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About 16,214 results

ALLMedicine™ Acidosis Center

Research & Reviews  7,849 results

Lessons of the month: Pyroglutamic acidosis: long-term paracetamol and a high anion gap.
https://doi.org/10.7861/clinmed.2020-0363
Clinical Medicine (London, England); Trevor-Jones E, Hughes LT et. al.

Sep 16th, 2020 - An 84-year-old woman presented in extremis with confusion and Kussmaul respiration. She had a history of urosepsis, renal impairment and osteoarthrosis. The venous blood gas showed a marked metabolic acidosis with a high anion gap. Lactate and ket...

The mitochondrial DNA variant m.9032T>C in MT-ATP6 encoding p.(Leu169Pro) causes a comp...
https://doi.org/10.1016/j.mito.2020.08.009
Mitochondrion Knight KM, Shelkowitz E et. al.

Sep 15th, 2020 - Diagnosing complex V deficiencies caused by new variants in mitochondrial DNA is challenging due to the rarity, phenotypic diversity, and limited functional assessments. We describe a child with the m.9032T>C variant in MT-ATP6 encoding p.(Leu169P...

The effect of diabetic ketoacidosis (DKA) and its treatment on clot microstructure: Are...
https://doi.org/10.3233/CH-200957
Clinical Hemorheology and Microcirculation; Pillai S, Davies G et. al.

Sep 14th, 2020 - Diabetic ketoacidosis (DKA) is a medical emergency with a high mortality rate and is associated with severe metabolic acidosis and dehydration. DKA patients have an increased risk of arterial and venous thromboembolism, however little is known abo...

Veverimer: An Emerging Potential Treatment Option for Managing the Metabolic Acidosis o...
https://doi.org/10.1053/j.ajkd.2020.07.019
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation; Adrogué HJ, Madias NE

Sep 13th, 2020 - Sodium bicarbonate is the mainstay treatment of the metabolic acidosis of CKD but associated concerns center on administering sodium to patients with hypertension and sodium-retentive states. Veverimer (formerly TRC101) is a novel, non-absorbable ...

The phenotype associated with variants in TANGO2 may be explained by a dual role of the...
https://doi.org/10.1002/jimd.12312
Journal of Inherited Metabolic Disease; Milev MP, Saint-Dic D et. al.

Sep 10th, 2020 - TANGO2 variants result in a complex disease phenotype consisting of recurrent crisis-induced rhabdomyolysis, encephalopathy, seizures, lactic acidosis, hypoglycemia, and cardiac arrhythmias. Although first described in a fruit fly model as a prote...

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Guidelines  5 results

Vibrio Cholerae - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK526099/

Nov 17th, 2018 - Cholera is a well-known disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. This potentially fatal diarrheal disease results in large volumes of watery stool, causing rapid dehydration that can progress to hyp...

Diagnosis and Treatment of Metabolic Acidosis in Patients with Chronic Kidney Disease -...
https://doi.org/10.1159/000490475
Kidney & Blood Pressure Research; Adamczak M, Masajtis-Zagajewska A et. al.

Jun 12th, 2018 - Metabolic acidosis is commonly found in patients with chronic kidney disease (CKD), and its causes are: impaired ammonia excretion, reduced tubular bicarbonate reabsorption and insufficient renal bicarbonate production in relation to the amount of...

Practical Approach to Detection and Management of Chronic Kidney Disease for the Primary Care Clinician
https://www.amjmed.com/article/S0002-9343(15)00855-4/pdf
The American Journal of Medicine; Vassalotti,J.,et al

Feb 1st, 2016 - A panel of internists and nephrologists developed this practical approach for the Kidney Disease Outcomes Quality Initiative to guide assessment and care of chronic kidney disease (CKD) by primary care clinicians. Chronic kidney disease is defined...

ACR Appropriateness Criteria® growth disturbances - risk of intrauterine growth restric...
https://doi.org/10.1097/RUQ.0b013e31829ea221
Ultrasound Quarterly; Zelop CM, Javitt MC et. al.

Jul 22nd, 2013 - Fetal growth disturbances include fetuses at risk for intrauterine growth restriction. These fetuses may have an estimated fetal weight at less than the 10% or demonstrate a plateau of fetal growth with an estimated fetal growth greater than the 1...

Prevention and treatment of protein energy wasting in chronic kidney disease patients: ...
https://doi.org/10.1038/ki.2013.147
Kidney International; Ikizler TA, Cano NJ et. al.

