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ALLMedicine™ Acidosis Center

Research & Reviews  3,662 results

Infective Endocarditis with Pseudoaneurysm of the Mitral-Aortic Intervalvular Fibrosa P...
https://www.ncbi.nlm.nih.gov/pubmed/34323872
Rhode Island Medical Journal (2013); Soares C, Arikan P et. al.

Jul 30th, 2021 - A 79-year-old male with a history of ESRD and treated MRSA endocarditis was found to have a recurrence of MRSA bacteremia. He was treated with antibiotics. During his hospitalization, he suddenly developed complete heart block requiring transcutan...

Hyperkalemia in Chronic Kidney Disease in the New Era of Kidney Protection Therapies.
https://doi.org/10.1007/s40265-021-01555-5 10.1001/archinte.160.16.2429 10.1016/j.jacc.2020.04.021 10.1016/j.ijcard.2017.07.035 10.1038/ki.1977.73 10.1152/advan.00121.2016 10.1152/ajpendo.00539.2015 10.1038/sj.ki.5002288 10.1016/j.semnephrol.2019.04.005 10.1038/ki.2015.243 10.1016/j.resuscitation.2015.07.017 10.1136/bmj.286.6372.1189 10.1001/archinte.158.8.917 10.1001/archinternmed.2009.132 10.7861/clinmedicine.15-3-239 10.1111/ijcp.13421 10.1186/s12882-018-1007-1 10.1016/j.nefro.2018.11.011 10.1161/HYPERTENSIONAHA.116.07363 10.1016/j.ekir.2020.11.021 10.1159/000508980 10.1016/S0140-6736(18)31694-5 10.1093/ndt/gfz174 10.1093/ckj/sfz129 10.2215/CJN.05850809 10.2215/CJN.01150112 10.1080/0886022X.2016.1216714 10.1186/s12882-019-1250-0 10.1159/000442393 10.1111/dme.13687 10.1093/eurheartj/suy028 10.1002/ejhf.1079 10.1093/ndt/gfx053 10.2215/CJN.04451206 10.1053/j.ajkd.2016.09.015 10.1007/s40620-014-0115-7 10.2215/CJN.00960112 10.1097/01.ASN.0000026611.07106.A7 10.2215/CJN.03880411 10.1053/j.ajkd.2010.03.022 10.1038/ki.2010.315 10.1159/000360094 10.1053/j.ajkd.2016.04.011 10.1016/S0002-9343(01)01068-3 10.1053/j.ajkd.2008.04.031 10.1038/sj.ki.5001657 10.1093/ndt/gft515 10.1111/j.1525-139X.2007.00367.x 10.1016/S0272-6386(96)90465-5 10.1159/000448341 10.1159/000502998 10.1093/ndt/gfp104 10.1053/j.ajkd.2016.10.024 10.1159/000437151 10.2215/CJN.01730215 10.1093/ndt/gfx312 10.1186/s12882-017-0710-7 10.1186/cc11872 10.1093/ndt/gfy249 10.1016/0002-8703(67)90174-3 10.1681/ASN.2016121344 10.1093/eurheartj/ehy100 10.1161/CIRCULATIONAHA.117.030576 10.1161/JAHA.120.017087 10.1097/00000441-197105000-00007 10.1097/00005792-198605000-00004 10.1681/ASN.V641134 10.1136/jcp.25.6.512 10.1016/j.nefro.2019.04.011 10.1172/JCI115544 10.1053/j.ajkd.2019.03.427 10.1186/s13613-019-0509-8 10.1056/NEJMra1503102 10.1007/s11154-016-9384-x 10.1016/0022-2828(95)90070-5 10.1053/j.ajkd.2017.09.003 10.1056/NEJMoa0801317 10.2215/CJN.07460713 10.1056/NEJM199604113341502 10.1016/S0140-6736(98)10363-X 10.1056/NEJMoa011161 10.1056/NEJMoa011303 10.1007/s00125-010-1922-6 10.1056/NEJMoa1208799 10.1056/NEJMoa1303154 10.1007/s40256-018-00321-5 10.1097/MAJ.0000000000000475 10.1016/j.amjmed.2020.03.037 10.2174/1381612825666190306162658 10.2174/1573402115666190415155512 10.1097/HJH.0000000000001940 10.1097/HJH.0000000000002187 10.1517/14740330903499257 10.1056/NEJM199909023411001 10.1056/NEJMoa040135 10.1053/j.ajkd.2007.10.040 10.1159/000237742 10.1002/cmdc.201200081 10.1007/164_2016_76 10.1001/jama.2015.10081 10.1016/j.jdiacomp.2016.11.021 10.1159/000503713 10.1056/NEJMoa2025845 10.1161/HYPERTENSIONAHA.117.10360 10.1681/ASN.2012111094 10.1159/000503712 10.2215/CJN.08960718 10.2215/CJN.02430312 10.1053/j.jrn.2016.02.005 10.2215/CJN.02830409 10.1001/archinte.158.1.26 10.1038/ki.2015.249 10.1093/ckj/sfaa198 10.1093/ckj/sfz070 10.1002/ejhf.2026 10.1056/NEJMoa1811744 10.1038/kisup.2012.73 10.1152/ajprenal.00343.2020 10.1053/j.ajkd.2019.07.016 10.1007/s40620-019-00656-5 10.1053/j.ajkd.2020.07.019 10.1124/jpet.120.000190 10.1016/S0140-6736(19)31388-1 10.1016/S0140-6736(18)32562-5 10.2215/CJN.07300717 10.1093/eurheartj/suy032 10.1161/HYPERTENSIONAHA.115.04889 10.1016/j.phrs.2016.07.032 10.1001/jama.2014.15688 10.1056/NEJMoa1410853 10.1001/jama.2015.7446 10.1159/000504078 10.2215/CJN.12651018 10.1093/ndt/gfz285 10.1093/eurheartj/ehq502 10.1016/S0140-6736(19)32135-X 10.1126/science.abf3363 10.1371/journal.pone.0186665 10.1001/jama.288.19.2421 10.1210/en.2004-0233 10.1056/NEJMoa1402686
Drugs Valdivielso JM, Balafa O et. al.

