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About 132,543 results

ALLMedicine™ Insulin Center

Research & Reviews  48,694 results

Postloading insulinemia is independently associated with arterial stiffness in young Ja...
https://doi.org/10.1038/s41440-021-00749-4 10.2174/138161209789105072 10.2174/1381612811319320005 10.1016/j.medcli.2016.12.029 10.1291/hypres.30.237 10.3389/fcvm.2019.00041 10.5551/jat.E515 10.1111/j.1464-5491.2010.03144.x 10.1155/2013/151675 10.1007/s00125-015-3602-z 10.2337/dc16-1773 10.1161/01.str.29.8.1498 10.1161/01.cir.0000015855.04844.e7 10.1016/s0167-5273(02)00018-9 10.1007/s00125-005-1711-9 10.2337/diacare.28.4.860 10.1016/j.atherosclerosis.2017.09.031 10.1111/dme.12026 10.1371/journal.pone.0044470 10.1177/1479164117736509 10.1111/cen.13280 10.2337/dc17-1351 10.1530/EJE-17-0824 10.2147/DMSO.S246062 10.1161/01.cir.92.6.1422 10.2337/diab.45.6.736 10.1016/j.numecd.2015.06.009 10.1038/sj.jhh.1001526 10.1093/eurheartj/ehq165 10.1016/j.acvd.2010.03.004 10.1186/1475-2840-10-30 10.3803/EnM.2015.30.3.326 10.1186/s13098-017-0247-8 10.1111/j.2040-1124.2010.00074.x 10.1111/cen.14073 10.1515/CCLM.2003.189 10.2337/diacare.22.9.1462 10.2337/dc10-0646 10.1007/BF00280883 10.1093/clinchem/18.6.499 10.1177/1099800415574902 10.1007/s00125-020-05245-x 10.1210/er.2018-00141 10.1002/hep.26988 10.1002/hep4.1155 10.1161/HYPERTENSIONAHA.118.11554
Hypertension Research : Official Journal of the Japanese ... Murai N, Saito N et. al.

Sep 15th, 2021 - Associations of arterial stiffness with glucose, insulin, and proinsulin dynamics during the oral glucose tolerance test (OGTT) remain under debate. The aim of this study was to investigate whether plasma glucose (PG), insulin, and proinsulin (Pro...

GLP-1 receptor agonist treatment of high-carbohydrate intake-induced metabolic syndrome...
https://doi.org/10.1111/1440-1681.13590
Clinical and Experimental Pharmacology & Physiology; Durak A, Akkus E et. al.

Sep 15th, 2021 - The pleiotropic effects of glucagon-like peptide-1 receptor (GLP-1R) agonists on the heart have been recognized in obese or diabetic patients. However, little is known regarding the molecular mechanisms of these agonists in cardioprotective action...

Changes in adiposity mediate the associations of diet quality with insulin sensitivity ...
https://doi.org/10.1016/j.numecd.2021.07.025
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Lai KZH, Semnani-Azad Z et. al.

Sep 15th, 2021 - To examine the mediating role of adiposity on the associations of diet quality with longitudinal changes in insulin sensitivity and beta-cell function. Adults at-risk for type 2 diabetes (T2D) in the PROMISE cohort had 4 assessments over 9 years (...

Effects of GLP-1 receptor agonists on myokine levels and pro-inflammatory cytokines in ...
https://doi.org/10.1016/j.numecd.2021.07.015
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Guarnotta V, Bianco MJ et. al.

Sep 15th, 2021 - To evaluate the change in circulating serum irisin and interleukin-6 (IL-6), in patients with type 2 diabetes mellitus (T2DM) after 6 and 12 months of GLP-1 treatment. Eighty-five patients with T2DM inadequately controlled with insulin or other hy...

miR-221, miR-190b, miR-363-3p, miR-200c are involved in rat liver ischemia-reperfusion ...
https://doi.org/10.1111/ijcp.14848
International Journal of Clinical Practice; Tanoglu EG, Tanoglu A et. al.

Sep 15th, 2021 - In this study, it was aimed to investigate the relationship between expression levels of micrornas, endoplasmic reticulum (ER) stress, apoptosis and oxidative stress markers in hepatic ischemia reperfusion (IR) injury. Sixteen rats were randomized...

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Guidelines  34 results

Glucose management for exercise using continuous glucose monitoring (CGM) and intermitt...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702152
Pediatric Diabetes; Moser O, Riddell MC et. al.

Oct 14th, 2020 - Physical exercise is an important component in the management of type 1 diabetes across the lifespan. Yet, acute exercise increases the risk of dysglycaemia, and the direction of glycaemic excursions depends, to some extent, on the intensity and d...

ISPAD Clinical Practice Consensus Guideline: Diabetic ketoacidosis in the time of COVID...
https://doi.org/10.1111/pedi.13118
Pediatric Diabetes; Priyambada L, Wolfsdorf JI et. al.

Sep 17th, 2020 - The International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guideline 2018 for management of diabetic ketoacidosis (DKA) and the hyperglycemic hyperosmolar state provide comprehensive guidance for management of DKA ...

Pharmacologic Approaches to Glycemic Treatment of Type 2 Diabetes: Synopsis of the 2020...
https://doi.org/10.7326/M20-2470
Annals of Internal Medicine; Doyle-Delgado K, Chamberlain JJ et. al.

