ALLMedicine™ Insulinoma Center

Nov 19th, 2020 - Aberrant expression of neuroendocrine markers has been reported in angiosarcomas and can occasionally result in diagnostic confusion. The aim of this study was to evaluate the expression of insulinoma-associated protein 1 (INSM1), a marker for neu...

Nov 9th, 2020 - Phenotypic screening is a neoclassical approach for drug discovery. We conducted phenotypic screening for insulin secretion enhancing agents using INS-1E insulinoma cells as a model system for pancreatic beta-cells. A principal regulator of insuli...

Oct 30th, 2020 - Pancreatic cystic insulinoma is an uncommon tumor. Perioperative localization remained challenging if the tumor is atypical with cystic feature or in small size. Near-infrared (NIR) imaging is a technique by injecting fluorescent dye intravenously...

Oct 22nd, 2020 - Di-(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP) are representative phthalic acid esters (PAEs), a class of environmental endocrine disruptors used as plasticizers. PAEs exposure is associated with glucose metabolism, insulin resista...

Oct 17th, 2020 - Insulinomas are pancreatic endocrine tumors characterized by hypoglycemia resulting from hypersecretion of insulin. The long-term impact of surgical treatment of insulinomas, particularly the risk of glucose metabolism disorders, remains largely u...

Nov 19th, 2020 - Aberrant expression of neuroendocrine markers has been reported in angiosarcomas and can occasionally result in diagnostic confusion. The aim of this study was to evaluate the expression of insulinoma-associated protein 1 (INSM1), a marker for neu...

Nov 9th, 2020 - Phenotypic screening is a neoclassical approach for drug discovery. We conducted phenotypic screening for insulin secretion enhancing agents using INS-1E insulinoma cells as a model system for pancreatic beta-cells. A principal regulator of insuli...

Oct 30th, 2020 - Pancreatic cystic insulinoma is an uncommon tumor. Perioperative localization remained challenging if the tumor is atypical with cystic feature or in small size. Near-infrared (NIR) imaging is a technique by injecting fluorescent dye intravenously...

Oct 22nd, 2020 - Di-(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP) are representative phthalic acid esters (PAEs), a class of environmental endocrine disruptors used as plasticizers. PAEs exposure is associated with glucose metabolism, insulin resista...

Oct 17th, 2020 - Insulinomas are pancreatic endocrine tumors characterized by hypoglycemia resulting from hypersecretion of insulin. The long-term impact of surgical treatment of insulinomas, particularly the risk of glucose metabolism disorders, remains largely u...

May 11th, 2019 - LOS ANGELES – The 69-year-old woman with a history of type 2 diabetes had persistent hypoglycemia despite treatment with hydrocortisone, dextrose, and glucagon. Doctors in South Carolina worried about insulinoma and planned to launch an intra-arte.

Feb 2nd, 2018 - The diagnosis: Metastatic insulinoma surrounded by steatotic hepatocytes The loss of L-FABP expression in steatotic hepatocytes is the hallmark of HNF1alpha-inactivated liver adenoma,1 and clearly suggested this diagnosis. However, the emergence o.

Dec 9th, 2010 - Dietary Intervention in Infancy and Later Signs of Beta-Cell Autoimmunity Knip M, Virtanen SM, Seppä K, et al; for the Finnish TRIGR (Trial to Reduce IDDM in the Genetically at Risk) Study Group N Engl J Med. 2010;363:1900-1908 Study Summary Knip ...

Aug 16th, 2004 - Diagnostic Questions If this patient has an insulinoma, are the history, physical, and laboratory findings "classic" or "unusual" in this particular presentation? View the correct answer. What imaging studies would you order? View the correct answ...

Nov 26th, 2001 - Discussion The CT scan (Fig 1) demonstrated a focal, hyperdense lesion of approximately 1 cm in diameter in the tail of the pancreas that is more readily seen using a narrow window width (Fig 2). The increased density indicates a hypervascular mas...