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About 224,773 results

ALLMedicine™ Insulin Center

Research & Reviews  71,510 results

Hybrid Closed Loop Overcomes the Impact of Missed or Suboptimal Meal Boluses on Glucose...
https://doi.org/10.1089/dia.2022.0518
Diabetes Technology & Therapeutics; Coutant R, Bismuth E et. al.

Mar 18th, 2023 - Background It is unclear whether hybrid closed-loop therapy (HCL) attenuates the metabolic impact of missed or suboptimal meal insulin bolus compared with sensor-augmented pump therapy (SAP) in children with type 1 diabetes in free-living conditio...

Donor noradrenaline use is associated with better allograft survival in recipients of p...
https://doi.org/10.1308/rcsann.2022.0161
Annals of the Royal College of Surgeons of England; Shapey IM, Summers A et. al.

Mar 18th, 2023 - Outcomes following pancreas transplantation are suboptimal and better donor selection is required to improve this. Vasoactive drugs (VaD) are commonly used to correct the abnormal haemodynamics of organ donors in intensive care units. VaDs can dif...

Impact of abdominal obesity on the risk of glioma development in patients with diabetes...
https://doi.org/10.1371/journal.pone.0283023
PloS One; Sang H, Cho YK et. al.

Mar 18th, 2023 - Abdominal obesity has been suggested as a risk factor for glioma; however, it is unclear whether this association applies to people with diabetes. This study examined the association between abdominal obesity and the risk of developing gliomas in ...

A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in...
https://doi.org/10.1038/s41556-023-01103-1
Nature Cell Biology; Rubio-Navarro A, Gómez-Banoy N et. al.

Mar 18th, 2023 - The pancreatic islets are composed of discrete hormone-producing cells that orchestrate systemic glucose homeostasis. Here we identify subsets of beta cells using a single-cell transcriptomic approach. One subset of beta cells marked by high CD63 ...

Intracutaneous Transplantation of Islets within a Biodegradable Temporizing Matrix (BTM...
https://doi.org/10.2337/db21-0841
Diabetes Rojas-Canales D, Walters SN et. al.

Mar 18th, 2023 - Intra-hepatic islet transplantation for type-1 diabetes is limited by the need for multiple infusions and poor islet viability post-transplantation. The development of alternative transplantation sites is necessary to improve islet survival, and f...

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Guidelines  46 results

Management of Individuals With Diabetes at High Risk for Hypoglycemia: An Endocrine Soc...
https://doi.org/10.1210/clinem/dgac596
The Journal of Clinical Endocrinology and Metabolism; McCall AL, Lieb DC et. al.

Dec 9th, 2022 - Hypoglycemia in people with diabetes is common, especially in those taking medications such as insulin and sulfonylureas (SU) that place them at higher risk. Hypoglycemia is associated with distress in those with diabetes and their families, medic...

Guideline No. 430: Diagnosis and management of preterm prelabour rupture of membranes.
https://doi.org/10.1016/j.jogc.2022.08.014
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Ronzoni S, Boucoiran I et. al.

Nov 22nd, 2022 - To provide clear and concise guidelines for the diagnosis and management of preterm prelabour rupture of membranes (PPROM) TARGET POPULATION: All patients with PPROM <37 weeks gestation BENEFITS, HARMS, AND COSTS: This guideline aims to provide th...

American Association of Clinical Endocrinology Clinical Practice Guideline: Developing ...
https://doi.org/10.1016/j.eprac.2022.08.002
Endocrine Practice : Official Journal of the American Col... Blonde L, Umpierrez GE et. al.

Aug 14th, 2022 - The objective of this clinical practice guideline is to provide updated and new evidence-based recommendations for the comprehensive care of persons with diabetes mellitus to clinicians, diabetes-care teams, other health care professionals and sta...

Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268041/
Molecules Chavda VP, Ajabiya J et. al.

Jul 5th, 2022 - The prevalence of obesity and diabetes is an increasing global problem, especially in developed countries, and is referred to as the twin epidemics. As such, advanced treatment approaches are needed. Tirzepatide, known as a ‘twincretin’, is a ‘fir...

Could the development of COVID-19 vaccine-induced type 1 diabetes be explained by a simple mechanism?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904174/
Diabetes & Metabolism; Sasaki H, Itoh A et. al.

