ALLMedicine™ Diabetic Foot Infections Center

Jul 17th, 2021 - In addition to systemic inflammatory response syndrome (SIRS), various clinical signs, microbiological findings and inflammatory markers could be associated with severe diabetic foot infections (DFI). This study included a retrospective cohort of ...

Jun 25th, 2021 - Diabetic foot infections (DFIs) cause substantial morbidity and mortality. The mainstay of the treatment is empiric antibiotics and surgical debridement in severe cases. In this study, we performed nanopore 16S rDNA sequencing from the debridement...

Apr 29th, 2021 - We analyzed a retrospective cohort of 150 patients with diabetic foot infections (DFIs) who underwent surgical treatment to determine long-term outcomes. The median follow-up of the series was 7.6 years. Cox's proportional hazards model for surviv...

Apr 29th, 2021 - The aim of this study is to compare the efficacy of procalcitonin (PCT) and high-sensitive C-reactive protein (hsCRP) as diagnostic biomarkers in patients with diabetes and mild-to-moderate diabetic foot infections. A total of 119 patients (102 wi...

Apr 7th, 2021 - The study aimed to analyze bacterial flora in diabetic foot infection, empiric and targeted antibiotic therapy, and factors influencing wound healing duration. The study we undertook a review analysis of data in 118 cases of diabetic foot among 98...

May 24th, 2012 - Foot infections are a common and serious problem in persons with diabetes. Diabetic foot infections (DFIs) typically begin in a wound, most often a neuropathic ulceration. While all wounds are colonized with microorganisms, the presence of infecti...

Aug 27th, 2018 - This study compared ertapenem sodium to piperacillin/tazobactam sodium for the treatment of moderate to severe diabetic foot infections. The primary hypothesis was that treatment with ertapenem sodium is non-inferior to treatment with piperacillin...

Aug 15th, 2018 - This is a randomized, double-blind, placebo-controlled, multi-center study that will be conducted in two parts. In Part I, patients will be enrolled into escalating dose cohorts (150, 375, or 600 µg/mL) (N=16/cohort) at a ratio of 3:1 (Active to P...

Apr 13th, 2016 - In this study, it was aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation of the diabetic foot infection in the forward direction without using standard scoring procedures. Patients who were applied to...

Jan 9th, 2015 - This study will assess the safety and efficacy of TG-873870 (Nemonoxacin) in patients with Diabetic Foot Infections. Pharmacokinetic (PK) and pharmacodynamic (PD) assessment will be conducted in a subgroup of eight consenting patients.

Feb 8th, 2013 - Phase IV Open-Label Foot Infection Study is being conducted to generate comparative Efficacy and Safety data in Diabetic Inpatients.

Mar 2nd, 2020 - At its February meeting, the European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use (CHMP) recommended two antibacterial agents: cefiderocol and a generic version of tigecycline. Cefiderocol (Fetcroja, Shionogi BV) is f...

Sep 13th, 2016 - Many patients with diabetic foot infections receive methicillin-resistant Staphylococcus aureus antibiotics unnecessarily, according to Kelly Reveles, PharmD, and her associates. Among the 318 patients with diabetic foot infections (DFIs) in the s.

Feb 24th, 2015 - A new risk score for amputation in patients with infected diabetic foot ulcers that could be used easily in daily practice has been developed, with the researchers claiming it may have better prognostic accuracy than the current International Work...

Aug 11th, 2014 - Scientific principles Diabetic foot infections are associated with substantial morbidity and mortality. Important risk factors for development of diabetic foot infections include neuropathy, peripheral vascular disease, and poor glycemic control.

Apr 22nd, 2013 - Some slow or nonresponding wounds may benefit from selected adjunctive measures such as bioengineered skin equivalents, growth factors, hyperbaric oxygen therapy, or negative-pressure wound therapy. Multidisciplinary diabetic foot care teams impro.