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About 793 results

ALLMedicine™ Hormone Action Center

Research & Reviews  395 results

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action...
https://doi.org/10.1101/gad.345686.120
Genes & Development; Shabtai Y, Nagaraj NK et. al.

Feb 19th, 2021 - Thyroid hormones (THs) are powerful regulators of metabolism with major effects on body weight, cholesterol, and liver fat that have been exploited pharmacologically for many years. Activation of gene expression by TH action is canonically ascribe...

The Deiodinases: Their Identification and Cloning of Their Genes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864002
Endocrinology Galton VA, Larsen PR et. al.

Jan 15th, 2021 - In this minireview, we provide a historical outline of the events that led to the identification and characterization of the deiodinases, the recognition that deiodination plays a major role in thyroid hormone action, and the cloning of the 3 deio...

The Gut Microbial Endocrine Organ in Type 2 Diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806240
Endocrinology Massey W, Brown JM

Dec 29th, 2020 - Historically, the focus of type II diabetes mellitus (T2DM) research has been on host metabolism and hormone action. However, emerging evidence suggests that the gut microbiome, commensal microbes that colonize the gastrointestinal tract, also pla...

Plasmid-borne colistin resistance gene mcr-1 in a multidrug resistant Salmonella enteri...
https://doi.org/10.1074/jbc.271.45.28235
International Journal of Infectious Diseases : IJID : Off... Li Y, Zhang Y et. al.

Nov 19th, 2020 - Thyroid hormone receptors bind DNA with highest affinity as heterodimers with retinoid X receptors, and such heterodimers generally are thought to be the biological mediators of thyroid hormone action. An alternative splice product of the thyroid ...

Cross-species physiological interactions of endocrine disrupting chemicals with the cir...
https://doi.org/10.1016/j.ygcen.2020.113650
General and Comparative Endocrinology; Bottalico LN, Weljie AM

Nov 9th, 2020 - Endocrine disrupting chemicals (EDCs) are endocrine-active chemical pollutants that disrupt reproductive, neuroendocrine, cardiovascular and metabolic health across species. The circadian clock is a transcriptional oscillator responsible for entra...

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Clinicaltrials.gov  397 results

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action...
https://doi.org/10.1101/gad.345686.120
Genes & Development; Shabtai Y, Nagaraj NK et. al.

Feb 19th, 2021 - Thyroid hormones (THs) are powerful regulators of metabolism with major effects on body weight, cholesterol, and liver fat that have been exploited pharmacologically for many years. Activation of gene expression by TH action is canonically ascribe...

The Deiodinases: Their Identification and Cloning of Their Genes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864002
Endocrinology Galton VA, Larsen PR et. al.

Jan 15th, 2021 - In this minireview, we provide a historical outline of the events that led to the identification and characterization of the deiodinases, the recognition that deiodination plays a major role in thyroid hormone action, and the cloning of the 3 deio...

The Gut Microbial Endocrine Organ in Type 2 Diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806240
Endocrinology Massey W, Brown JM

Dec 29th, 2020 - Historically, the focus of type II diabetes mellitus (T2DM) research has been on host metabolism and hormone action. However, emerging evidence suggests that the gut microbiome, commensal microbes that colonize the gastrointestinal tract, also pla...

Plasmid-borne colistin resistance gene mcr-1 in a multidrug resistant Salmonella enteri...
https://doi.org/10.1074/jbc.271.45.28235
International Journal of Infectious Diseases : IJID : Off... Li Y, Zhang Y et. al.

Nov 19th, 2020 - Thyroid hormone receptors bind DNA with highest affinity as heterodimers with retinoid X receptors, and such heterodimers generally are thought to be the biological mediators of thyroid hormone action. An alternative splice product of the thyroid ...

Cross-species physiological interactions of endocrine disrupting chemicals with the cir...
https://doi.org/10.1016/j.ygcen.2020.113650
General and Comparative Endocrinology; Bottalico LN, Weljie AM

Nov 9th, 2020 - Endocrine disrupting chemicals (EDCs) are endocrine-active chemical pollutants that disrupt reproductive, neuroendocrine, cardiovascular and metabolic health across species. The circadian clock is a transcriptional oscillator responsible for entra...

see more →

News  1 results

Using ACCORD to Target HbA1c: Think Ages and Stages
https://www.medscape.com/viewarticle/735118

Jan 3rd, 2011 - An Interview With Faramarz Ismail-Beigi, MD About the Interviewee Faramarz Ismail-Beigi, MD, PhD, is a Professor of Medicine, Endocrinology, and Physiology and Biophysics at Case Western Reserve University, University Hospitals of Cleveland, and t...

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