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About 7,691 results

ALLMedicine™ Hypercalcemia Center

Research & Reviews  3,077 results

Gain-of-function mutations in acid stress response (evgS) protect Escherichia coli from...
https://doi.org/10.1128/AAC.01595-20
Antimicrobial Agents and Chemotherapy; Zeng J, Wu L et. al.

Dec 1st, 2020 - Widespread antimicrobial resistance encourages repurposing/refining of non-antimicrobial drugs for antimicrobial indications. Gallium nitrate (GaNt), an FDA-approved medication for cancer-related hypercalcemia, recently showed good activity agains...

Do the heterozygous carriers of a CYP24A1 mutation display a different biochemical phen...
https://doi.org/10.1210/clinem/dgaa876
The Journal of Clinical Endocrinology and Metabolism; Brancatella A, Cappellani D et. al.

Nov 29th, 2020 - Human cytochrome P450 24 subfamily A member 1 (CYP24A1) loss-of-function mutations result in impaired activity of the 24-hydroxylase involved in vitamin D catabolism, thus inducing a vitamin D-dependent hypercalcemia. Homozygotes often present an ...

Calcium channels blockers toxins attenuate abdominal hyperalgesia and inflammatory resp...
https://doi.org/10.1016/j.ejphar.2020.173672
European Journal of Pharmacology; Ricardo Carvalho VP, Figueira da Silva J et. al.

Nov 16th, 2020 - Agents that modulate the activity of high-voltage gated calcium channels (HVCCs) exhibit experimentally and clinically significant effect by relieving visceral pain. Among these agents, the toxins Phα1β and ω-conotoxin MVIIA effectively reduce chr...

Presymptomatic diagnosis of CYP24A1-related infantile idiopathic hypercalcemia: A case ...
https://doi.org/10.1016/j.ejmg.2020.104100
European Journal of Medical Genetics; Mirea AM, Pop RM et. al.

Nov 13th, 2020 - Vitamin D plays an important role in calcium homeostasis and bone mineralization. Inefficient inactivation of vitamin D leads to a condition called idiopathic infantile hypercalcemia (IIH). In the last decade mutations in CYP24A1, the gene respons...

Parathyroid Carcinoma: A Single-Institution Experience with an Emphasis on Histopatholo...
https://doi.org/10.1007/s12105-020-01244-x
Head and Neck Pathology; Sali AP, Motghare P et. al.

Nov 5th, 2020 - Parathyroid carcinoma (PC) is a rare malignancy that poses a diagnostic challenge on histologic examination. We analyzed various clinicopathologic features of PC. Pathology reports and slides were reviewed to evaluate the diagnostic histopathologi...

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Guidelines  2 results

Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494249
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology; Cook LB, Fuji S et. al.

Jan 18th, 2019 - Adult T-cell leukemia-lymphoma (ATL) is a distinct mature T-cell malignancy caused by chronic infection with human T-lymphotropic virus type 1 with diverse clinical features and prognosis. ATL remains a challenging disease as a result of its diver...

Multiple Myeloma, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology.
https://doi.org/10.6004/jnccn.2017.0023
Journal of the National Comprehensive Cancer Network : JNCCN; Kumar SK, Callander NS et. al.

Feb 11th, 2017 - Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone marrow causing skeletal damage, a hallmark of multiple myeloma. Other MM-r...

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Drugs  603 results see all →

Clinicaltrials.gov  3,809 results

Gain-of-function mutations in acid stress response (evgS) protect Escherichia coli from...
https://doi.org/10.1128/AAC.01595-20
Antimicrobial Agents and Chemotherapy; Zeng J, Wu L et. al.

Dec 1st, 2020 - Widespread antimicrobial resistance encourages repurposing/refining of non-antimicrobial drugs for antimicrobial indications. Gallium nitrate (GaNt), an FDA-approved medication for cancer-related hypercalcemia, recently showed good activity agains...

Do the heterozygous carriers of a CYP24A1 mutation display a different biochemical phen...
https://doi.org/10.1210/clinem/dgaa876
The Journal of Clinical Endocrinology and Metabolism; Brancatella A, Cappellani D et. al.

Nov 29th, 2020 - Human cytochrome P450 24 subfamily A member 1 (CYP24A1) loss-of-function mutations result in impaired activity of the 24-hydroxylase involved in vitamin D catabolism, thus inducing a vitamin D-dependent hypercalcemia. Homozygotes often present an ...

Prednisone - prednisone tablet-NCS HealthCare of KY, Inc dba Vangard Labs
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0102376b-8b25-43fc-9657-bee3d3041f6d

Nov 23rd, 2020 - Prednisone tablets and solutions are indicated in the following conditions: Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice: synthetic analogs may be used in conjunction with mineralocorticoids wh...

Prednisone - prednisone tablet-McKesson Corporation dba SKY Packaging
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=480e2573-7ad2-48a0-9c97-bcc5587aa7fe

Nov 22nd, 2020 - Prednisone tablets, USP are indicated in the following conditions: Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineraloco...

Prednisone - prednisone tablet-NuCare Pharmaceuticals,Inc.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4c983bd-24a5-714d-e053-2a95a90a240c

Nov 22nd, 2020 - Prednisone tablets are indicated in the following conditions: 1. Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineralocort...

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News  191 results

A 42-Year-Old Man With Backache and Fatigue After a Divorce
https://reference.medscape.com/viewarticle/933451_4

Jul 8th, 2020 - Other differential diagnoses were considered in this patient. Nonsteroidal anti-inflammatory drugs and analgesic drugs can cause acute kidney injury or acute interstitial nephritis, especially with long-term use or in individuals with preexisting ...

Fast Five Quiz: Squamous Cell Non-Small Cell Lung Cancer
https://reference.medscape.com/viewarticle/928233_3

May 26th, 2020 - A cavitary lesion in a proximal bronchus is considered the classic manifestation of squamous cell lung carcinoma. Histologically, it is characterized by the presence of keratin pearls and can be detected with cytologic studies because it has a ten...

Right hip and pelvic pain
https://www.mdedge.com/familymedicine/article/216309/endocrinology/right-hip-and-pelvic-pain/page/0/4?channel=114
MDedge Family Medicine;

Jan 28th, 2020 - Bisphosphonates are a Tx mainstay Indications for treatment include symptomatic or asymptomatic disease with any of the following: elevated sAP with pagetic changes at sites where complications could occur; sAP more than 2 to 4 times the upper lim.

High-dose Vitamin D Supplementation Appears to Be Safe
https://www.staging.medscape.com/viewarticle/923030

Dec 23rd, 2019 - NEW YORK (Reuters Health) - Vitamin D supplementation in doses up to 10,000 IU/day appears to be safe and well tolerated, though higher doses increase the risk of hypercalciuria and mild hypercalcemia, according to a secondary analysis from the Ca...

Severe hypercalcemia in a 54-year-old woman
https://www.mdedge.com/ccjm/article/211105/emergency-medicine/severe-hypercalcemia-54-year-old-woman/page/0/2?channel=263

Nov 1st, 2019 - Imaging reports A nuclear bone scan showed increased bone uptake in the hip and both shoulders, consistent with arthritis, and increased activity in 2 of the lower left ribs, associated with rib fractures secondary to lytic lesions. A skeletal sur.

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Patient Education  9 results see all →