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About 797 results

ALLMedicine™ Hormone Action Center

Research & Reviews  397 results

Deiodinases and the Metabolic Code for Thyroid Hormone Action.
https://doi.org/10.1210/endocr/bqab059
Endocrinology Russo SC, Salas-Lucia F et. al.

Mar 15th, 2021 - Deiodinases modify the biological activity of thyroid hormone (TH) molecules, i.e. they may activate thyroxine (T4) to 3,5,3'-tri-iodothyronine (T3), or inactivate T3 to 3,3'-diiodo-L-thyronine (T2) or T4 to reverse tri-iodothyronine (rT3). Althou...

Thyroid hormone action in epidermal development and homeostasis and its implications in...
https://doi.org/10.1007/s40618-020-01492-2 10.1111/j.1365-2133.2005.06645.x 10.1016/j.molimm.2005.02.009 10.1111/j.0909-725X.2006.00135.x 10.1159/000112957 10.1146/annurev.cellbio.22.010305.104357 10.1126/science.1253734 10.1038/nature724 10.1111/j.1432-0436.2004.07208005.x 10.1083/jcb.129.5.1329 10.1111/1523-1747.ep12455517 10.1083/jcb.143.7.2009 10.1002/(SICI)1097-0177(200004)217:4<430::AID-DVDY10>3.0.CO;2-5 10.1016/j.pbb.2017.10.001 10.1210/er.2008-0019 10.1016/j.metabol.2008.02.003 10.1006/bbrc.1998.9974 10.1016/j.biocel.2011.05.016 10.1530/JOE-10-0448 10.1530/JOE-11-0002 10.1210/en.2017-00250 10.1172/JCI60047 10.1097/MED.0b013e328357b45e 10.1016/j.bbagen.2012.05.007 10.3390/v11111072 10.1111/1523-1747.ep12338692 10.1210/en.2009-0306 10.5694/mja2.50129 10.1016/j.anireprosci.2019.106236 10.1046/j.1523-1747.2002.19617.x 10.1074/jbc.M103144200 10.1002/bies.200800121 10.1210/endo-91-4-934 10.1210/endo-117-5-2106 10.1210/jc.2008-0283 10.1073/pnas.0706754104 10.1089/thy.2011.0105 10.1089/thy.2019.0557 10.1210/en.2003-1696 10.1016/j.bbrc.2017.06.066 10.1210/me.2004-0542 10.1007/s11626-013-9583-7 10.21037/tp.2017.09.08 10.1111/j.1529-8019.2010.01369.x 10.1046/j.1365-2362.2000.00590.x 10.1007/s12020-020-02188-6 10.1007/s12020-020-02505-z 10.1111/j.1365-2133.1964.tb14492.x 10.1016/j.mehy.2019.05.010 10.1038/jidsymp.2013.11 10.1038/jid.2009.359 10.1074/jbc.M111.218487 10.1371/journal.pone.0023825 10.1091/mbc.E14-07-1251 10.1089/thy.2017.0369 10.3389/fendo.2013.00104 10.1172/JCI84465 10.1038/s41467-019-13140-2 10.1016/j.cmet.2014.10.009 10.1016/j.psyneuen.2016.08.021 10.1210/en.2014-1698 10.3390/cancers12030715
Journal of Endocrinological Investigation; Mancino G, Miro C et. al.

Mar 8th, 2021 - Thyroid hormones (THs) are key endocrine regulators of tissue development and homeostasis. They are constantly released into the bloodstream and help to regulate many cell functions. The principal products released by the follicular epithelial cel...

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919419
Genes & Development; Shabtai Y, Nagaraj NK et. al.

Feb 19th, 2021 - Thyroid hormones (THs) are powerful regulators of metabolism with major effects on body weight, cholesterol, and liver fat that have been exploited pharmacologically for many years. Activation of gene expression by TH action is canonically ascribe...

The Deiodinases: Their Identification and Cloning of Their Genes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864002
Endocrinology Galton VA, Larsen PR et. al.

Jan 15th, 2021 - In this minireview, we provide a historical outline of the events that led to the identification and characterization of the deiodinases, the recognition that deiodination plays a major role in thyroid hormone action, and the cloning of the 3 deio...

The Gut Microbial Endocrine Organ in Type 2 Diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806240
Endocrinology Massey W, Brown JM

Dec 29th, 2020 - Historically, the focus of type II diabetes mellitus (T2DM) research has been on host metabolism and hormone action. However, emerging evidence suggests that the gut microbiome, commensal microbes that colonize the gastrointestinal tract, also pla...

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Clinicaltrials.gov  399 results

Deiodinases and the Metabolic Code for Thyroid Hormone Action.
https://doi.org/10.1210/endocr/bqab059
Endocrinology Russo SC, Salas-Lucia F et. al.