Sep 1st, 2020 - The American Diabetes Association (ADA) updates the Standards of Medical Care in Diabetes annually to provide clinicians, patients, researchers, payers, and other interested parties with evidence-based recommendations for the diagnosis and managem...

Multinational Association of Supportive Care in Cancer (MASCC) 2020 clinical practice r...
https://doi.org/10.1007/s00520-020-05709-1
Supportive Care in Cancer : Official Journal of the Multi... Cooksley T, Girotra M et. al.

Aug 29th, 2020 - Immune checkpoint inhibitors (ICIs) have emerged as the newest pillar of cancer treatment, transforming outcomes in melanoma and showing benefit in a range of malignancies. Immune-mediated toxicities, stemming from increased activity within the T ...

Nutraceuticals and blood pressure control: a European Society of Hypertension position ...
https://doi.org/10.1097/HJH.0000000000002353 10.1016/j.clnu.2019.08.015
Journal of Hypertension; Borghi C, Tsioufis K et. al.

Jan 25th, 2020 - : High-normal blood pressure (BP) is associated with an increased risk of cardiovascular disease, however the cost-benefit ratio of the use of antihypertensive treatment in these patients is not yet clear. Some dietary components and natural produ...

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Drugs  310 results see all →

Clinicaltrials.gov  143 results

Sirtuin-NAD+ Activator in Alzheimer's Disease
https://clinicaltrials.gov/ct2/show/NCT05040321

Sep 10th, 2021 - The sirtuin family of nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase enzymes are important regulators of the aging process (1-5) and mediate many of the beneficial effects of caloric restriction (6-9). The upregulation of the sirtu...

A Study to Learn How Well a Blood Sugar Monitoring System Called Cascade Which Measures Glucose on an Ongoing Basis Works and How Safe it is in Chinese Patients in Usual Practice
https://clinicaltrials.gov/ct2/show/NCT05038761

Sep 9th, 2021 - Researchers are looking for a better way to help Chinese people who have diabetes to monitor their blood sugar situation. There are 2 types of diabetes. In people with type 1 diabetes, the body's immune system attacks and destroys cells in the pan...

Empagliflozin for the Treatment of Postprandial Hypoglycemia
https://clinicaltrials.gov/ct2/show/NCT05036317

Sep 5th, 2021 - Postprandial hypoglycemia is a debilitating medical complication after bariatric surgery for which no approved pharmacological treatment exists. The prevalence of hypoglycemia in bariatric patients ranges from 0.5 % severe episodes up to 56 % and ...

Effect of Nutrition Supplementation Combined With Resistance Exercise in Elderly With Sarcopenia.
https://clinicaltrials.gov/ct2/show/NCT05035121

Sep 5th, 2021 - The anthropometry data included body weight and body fat. The sarcopenia index included appendicular skeletal muscle mass index, calf circumferences, hand grip and gait speed. Moreover, blood biochemical index (liver function as ALT, kidney functi...

Alpelisib, Fulvestrant and Dapagliflozin for the Treatment of HR+, HER2 -, PIK3CA Mutant Metastatic Breast Cancer
https://clinicaltrials.gov/ct2/show/NCT05025735

Sep 2nd, 2021 - Alpelisib is a p110α specific PI3K inhibitor that has shown significant clinical benefit in patients with HR+/HER2 negative mBC harboring activating PIK3CA mutations. The SOLAR-1 study randomized patients with MBC progressing after aromatase inhib...

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News  3,830 results

New FDA Guidance on T2D Trial Design Provides Flexibility
https://www.medscape.com/viewarticle/954346

Jul 20th, 2021 - This transcript has been edited for clarity. The story of cardiovascular outcomes in diabetes is a fascinating one. There were new developments in the regulatory landscape that really drove the past 10 years of history. If you go way back to the f...

Cancer Drug May Slow Course of Type 1 Diabetes
https://www.medscape.com/viewarticle/954931

Jul 19th, 2021 - NEW YORK (Reuters Health) - The tyrosine-kinase inhibitor imatinib used to treat chronic myeloid leukemia and other cancers may help preserve beta-cell function in people with recently diagnosed type-1 diabetes, according to findings from a phase-...

With Tirzepatide, a 'Great Future' for Patients With T2D
https://www.medscape.com/viewarticle/954345

Jul 15th, 2021 - This transcript has been edited for clarity. I'm here to talk about tirzepatide, a dual GIP/GLP-1 receptor agonists that's under investigation for the management of type 2 diabetes, obesity, and fatty liver disease. We're all very used to GLP-1 re...

Fecal Transplantation, Boosted by Fiber, Improves Insulin in Obesity
https://www.medscape.com/viewarticle/954783

Jul 14th, 2021 - As use of fecal microbial transplantation evolves, new research shows that a noninvasive approach ― with an oral capsule formulation ― combined with fiber supplementation significantly improved insulin sensitivity among those with severe obesity a...

Abiraterone/Prednisone Combo Linked With Improvements in Fatigue and QoL, But Worsening Metabolic Changes in mCRPC
https://www.onclive.com/view/abiraterone-prednisone-combo-linked-with-improvements-in-fatigue-and-qol-but-worsening-metabolic-changes

Jul 12th, 2021 - Abiraterone acetate (Zytiga) plus prednisone should be considered as the first treatment choice for patients with newly diagnosed metastatic castration-resistant prostate cancer (mCRPC) if fatigue is a concern. However, the regimen has been associ...

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Patient Education  6 results see all →