org...

Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)
https://clinicaltrials.gov/ct2/show/NCT05757076

Mar 7th, 2023 - The mission of this project is to increase the detection of Primary Aldosteronism (PA), the most common cause of secondary hypertension, which can either be cured surgically or treated with targeted medications. It is caused by the autonomous secr...

A Study of CIN-107 in Adults With Primary Aldosteronism
https://clinicaltrials.gov/ct2/show/NCT04605549

Mar 6th, 2023 - This is a multicenter, open-label study in adult patients with PA to evaluate the effectiveness and safety of CIN-107 after up to 12 weeks of treatment, at doses from 2 to 8 mg per day, for the management of blood pressure in patients with primary...

Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity
https://clinicaltrials.gov/ct2/show/NCT04519164

Mar 2nd, 2023 - Obesity is a dominant risk factor for the development of cardiovascular disease (CVD). The public health relevance of this relationship is underscored by the fact that 40% (93 million) of adult Americans are obese. Activation of the mineralocortic...

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
https://clinicaltrials.gov/ct2/show/NCT03374215

Feb 28th, 2023 - Primary Aldosteronism (PA) is the most common cause of secondary hypertension, accounting for 6-8% of hypertension and 14-25% of resistant hypertension. This prevalence translates to approximately 1 in 30-50 adults or about 4,000,000 Americans wit...

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News  69 results

New Adrenalectomy Guidelines Cover Surgery, Multispecialty Care
https://www.medscape.com/viewarticle/979619

Aug 23rd, 2022 - New adrenalectomy guidelines from the American Association of Endocrine Surgeons are aimed at assisting both specialist and general surgeons with perioperative adrenal care, including guidance on management of adrenal incidentalomas. Published onl...

Aldosterone Linked to Kidney Failure Risk, Irrespective of Diabetes
https://www.medpagetoday.com/nephrology/esrd/100117

Aug 8th, 2022 - Higher serum aldosterone levels were linked to a greater risk of kidney failure in chronic kidney disease (CKD), both for those with and without diabetes, a study showed. Every doubling in aldosterone level was associated with 11% (95% CI 1.04-1.1...

Test Can Predict Death Risk With Adrenal Tumors
https://www.medpagetoday.com/endocrinology/generalendocrinology/92767

May 24th, 2021 - An increased risk of death was seen with higher levels of autonomous cortisol secretion (ACS), a new study found. In a retrospective cohort of patients with adrenal incidentalomas, plasma cortisol level after a 1-mg dexamethasone suppression test ...

Alarmingly Low Rate of Primary Aldosteronism Detected, Treated
https://www.medpagetoday.com/endocrinology/steroids/91880

Mar 31st, 2021 - Primary aldosteronism (PA) has been underrecognized and probably undertreated in Canada, new research suggests. In a cohort study of 1.1 million adults with hypertension, a paltry 0.7% were screened for PA -- one of the most common causes of secon...

Few Adults at Risk for Primary Aldosteronism Get Screened
https://www.medscape.com/viewarticle/948177

Mar 29th, 2021 - NEW YORK (Reuters Health) - Only 3% of adults at high risk for primary aldosteronism (PA) are screened for the condition, according to a study presented at ENDO 2021, the Endocrine Society's annual meeting. "Primary aldosteronism causes persistent...

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Patient Education  3 results see all →