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About 6,491 results

ALLMedicine Diabetic Neuropathy Center

Research & Reviews  2,989 results

Rapid glycemic regulation in poorly controlled patients living with diabetes, a new ass...
https://doi.org/10.1371/journal.pone.0233168
PloS One; Dardari D, Van GH et. al.

May 21st, 2020 - Aggressive antidiabetic therapy and rapid glycemic control are associated with diabetic neuropathy. Here we investigated if this is also the case for Charcot neuroarthropathy. HbA1c levels and other relevant data were extracted from medical databa...

Pharmacokinetics and Safety of Ranirestat in Patients With Hepatic Impairment.
https://doi.org/10.1002/jcph.1636
Journal of Clinical Pharmacology References; Itou M, Fujita T et. al.

May 21st, 2020 - Ranirestat is an aldose reductase inhibitor hypothesized to improve diabetic neuropathy. An open-label, single-dose, parallel-group study was conducted to compare pharmacokinetic (PK) characteristics of an oral dose of ranirestat across subjects w...

Inhibition of PI3K/AKT/mTOR signaling pathway promotes autophagy and relieves hyperalge...
https://doi.org/10.1097/WNR.0000000000001461
Neuroreport Liu K, Yang Y et. al.

May 19th, 2020 - The purpose of this study was to explore the role and mechanism of the PI3K/AKT/mTOR signaling pathway in painful diabetic neuropathy (PDN). The diabetes mellitus (DM) model was established by intraperitoneal injection of streptozocin into SD rats...

Selected pathobiological features and principles of pharmacological pain management.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232056
The Journal of International Medical Research; Khammissa RAG, Ballyram R et. al.

May 15th, 2020 - Pain induced by inflammation and nerve injury arises from abnormal neural activity of primary afferent nociceptors in response to tissue damage, which causes long-term elevation of the sensitivity and responsiveness of spinal cord neurons. Inflamm...

Effects of hydrotherapy with massage on serum nerve growth factor concentrations and ba...
https://doi.org/10.1016/j.ctcp.2020.101141
Complementary Therapies in Clinical Practice; Shourabi P, Bagheri R et. al.

May 7th, 2020 - and purpose: Nerve growth factor (NGF) concentrations and balance are reduced in diabetic neuropathy (DN) patients. We examined the effects of hydrotherapy and massage on NGF, balance and glycemic markers in middle aged DN patients. Patients were ...

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Guidelines  5 results

Diabetic neuropathy.
https://doi.org/10.1055/s-0034-1366435
Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association; Ziegler D, Keller J et. al.

Jul 11th, 2014 - Diabetic neuropathy.|2014|Ziegler D,Keller J,Maier C,Pannek J, ,|diagnosis,epidemiology,etiology,therapy,standards,standards,standards,methods,standards,

Methods of investigation for cardiac autonomic dysfunction in human research studies.
https://doi.org/10.1002/dmrr.1224
Diabetes/metabolism Research and Reviews; Bernardi L, Spallone V et. al.

Jun 22nd, 2011 - This consensus document provides evidence-based guidelines regarding the evaluation of diabetic cardiovascular autonomic neuropathy (CAN) for human research studies; the guidelines are the result of the work of the CAN Subcommittee of the Toronto ...

Cardiovascular autonomic neuropathy in diabetes: clinical impact, assessment, diagnosis...
https://doi.org/10.1002/dmrr.1239
Diabetes/metabolism Research and Reviews; Spallone V, Ziegler D et. al.

Jun 22nd, 2011 - The Cardiovascular Autonomic Neuropathy (CAN) Subcommittee of the Toronto Consensus Panel on Diabetic Neuropathy worked to update CAN guidelines, with regard to epidemiology, clinical impact, diagnosis, usefulness of CAN testing, and management. C...

Evidence-based guideline: Treatment of painful diabetic neuropathy: report of the Ameri...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100130
Neurology Bril V, England J et. al.

Apr 12th, 2011 - To develop a scientifically sound and clinically relevant evidence-based guideline for the treatment of painful diabetic neuropathy (PDN). We performed a systematic review of the literature from 1960 to August 2008 and classified the studies accor...

Evidence-based guideline: treatment of painful diabetic neuropathy--report of the Ameri...
https://doi.org/10.1002/mus.22092
Muscle & Nerve; Bril V, England JD et. al.