May 23rd, 2013 - Protein energy wasting (PEW) is common in patients with chronic kidney disease (CKD) and is associated with adverse clinical outcomes, especially in individuals receiving maintenance dialysis therapy. A multitude of factors can affect the nutritio...

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Drugs  187 results see all →

Clinicaltrials.gov  8,069 results

Lessons of the month: Pyroglutamic acidosis: long-term paracetamol and a high anion gap.
https://doi.org/10.7861/clinmed.2020-0363
Clinical Medicine (London, England); Trevor-Jones E, Hughes LT et. al.

Sep 16th, 2020 - An 84-year-old woman presented in extremis with confusion and Kussmaul respiration. She had a history of urosepsis, renal impairment and osteoarthrosis. The venous blood gas showed a marked metabolic acidosis with a high anion gap. Lactate and ket...

The mitochondrial DNA variant m.9032T>C in MT-ATP6 encoding p.(Leu169Pro) causes a comp...
https://doi.org/10.1016/j.mito.2020.08.009
Mitochondrion Knight KM, Shelkowitz E et. al.

Sep 15th, 2020 - Diagnosing complex V deficiencies caused by new variants in mitochondrial DNA is challenging due to the rarity, phenotypic diversity, and limited functional assessments. We describe a child with the m.9032T>C variant in MT-ATP6 encoding p.(Leu169P...

The effect of diabetic ketoacidosis (DKA) and its treatment on clot microstructure: Are...
https://doi.org/10.3233/CH-200957
Clinical Hemorheology and Microcirculation; Pillai S, Davies G et. al.

Sep 14th, 2020 - Diabetic ketoacidosis (DKA) is a medical emergency with a high mortality rate and is associated with severe metabolic acidosis and dehydration. DKA patients have an increased risk of arterial and venous thromboembolism, however little is known abo...

Veverimer: An Emerging Potential Treatment Option for Managing the Metabolic Acidosis o...
https://doi.org/10.1053/j.ajkd.2020.07.019
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation; Adrogué HJ, Madias NE

Sep 13th, 2020 - Sodium bicarbonate is the mainstay treatment of the metabolic acidosis of CKD but associated concerns center on administering sodium to patients with hypertension and sodium-retentive states. Veverimer (formerly TRC101) is a novel, non-absorbable ...

The phenotype associated with variants in TANGO2 may be explained by a dual role of the...
https://doi.org/10.1002/jimd.12312
Journal of Inherited Metabolic Disease; Milev MP, Saint-Dic D et. al.

Sep 10th, 2020 - TANGO2 variants result in a complex disease phenotype consisting of recurrent crisis-induced rhabdomyolysis, encephalopathy, seizures, lactic acidosis, hypoglycemia, and cardiac arrhythmias. Although first described in a fruit fly model as a prote...

see more →

News  103 results

Phase III Success for CKD Complication Tx
https://www.medpagetoday.com/nephrology/generalnephrology/80747

Jun 27th, 2019 - The investigational drug veverimer was safe and effective for treating patients with metabolic acidosis from chronic kidney disease, according to phase III data. In a 40-week extension study, only 2% of those on veverimer had serious adverse event...

A couple of little known side effects of medications
https://www.mdedge.com/rheumatology/article/195681/nephrology/couple-little-known-side-effects-medications?channel=216
Douglas S. Paauw, MD

Mar 5th, 2019 - A 46-year-old woman with diabetes and seizure disorder presents with nausea and fatigue. Her physical exam is unremarkable.

Cannabis May Help UC Patients: Gastro Endo News Report
https://www.medpagetoday.com/gastroenterology/generalgastroenterology/76868

Dec 12th, 2018 - Patients with moderate ulcerative colitis may benefit from cannabis, according to a new study that reported a decrease in disease activity index in patients who used the drug. A recent analysis found that consuming probiotics may contribute to sma...

Vibrio Cholerae - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK526099/

Nov 17th, 2018 - Cholera is a well-known disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. This potentially fatal diarrheal disease results in large volumes of watery stool, causing rapid dehydration that can progress to hyp...

Epinephrine Questioned; Sticky LDL; HTN in Pregnancy
https://www.medpagetoday.com/cardiology/prevention/73888

Jul 5th, 2018 - Epinephrine and norepinephrine are not interchangeable for the treatment of cardiogenic shock in myocardial infarction (MI), according to the results of a 57-person trial. Epinephrine was associated with "very transient" improvement in cardiac ind...

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Patient Education  1 results see all →