Mar 15th, 2021 - Deiodinases modify the biological activity of thyroid hormone (TH) molecules, i.e. they may activate thyroxine (T4) to 3,5,3'-tri-iodothyronine (T3), or inactivate T3 to 3,3'-diiodo-L-thyronine (T2) or T4 to reverse tri-iodothyronine (rT3). Althou...

Thyroid hormone action in epidermal development and homeostasis and its implications in...
https://doi.org/10.1007/s40618-020-01492-2 10.1111/j.1365-2133.2005.06645.x 10.1016/j.molimm.2005.02.009 10.1111/j.0909-725X.2006.00135.x 10.1159/000112957 10.1146/annurev.cellbio.22.010305.104357 10.1126/science.1253734 10.1038/nature724 10.1111/j.1432-0436.2004.07208005.x 10.1083/jcb.129.5.1329 10.1111/1523-1747.ep12455517 10.1083/jcb.143.7.2009 10.1002/(SICI)1097-0177(200004)217:4<430::AID-DVDY10>3.0.CO;2-5 10.1016/j.pbb.2017.10.001 10.1210/er.2008-0019 10.1016/j.metabol.2008.02.003 10.1006/bbrc.1998.9974 10.1016/j.biocel.2011.05.016 10.1530/JOE-10-0448 10.1530/JOE-11-0002 10.1210/en.2017-00250 10.1172/JCI60047 10.1097/MED.0b013e328357b45e 10.1016/j.bbagen.2012.05.007 10.3390/v11111072 10.1111/1523-1747.ep12338692 10.1210/en.2009-0306 10.5694/mja2.50129 10.1016/j.anireprosci.2019.106236 10.1046/j.1523-1747.2002.19617.x 10.1074/jbc.M103144200 10.1002/bies.200800121 10.1210/endo-91-4-934 10.1210/endo-117-5-2106 10.1210/jc.2008-0283 10.1073/pnas.0706754104 10.1089/thy.2011.0105 10.1089/thy.2019.0557 10.1210/en.2003-1696 10.1016/j.bbrc.2017.06.066 10.1210/me.2004-0542 10.1007/s11626-013-9583-7 10.21037/tp.2017.09.08 10.1111/j.1529-8019.2010.01369.x 10.1046/j.1365-2362.2000.00590.x 10.1007/s12020-020-02188-6 10.1007/s12020-020-02505-z 10.1111/j.1365-2133.1964.tb14492.x 10.1016/j.mehy.2019.05.010 10.1038/jidsymp.2013.11 10.1038/jid.2009.359 10.1074/jbc.M111.218487 10.1371/journal.pone.0023825 10.1091/mbc.E14-07-1251 10.1089/thy.2017.0369 10.3389/fendo.2013.00104 10.1172/JCI84465 10.1038/s41467-019-13140-2 10.1016/j.cmet.2014.10.009 10.1016/j.psyneuen.2016.08.021 10.1210/en.2014-1698 10.3390/cancers12030715
Journal of Endocrinological Investigation; Mancino G, Miro C et. al.

Mar 8th, 2021 - Thyroid hormones (THs) are key endocrine regulators of tissue development and homeostasis. They are constantly released into the bloodstream and help to regulate many cell functions. The principal products released by the follicular epithelial cel...

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919419
Genes & Development; Shabtai Y, Nagaraj NK et. al.

Feb 19th, 2021 - Thyroid hormones (THs) are powerful regulators of metabolism with major effects on body weight, cholesterol, and liver fat that have been exploited pharmacologically for many years. Activation of gene expression by TH action is canonically ascribe...

The Deiodinases: Their Identification and Cloning of Their Genes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864002
Endocrinology Galton VA, Larsen PR et. al.

Jan 15th, 2021 - In this minireview, we provide a historical outline of the events that led to the identification and characterization of the deiodinases, the recognition that deiodination plays a major role in thyroid hormone action, and the cloning of the 3 deio...

The Gut Microbial Endocrine Organ in Type 2 Diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806240
Endocrinology Massey W, Brown JM

Dec 29th, 2020 - Historically, the focus of type II diabetes mellitus (T2DM) research has been on host metabolism and hormone action. However, emerging evidence suggests that the gut microbiome, commensal microbes that colonize the gastrointestinal tract, also pla...

see more →

News  1 results

Using ACCORD to Target HbA1c: Think Ages and Stages
https://www.medscape.com/viewarticle/735118

Jan 3rd, 2011 - An Interview With Faramarz Ismail-Beigi, MD About the Interviewee Faramarz Ismail-Beigi, MD, PhD, is a Professor of Medicine, Endocrinology, and Physiology and Biophysics at Case Western Reserve University, University Hospitals of Cleveland, and t...

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