Apr 12th, 2011 - The objective of this report was to develop a scientifically sound and clinically relevant evidence-based guideline for the treatment of painful diabetic neuropathy (PDN). The basic question that was asked was: "What is the efficacy of a given tre...

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Drugs  2 results see all →

Clinicaltrials.gov  3,209 results

Rapid glycemic regulation in poorly controlled patients living with diabetes, a new ass...
https://doi.org/10.1371/journal.pone.0233168
PloS One; Dardari D, Van GH et. al.

May 21st, 2020 - Aggressive antidiabetic therapy and rapid glycemic control are associated with diabetic neuropathy. Here we investigated if this is also the case for Charcot neuroarthropathy. HbA1c levels and other relevant data were extracted from medical databa...

Pharmacokinetics and Safety of Ranirestat in Patients With Hepatic Impairment.
https://doi.org/10.1002/jcph.1636
Journal of Clinical Pharmacology References; Itou M, Fujita T et. al.

May 21st, 2020 - Ranirestat is an aldose reductase inhibitor hypothesized to improve diabetic neuropathy. An open-label, single-dose, parallel-group study was conducted to compare pharmacokinetic (PK) characteristics of an oral dose of ranirestat across subjects w...

Inhibition of PI3K/AKT/mTOR signaling pathway promotes autophagy and relieves hyperalge...
https://doi.org/10.1097/WNR.0000000000001461
Neuroreport Liu K, Yang Y et. al.

May 19th, 2020 - The purpose of this study was to explore the role and mechanism of the PI3K/AKT/mTOR signaling pathway in painful diabetic neuropathy (PDN). The diabetes mellitus (DM) model was established by intraperitoneal injection of streptozocin into SD rats...

Selected pathobiological features and principles of pharmacological pain management.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232056
The Journal of International Medical Research; Khammissa RAG, Ballyram R et. al.

May 15th, 2020 - Pain induced by inflammation and nerve injury arises from abnormal neural activity of primary afferent nociceptors in response to tissue damage, which causes long-term elevation of the sensitivity and responsiveness of spinal cord neurons. Inflamm...

Effects of hydrotherapy with massage on serum nerve growth factor concentrations and ba...
https://doi.org/10.1016/j.ctcp.2020.101141
Complementary Therapies in Clinical Practice; Shourabi P, Bagheri R et. al.

May 7th, 2020 - and purpose: Nerve growth factor (NGF) concentrations and balance are reduced in diabetic neuropathy (DN) patients. We examined the effects of hydrotherapy and massage on NGF, balance and glycemic markers in middle aged DN patients. Patients were ...

see more →

News  267 results

Standards for health claims in advertisements need to go up
https://www.mdedge.com/clinicalneurologynews/article/215388/business-medicine/standards-health-claims-advertisements-need?channel=41022
Allan M. Block, MD, Clinical Neurology News

Jan 10th, 2020 - Three months is how long I’ll leave a magazine out in my waiting room. When its lobby lifespan is up, I’ll usually recycle it, though sometimes will take it home to read myself when I have down time.

FDA Approves First Lyrica Generics
https://www.medscape.com/viewarticle/915877

Jul 21st, 2019 - The US Food and Drug Administration (FDA) has approved multiple applications for the first generics of pregabalin (Lyrica) for the management of neuropathic pain. The FDA granted approvals for the generic versions of Lyrica to Alembic Pharmaceutic...

Caution Urged on Use of Opioids for Diabetic Neuropathy 
https://www.medscape.com/viewarticle/914073

Jun 10th, 2019 - This transcript has been edited for clarity. Hi, my name is Andrew Boulton, professor of medicine at the University of Manchester, and visiting professor, University of Miami. This year, it's been a pleasure to be on the programme committee for th...

In T2D, Bariatric Surgery Is Tops for Microvascular Risk Reduction
https://www.medpagetoday.com/endocrinology/diabetes/74428

Aug 6th, 2018 - Action Points Researchers found significant reductions in incident microvascular disease in a retrospective review of electronic medical records of type 2 diabetes patients undergoing bariatric surgery compared with matched controls who had not ha...

Spinal-Cord Stimulation: Durable Pain Relief for Diabetic Neuropathy
https://www.medscape.com/viewarticle/889527

Dec 3rd, 2017 - Patients with painful diabetic peripheral neuropathy of the lower extremities can experience significant reductions in pain symptoms over the longer term with spinal-cord stimulation (SCS), new results from a 5-year prospective study indicate. The...

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Patient Education  19 results see all →