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ALLMedicine™ Hypernatremia Center

Research & Reviews  329 results

The usefulness of copeptin for the diagnosis of nephrogenic diabetes insipidus in infan...
Journal of Pediatric Endocrinology & Metabolism : JPEM; Bitencourt L, Fischer BL et. al.

Jul 23rd, 2021 - We report a case of an infant with nephrogenic diabetes insipidus (NDI) diagnosed by the measurement of serum copeptin. There is only one study that previously evaluated the use of copeptin measurement in a pediatric patient. We present a 10-month...

The lack of free water on ICU: Mere fluid-balances are not enough with regard to hypern...
Journal of Critical Care; Rugg C, Schmid S et. al.

Jul 16th, 2021 - The lack of free water on ICU: Mere fluid-balances are not enough with regard to hypernatremia.|2021|Rugg C,Schmid S,Kreutziger J,Ströhle M,|

Animal models for diabetes insipidus.
Handbook of Clinical Neurology; Mahía J, Bernal A

Jul 10th, 2021 - The hormone arginine vasopressin (AVP) is a nonapeptide synthesized by hypothalamic magnocellular nuclei and secreted from the posterior pituitary into the bloodstream. It binds to AVP receptor 2 in the kidney to promote the insertion of aquaporin...

A cross-sectional survey of hospitalization and blood tests implementation status in pa...
Expert Opinion on Drug Safety; Imai S, Momo K et. al.

Jul 7th, 2021 - Hypernatremia and liver injury are typical adverse effects of tolvaptan. Therefore, hospitalization and frequent monitoring of serum sodium concentration and liver function are necessary for tolvaptan initiation. We performed a cross-sectional sur...

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Drugs  9 results see all →

Clinicaltrials.gov  13 results

Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill Patients

Apr 30th, 2019 - HYDRA is a randomized clinical trial designed to evaluate safety and efficiency of hydrochlorothiazide in critical patients with hypernatremia

Hypertonic Saline 75% vs Mannitol 20%

Nov 6th, 2018 - Raised intracranial pressure occurs following an expansion of an intracranial mass e.g. hematoma or brain tumor and if left untreated, can lead to brain ischemia, stroke and death. Strategies for reducing raised intracranial pressure include hyper...

Tolvaptan for Patients With Acute Neurological Injuries

Sep 24th, 2018 - Hyponatremia occurs frequently in patients with acute brain injury in the days to weeks following the acute injury, and may contribute to adverse outcome (1). In addition, hyponatremia can aggravate neurologic dysfunction, complicate neurological ...

Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)

Aug 17th, 2018 - Any adult patient with a pituitary adenoma (either non-functioning, prolactin-secreting, growth hormone secreting, gonadotropin secreting, or TSH (thyroid stimulating hormone) secreting) or cyst scheduled to undergo transsphenoidal resection will ...

Diet as a Potential Treatment for Autosomal Dominant Polycystic Kidney Disease

Mar 30th, 2017 - Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease with an estimated 600,000 persons affected in the United States and 12.5 million persons worldwide. To date, no disease-modifying treatment has been ...

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News  16 results

Inpatient Sodium Imbalances Linked to Adverse COVID-19 Outcomes

Mar 10th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Both high and low serum sodium levels are associated with adverse outcomes for hospitalized patients with COVID-19, new research suggests. In the ...

Fast Five Quiz: Heart Failure Presentation and Diagnosis

Apr 23rd, 2020 - BNP is the strongest predictor of heart failure vs other causes of dyspnea. High LV filling pressures stimulate the release of BNP, which exerts diuretic, natriuretic, and antihypertensive effects by inhibiting the renin-angiotensin-aldosterone sy...

Cardiorenal syndrome
Benjamin J. Freda, DO

May 1st, 2018 - To the Editor: I read with interest the thoughtful review of cardiorenal syndrome by Drs. Thind, Loehrke, and Wilt 1 and the accompanying editorial by Dr.

Pediatric Heat-Related Illnesses

Jun 3rd, 2016 - Further diagnostic evaluation is directed at determining the degree of multisystem organ dysfunction that results from heatstroke. A head computed tomography (CT) scan can evaluate for cerebral edema, whereas a comprehensive metabolic profile (CMP.

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