Jul 28th, 2021 - Despite recent therapeutic advances, chronic kidney disease (CKD) is one of the fastest growing global causes of death. This illustrates limitations of current therapeutic approaches and, potentially, unidentified knowledge gaps. For decades, reni...

Bartter syndrome and hypothyroidism masquerading cystinosis in a 3-year-old girl: rare ...
https://doi.org/10.1136/bcr-2021-242954
BMJ Case Reports; Das G, Nanda PM et. al.

Jul 28th, 2021 - Cystinosis is a multisystem disorder with varied presentations secondary to deposition of cystine crystals in different organ systems. Children with cystinosis typically present with renal tubular acidosis and failure to thrive. We report a 3-year...

Estrogen protects against acidosis-mediated articular chondrocyte injury by promoting A...
https://doi.org/10.1016/j.ejphar.2021.174381
European Journal of Pharmacology; Su JW, Li SF et. al.

Jul 27th, 2021 - Epidemiological data suggest that the incidence of rheumatoid arthritis (RA) increases in postmenopausal women, which may be related to estrogen deficiency. Tissue acidosis is a common symptom of RA. Acid-sensitive ion channel 1a (ASIC1a), a membe...

Changes in S100B and troponin levels in a fetal sheep model of worsening acidosis.
https://doi.org/10.1016/j.ejogrb.2021.06.042
European Journal of Obstetrics, Gynecology, and Reproduct... Hamoud Y, Pekar JD et. al.

Jul 26th, 2021 - S100B and cardiac troponin T (c-TnT) are relevant biomarkers at birth of hypoxic-ischemic encephalopathy (HIE) and myocardial ischemia secondary to metabolic acidosis during labor, respectively. The purpose was to assess in-utero changes in S100B ...

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Guidelines  2 results

Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critical...
https://doi.org/10.1097/CCM.0000000000002027
Critical Care Medicine; Murray MJ, DeBlock H et. al.

Oct 19th, 2016 - To update the 2002 version of "Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient." A Task Force comprising 17 members of the Society of Critical Medicine with particular expertise in the use of n...

Evaluation and management of small-bowel obstruction: an Eastern Association for the Su...
https://doi.org/10.1097/TA.0b013e31827019de
The Journal of Trauma and Acute Care Surgery; Maung AA, Johnson DC et. al.

