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About 683 results

ALLMedicine™ Diabetic Foot Infections Center

Research & Reviews  179 results

Clinical, microbiological and inflammatory markers of severe diabetic foot infections.
https://doi.org/10.1111/dme.14648
Diabetic Medicine : a Journal of the British Diabetic Ass... Aragón-Sánchez J, Víquez-Molina G et. al.

Jul 17th, 2021 - In addition to systemic inflammatory response syndrome (SIRS), various clinical signs, microbiological findings and inflammatory markers could be associated with severe diabetic foot infections (DFI). This study included a retrospective cohort of ...

Nanopore 16S Amplicon Sequencing Enhances the Understanding of Pathogens in Medically I...
https://doi.org/10.2337/db20-0907
Diabetes Moon J, Kim N et. al.

Jun 25th, 2021 - Diabetic foot infections (DFIs) cause substantial morbidity and mortality. The mainstay of the treatment is empiric antibiotics and surgical debridement in severe cases. In this study, we performed nanopore 16S rDNA sequencing from the debridement...

Long-term Mortality of a Cohort of Patients Undergoing Surgical Treatment for Diabetic ...
https://doi.org/10.1177/15347346211009425
The International Journal of Lower Extremity Wounds; Aragón-Sánchez J, Víquez-Molina G et. al.

Apr 29th, 2021 - We analyzed a retrospective cohort of 150 patients with diabetic foot infections (DFIs) who underwent surgical treatment to determine long-term outcomes. The median follow-up of the series was 7.6 years. Cox's proportional hazards model for surviv...

Comparative Evaluation of the Diagnostic Value of Procalcitonin and hsCRP for the Prese...
https://doi.org/10.1177/15347346211011849
The International Journal of Lower Extremity Wounds; Todorova AS, Dimova RB et. al.

Apr 29th, 2021 - The aim of this study is to compare the efficacy of procalcitonin (PCT) and high-sensitive C-reactive protein (hsCRP) as diagnostic biomarkers in patients with diabetes and mild-to-moderate diabetic foot infections. A total of 119 patients (102 wi...

A Comparative Analysis of Antibiotic Usage in Diabetic Foot Infections Against Healing ...
https://doi.org/10.1053/j.jfas.2020.05.024
The Journal of Foot and Ankle Surgery : Official Publicat... Kruszewska K, Wesolowska-Gorniak K et. al.

Apr 7th, 2021 - The study aimed to analyze bacterial flora in diabetic foot infection, empiric and targeted antibiotic therapy, and factors influencing wound healing duration. The study we undertook a review analysis of data in 118 cases of diabetic foot among 98...

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Guidelines  1 results

2012 Infectious Diseases Society of America clinical practice guideline for the diagnos...
https://doi.org/10.1093/cid/cis346
Clinical Infectious Diseases : an Official Publication Of... Lipsky BA, Berendt AR et. al.

May 24th, 2012 - Foot infections are a common and serious problem in persons with diabetes. Diabetic foot infections (DFIs) typically begin in a wound, most often a neuropathic ulceration. While all wounds are colonized with microorganisms, the presence of infecti...

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Drugs  56 results see all →

Clinicaltrials.gov  8 results

Ertapenem Sodium (MK-0826) Versus Piperacillin/Tazobactam Sodium for the Treatment of Diabetic Foot Infections in Chinese Adults (MK-0826-061)
https://clinicaltrials.gov/ct2/show/NCT01370616

Aug 27th, 2018 - This study compared ertapenem sodium to piperacillin/tazobactam sodium for the treatment of moderate to severe diabetic foot infections. The primary hypothesis was that treatment with ertapenem sodium is non-inferior to treatment with piperacillin...

A Trial to Assess Safety and Efficacy of Topical MBN-101 in Patients With Moderate/ Severe DFI
https://clinicaltrials.gov/ct2/show/NCT02723539

Aug 15th, 2018 - This is a randomized, double-blind, placebo-controlled, multi-center study that will be conducted in two parts. In Part I, patients will be enrolled into escalating dose cohorts (150, 375, or 600 µg/mL) (N=16/cohort) at a ratio of 3:1 (Active to P...

Risk Factors for Three Critical Stages of the Diabetic Foot Infections
https://clinicaltrials.gov/ct2/show/NCT02736253

Apr 13th, 2016 - In this study, it was aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation of the diabetic foot infection in the forward direction without using standard scoring procedures. Patients who were applied to...

Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections
https://clinicaltrials.gov/ct2/show/NCT00685698

Jan 9th, 2015 - This study will assess the safety and efficacy of TG-873870 (Nemonoxacin) in patients with Diabetic Foot Infections. Pharmacokinetic (PK) and pharmacodynamic (PD) assessment will be conducted in a subgroup of eight consenting patients.

Study Evaluating the Safety and Efficacy of Piperacillin/Tazobactam and Ampicillin/Sulbactam in Patients With Diabetic Foot Infections
https://clinicaltrials.gov/ct2/show/NCT00044746

Feb 8th, 2013 - Phase IV Open-Label Foot Infection Study is being conducted to generate comparative Efficacy and Safety data in Diabetic Inpatients.

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News  29 results

EMA Panel Backs Two Antibacterials, Cefiderocol and Generic Tigecycline
https://www.medscape.com/viewarticle/925981

Mar 2nd, 2020 - At its February meeting, the European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use (CHMP) recommended two antibacterial agents: cefiderocol and a generic version of tigecycline. Cefiderocol (Fetcroja, Shionogi BV) is f...

Many patients with diabetic foot infections get unnecessary MRSA treatment
https://www.mdedge.com/familymedicine/article/113703/infectious-diseases/many-patients-diabetic-foot-infections-get
Dermatology News; Lucas Franki

Sep 13th, 2016 - Many patients with diabetic foot infections receive methicillin-resistant Staphylococcus aureus antibiotics unnecessarily, according to Kelly Reveles, PharmD, and her associates. Among the 318 patients with diabetic foot infections (DFIs) in the s.

New Risk Score for Amputation in Infected Diabetic Foot Ulcers
https://www.medscape.com/viewarticle/840288

Feb 24th, 2015 - A new risk score for amputation in patients with infected diabetic foot ulcers that could be used easily in daily practice has been developed, with the researchers claiming it may have better prognostic accuracy than the current International Work...

A Diabetic Foot Infection Progresses to Amputation
https://www.mdedge.com/clinicianreviews/article/86359/diabetes/diabetic-foot-infection-progresses-amputation/page/0/1

Aug 11th, 2014 - Scientific principles Diabetic foot infections are associated with substantial morbidity and mortality. Important risk factors for development of diabetic foot infections include neuropathy, peripheral vascular disease, and poor glycemic control.

Diagnosis and treatment of diabetic foot infections
https://www.mdedge.com/familymedicine/article/58488/endocrinology/diagnosis-and-treatment-diabetic-foot-infections/page/0/1
Internal Medicine News;

Apr 22nd, 2013 - Some slow or nonresponding wounds may benefit from selected adjunctive measures such as bioengineered skin equivalents, growth factors, hyperbaric oxygen therapy, or negative-pressure wound therapy. Multidisciplinary diabetic foot care teams impro.

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