Jul 3rd, 2022 - To the Editor We read with great interest the article “Fulminant type 1 diabetes (T1DM) after Covid-19 vaccination” by Tang et al. in this journal [1]. The authors examined islet autoantibodies, HLA alleles, and the capacity for insulin secreti...

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Drugs  490 results see all →

Clinicaltrials.gov  11,002 results

Effects of Sucralose in Insulin Sensitivity, Intestinal Microbiota and Postprandial GLP-1
https://clinicaltrials.gov/ct2/show/NCT04182464

Mar 14th, 2023 - Study design: This is a triple-blind, parallel, placebo-controlled, randomized clinical trial. Sample size: The sample size was calculated to observe a difference of 15% in insulin sensitivity based on two outcomes: glucose rate of appearance (Ra)...

Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis
https://clinicaltrials.gov/ct2/show/NCT02988401

Mar 10th, 2023 - Cognitive impairment is common in and devastating to people with MS. MS is a common, chronic, central nervous system (CNS) disease characterized by inflammation, demyelination, and neurodegeneration. One of the most devastating symptoms of this di...

The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction
https://clinicaltrials.gov/ct2/show/NCT03679780

Mar 10th, 2023 - Cardiovascular disease (CVD) afflicts nearly one-third of the adult population with all races and ethnicities represented in CVD prevalence. Unfortunately, a disparity exists such that the black population (BL) is disproportionately affected compa...

The Effects of Metformin on Morbidity and Mortality in Elderly Patients
https://clinicaltrials.gov/ct2/show/NCT04530058

Mar 10th, 2023 - Elderly patients have an increased susceptibility to burns and a substantial mortality that has not significantly changed over the last three decades. Elderly burn patients not only have an augmented response to burn but also express a prolonged h...

Pharmacogenomics of GLP1 Receptor Agonists
https://clinicaltrials.gov/ct2/show/NCT05762744

Mar 10th, 2023 - Healthy volunteers were recruited from the Old Order Amish population in Lancaster County, Pennsylvania. After providing informed consent, research participants were screened for eligibility. The clinical trial was designed as a randomized crossov...

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News  6,708 results

Long COVID Easing? Wyoming Bans Abortion Pills; Hep A Outbreak Tied to Strawberries
https://www.medpagetoday.com/infectiousdisease/longcovid/103604

Mar 20th, 2023 - Note that some links may require subscriptions. A Washington Post analysis suggests long COVID symptoms have become less common since the Omicron variant. Military pilots have higher rates of cancer, as do aircraft ground crews, a Pentagon study f...

Evidence COVID Began in Raccoon Dog; Migraine Drug Recall; FDA Mum on Spring Booster
https://www.medpagetoday.com/infectiousdisease/covid19/103579

Mar 17th, 2023 - Note that some links may require subscriptions. A new analysis of genetic samples from China appears to link the origin of COVID-19 to raccoon dogs. (The Atlantic) What's a raccoon dog, anyhow? (Wikipedia) After a 2-year pandemic spike, maternal d...

Another Artificial Pancreas a Success in Tots With Type 1 Diabetes
https://www.medpagetoday.com/endocrinology/type1diabetes/103548

Mar 15th, 2023 - Very young children with type 1 diabetes saw glycemic benefits when using a hybrid closed-loop system, the randomized PEDAP trial showed. Among 102 children ages 2 to 5 years, the mean percentage of time that the glucose level was within the targe...

Child, Teen Deaths Surge; EPA Moves to Limit PFAS in Water; Return of Black Lung
https://www.medpagetoday.com/pediatrics/generalpediatrics/103536

Mar 15th, 2023 - Note that some links may require subscriptions. The mortality rate of children and teens rose sharply in 2020 and 2021, driven by factors unrelated to COVID-19 itself. (JAMA) Drugmaker Novo Nordisk said it will slash its insulin prices, following ...

PFAS Limit in Water? Novo Nordisk to Cut Insulin Prices; Cosmetic Endo Trending
https://www.medpagetoday.com/endocrinology/generalendocrinology/103523

Mar 14th, 2023 - The Biden administration proposed the first-ever limit on PFAS in drinking water. If finalized, the nationwide limit on the endocrine-disrupting chemicals PFOA and PFOS would be capped at 4 parts per trillion. (The Hill) Over the past 20 years, pr...

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Patient Education  153 results see all →