Dec 27th, 2012 - Small-bowel obstruction (SBO) represents as many as 16% of surgical admissions and more than 300,000 operations annually in the United States. The optimal strategies for the diagnosis and management of SBO continue to evolve secondary to advances ...

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Drugs  161 results see all →

Clinicaltrials.gov  136 results

Small-Volume, Patient-Specific, Balanced Hypertonic Fluid Protocol Validation
https://clinicaltrials.gov/ct2/show/NCT03330704

Mar 19th, 2020 - Many patients with traumatic brain injuries (including strokes, blood clots, or other brain injuries) are given concentrated salt water solutions (hypertonic saline) in order to treat brain swelling (cerebral edema). Current therapies consist of a...

Non Invasive Haemodynamics in Neuraxial Anaesthesia Hypotension
https://clinicaltrials.gov/ct2/show/NCT03653442

Mar 4th, 2020 - Hypotension induced by neuraxial anaesthesia (NA-induced hypotension) is defined as systolic blood pressure (SBP) less than 100 mmHg or a decrease of 20-30% from baseline values. The incidence of hypotension could exceed 71% and can cause, if seri...

Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis
https://clinicaltrials.gov/ct2/show/NCT03710291

Mar 3rd, 2020 - This is a randomized, double-blind, placebo-controlled trial. Eligible subjects will be randomized in a 1:1 ratio to TRC101 or placebo. The primary endpoint of the study will be progression of renal disease, defined by time to first occurrence of ...

Early Aggressive Correction of Severe Acidosis With Tris-hydroxymethylaminomethane (THAM)
https://clinicaltrials.gov/ct2/show/NCT01326260

Feb 17th, 2020 - The study objective is to assess the efficacy of fluid resuscitation and treatment of acidosis in patients who were managed with use of amine buffer THAM (tris-hydroxymethlaminomethane) versus those who were resuscitated with crystalloids or collo...

The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients
https://clinicaltrials.gov/ct2/show/NCT03277677

Feb 6th, 2020 - The high chloride content of 0.9%sodium chloride (0.9%NaCl) leads to adverse pathophysiological effects in both animals and healthy human volunteers. Small randomized trials confirm that the hyperchloremic acidosis induced by 0.9%NaCl also occurs ...

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News  218 results

Hospira, Inc. Issues a Voluntary Nationwide Recall of 8.4% Sodium Bicarbonate Injection, USP Due to the Presence of Particulate Matter | FDA
https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/hospira-inc-issues-voluntary-nationwide-recall-84-sodium-bicarbonate-injection-usp-due-presence

Summary Company Announcement Date: March 15, 2019 FDA Publish Date: March 15, 2019 Product Type: Drugs Generic Drugs Reason for Announcement: Recall Reason Description Presence of Particulate Matter Company Name: Hospira, Inc. Brand Name: Brand Na...

Optimal Sedation Strategies for COVID-19 ICU Patients
https://www.medscape.com/viewarticle/938901

Oct 9th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. According to the best available evidence, analagosedation remains the focus for managing COVID-19 ICU patients, according to Steven B. Greenberg, ...

Solutions for Diabetic Ketoacidosis: Finding the Right Balance
https://www.medscape.com/viewarticle/938029

Oct 2nd, 2020 - Recent studies have shown improved renal outcomes in adult patients with sepsis receiving balanced solutions instead of "normal" saline. For years, it has been known that 0.9% saline (colloquially referred to as "abnormal saline") can cause a hype...

Solutions for Diabetic Ketoacidosis: Finding the Right Balance
https://www.staging.medscape.com/viewarticle/938029

Oct 2nd, 2020 - Recent studies have shown improved renal outcomes in adult patients with sepsis receiving balanced solutions instead of "normal" saline. For years, it has been known that 0.9% saline (colloquially referred to as "abnormal saline") can cause a hype...

BMD, Modifiable Risk Factors Linked to Poor Outcomes in Chronic Kidney Disease
https://www.medscape.com/viewarticle/934272

Jul 22nd, 2020 - NEW YORK (Reuters Health) - In patients with chronic kidney disease (CKD) who are not on dialysis, modifiable lifestyle factors, including low physical activity and a high dietary sodium/potassium ratio, are associated with and may predict poor re...

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Patient Education  1 results see all →