ALLMedicine™ Diabetic Ketoacidosis Center

Nov 28th, 2020 - The genesis of ketone bodies by organisms is a protective mechanism. This metabolic process helps organisms to survive acute metabolic derangements in times of nutrient deficiency. When prolonged, ketogenesis leads to ketoacidosis, which is a pote...

Nov 27th, 2020 - SGLT2-inhibitors (SGLT-2i) have been linked to the risk of potential life-threatening diabetic ketoacidosis (DKA). The U.S. Food and Drug Administration and the European Medicines Agency issued warnings in 2015 and 2016 respectively on the predisp...

Nov 20th, 2020 - The aim of the study was to evaluate the impact of an insulin infusion calculator incorporated into electronic health record system in reducing the rate of hypoglycemia in diabetic ketoacidosis (DKA) management. Retrospective chart review of patie...

Nov 17th, 2020 - Hamman's syndrome is a spontaneous pneumomediastinum and is described as a rare complication of diabetic ketoacidosis (DKA). It typically follows a self-limiting course after successful treatment of the underlying DKA. We describe a case of a 28-y...

Nov 16th, 2020 - Cerebral edema (CE) is a potentially devastating complication of diabetic ketoacidosis (DKA) that almost exclusively occurs in children. Since its first description in 19361 , numerous risk factors have been identified; however, there continues to...

Sep 16th, 2020 - The International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guideline 2018 for management of diabetic ketoacidosis (DKA) and the hyperglycemic hyperosmolar state provide comprehensive guidance for management of DKA ...

Aug 10th, 2020 - Diabetic ketoacidosis (DKA) is a serious medical emergency once considered typical of type 1 diabetes (T1DM), but now reported to occur in type 2 and GDM patients as well. DKA can cause severe complications and even prove fatal. The aim of our stu...

Jun 27th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

May 31st, 2019 - Sodium–glucose cotransporter (SGLT) inhibitors are new oral antidiabetes medications shown to effectively reduce glycated hemoglobin (A1C) and glycemic variability, blood pressure, and body weight without intrinsic properties to cause hypoglycemia...

Apr 10th, 2018 - The biochemical criteria for the diagnosis of diabetic ketoacidosis (DKA) are: Hyperglycemia (blood glucose >11 mmol/L [≈200 mg/dL]) Venous pH <7. 3 or serum bicarbonate <15 mmol/L Ketonemia (blood ß-hydroxybuyrate ≥3 mmol/L) or moderate or large k.

Nov 29th, 2020 - CYCLOSET is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. CYCLOSET is an ergot derivative indicated as an adjunct to diet and exercise to improve glycemic control in adults with t...

Nov 28th, 2020 - The genesis of ketone bodies by organisms is a protective mechanism. This metabolic process helps organisms to survive acute metabolic derangements in times of nutrient deficiency. When prolonged, ketogenesis leads to ketoacidosis, which is a pote...

Nov 27th, 2020 - SGLT2-inhibitors (SGLT-2i) have been linked to the risk of potential life-threatening diabetic ketoacidosis (DKA). The U.S. Food and Drug Administration and the European Medicines Agency issued warnings in 2015 and 2016 respectively on the predisp...

Nov 20th, 2020 - The aim of the study was to evaluate the impact of an insulin infusion calculator incorporated into electronic health record system in reducing the rate of hypoglycemia in diabetic ketoacidosis (DKA) management. Retrospective chart review of patie...

Nov 18th, 2020 - Repaglinide tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Limitation of Use: Repaglinide tablets should not be used in patients with type 1 diabetes mellitus or for th...

Oct 14th, 2020 - Children who had a single episode of moderate/severe diabetic ketoacidosis (DKA) and were newly diagnosed with type 1 diabetes had a subtle decline in a long-term memory task when they were tested a few months later in a new study. And other child...

Oct 14th, 2020 - Children who had a single episode of moderate/severe diabetic ketoacidosis (DKA) and were newly diagnosed with type 1 diabetes had a subtle decline in a long-term memory task when they were tested a few months later in a new study. And other child...

Oct 1st, 2020 - Recent studies have shown improved renal outcomes in adult patients with sepsis receiving balanced solutions instead of "normal" saline. For years, it has been known that 0.9% saline (colloquially referred to as "abnormal saline") can cause a hype...

Oct 1st, 2020 - Recent studies have shown improved renal outcomes in adult patients with sepsis receiving balanced solutions instead of "normal" saline. For years, it has been known that 0.9% saline (colloquially referred to as "abnormal saline") can cause a hype...

Jun 18th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. A new article in the Journal of Clinical Endocrinology & Metabolism (JCEM) addresses unique concerns and considerations regarding diabetic ketoaci...