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About 91,503 results

ALLMedicine™ Insulin Resistance Center

Research & Reviews  44,835 results

Linagliptin, a DPP-4 inhibitor, ameliorates Aβ (1-42) peptides induced neurodegeneratio...
https://doi.org/10.1016/j.neuropharm.2021.108662
Neuropharmacology Siddiqui N, Ali J et. al.

Jun 13th, 2021 - Alzheimer's disease (AD) is the most devastating neurodegenerative disorder, accounting over 46 million cases of dementia globally. Evidence supports that Brain Insulin Resistance (BIR) due to serine phosphorylation of Insulin Receptor Substrate-1...

Increased regulated on activation, normal T-cell expressed and secreted levels and cyst...
https://doi.org/10.1016/j.fertnstert.2021.05.093
Fertility and Sterility; Juan CC, Chen KH et. al.

Jun 13th, 2021 - To study the relationship between circulating chemokine cysteine-cysteine motif ligand (CCL) 5 levels and cysteine-cysteine chemokine receptor type 5 (CCR5) expression in peripheral blood mononuclear cells (PBMCs) and adipose tissue with hyperandr...

Gut Bacteria Induce Granzyme B Expression in Human Colonic ILC3s In Vitro in an IL-15-D...
https://doi.org/10.4049/jimmunol.2000239
Journal of Immunology (Baltimore, Md. : 1950); Castleman MJ, Dillon SM et. al.

Jun 12th, 2021 - Heart failure (HF) affects up to over 20% of patients with type 2 diabetes (T2DM), even more in the elderly. Although, in T2DM, both hyperglycemia and the proinflammatory status induced by insulin resistance are crucial in cardiac function impairm...

Independent association of plasma xanthine oxidoreductase activity with hypertension in...
https://doi.org/10.1038/s41440-021-00679-1 10.1056/NEJMra0800885 10.1038/s41440-020-0532-z 10.1159/000381106 10.1371/journal.pone.0100801 10.1161/01.HYP.36.6.1072 10.5551/jat.31591 10.1136/bmj.j2376 10.1152/ajpendo.00378.2020 10.1007/s00775-014-1210-x 10.1016/j.bbadis.2014.05.022 10.1016/j.pharep.2015.05.004 10.1016/j.jchromb.2016.10.033 10.1016/j.metabol.2017.01.031 10.1253/circj.CJ-18-0082 10.1111/jdi.12982 10.1507/endocrj.EJ19-0053 10.1507/endocrj.EJ18-0127 10.1111/jdi.13207 10.1038/s41598-020-61463-8 10.1016/j.ijcard.2016.11.077 10.1053/j.ajkd.2008.12.034 10.1007/BF00280883 10.1016/S0021-9258(18)77283-9 10.1016/0009-2797(92)90093-Z 10.1074/jbc.274.8.4985 10.1371/journal.pone.0143560 10.1097/HJH.0000000000001204 10.4070/kcj.2019.0379 10.1016/j.mce.2012.04.013 10.1016/j.cjca.2020.02.066 10.1016/j.pathophys.2008.04.003 10.1038/nrendo.2017.56 10.1038/s41584-018-0004-x 10.1161/HYPERTENSIONAHA.120.16547 10.1097/HJH.0000000000001077 10.3390/ijms131115475 10.1016/S0022-5347(17)42404-9 10.1093/ajh/hpaa044 10.1111/jch.14153 10.1016/j.ejphar.2016.03.055 10.18502/rmm.v6i1.3919 10.1111/jch.13707 10.1016/j.atherosclerosis.2018.10.007
Hypertension Research : Official Journal of the Japanese ... Furuhashi M, Higashiura Y et. al.

Jun 12th, 2021 - Xanthine oxidoreductase (XOR), a rate-limiting and catalyzing enzyme of uric acid formation in purine metabolism, is involved in reactive oxygen species generation. Plasma XOR activity has been shown to be a novel metabolic biomarker related to ob...

Subsequent attempt tyrosine kinase inhibitor discontinuation in patients with chronic m...
https://doi.org/10.3390/ijms22115810
Hematological Oncology; Ureshino H, Kamachi K et. al.

Jun 12th, 2021 - Changes in lifestyle in developed countries have triggered the prevalence of obesity and type 2 diabetes mellitus (T2DM) in the latest years. Consequently, these metabolic diseases associated to insulin resistance, and the morbidity associated wit...

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Guidelines  33 results

Fasting Triglycerides & Glucose Index: A Useful Screening Test for Assessing Insulin Resistance in Patients Diagnosed with Rheumatoid Arthritis & Systemic Lupus Erythematosus
https://dmsjournal.biomedcentral.com/articles/10.1186/s13098-019-0495-x
Diabetology & Metabolic Syndrome; Contreras-Haro B,et al

Nov 26th, 2019 - Insulin resistance (IR) is frequently observed in patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). In clinical practice, IR assessment is limited to a low proportion of patients due to cost and equipment and technical...

Comparison of salivary nitric oxide and oral health in diabetic patients with and without xerostomia
https://www.sciencedirect.com/science/article/pii/S1871402119305752?via%3Dihub
Diabetes & Metabolic Syndrome; Abadi PA,et al

Nov 24th, 2019 - Diabetes mellitus (DM) is a chronic multi-systemic metabolic disorder; diabetic patients are more prone to xerostomia and oral health problems than others. There are evidences that nitric oxide (NO) plays an important role in healthy salivary glan...

DYSGLYCEMIA-BASED CHRONIC DISEASE: AN AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS POSI...
http://journals.aace.com/doi/10.4158/PS-2018-0139
Mechanick, J.,et al

Oct 31st, 2018 - The American Association of Clinical Endocrinologists (AACE) has created a dysglycemia-based chronic disease (DBCD) multimorbidity care model consisting of four distinct stages along the insulin resistance-prediabetes-type 2 diabetes (T2D) spectru.

Perioperative Pathways: Enhanced Recovery After Surgery
https://www.acog.org/Clinical-Guidance-and-Publications/Committee-Opinions/Committee-on-Gynecologic-Practice/Perioperative-Pathways-Enhanced-Recovery-After-Surgery
Committee on Gynecologic Practice

Aug 31st, 2018 - Gynecologic surgery is very common: hysterectomy alone is one of the most frequently performed operating room procedures each year. It is well known that surgical stress induces a catabolic state that leads to increased cardiac demand, relative ti.

ACOG Committee Opinion No. 750 Summary: Perioperative Pathways: Enhanced Recovery After...
https://doi.org/10.1097/AOG.0000000000002819
Obstetrics and Gynecology;

Aug 22nd, 2018 - Gynecologic surgery is very common: hysterectomy alone is one of the most frequently performed operating room procedures each year. It is well known that surgical stress induces a catabolic state that leads to increased cardiac demand, relative ti...

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Clinicaltrials.gov  45,531 results

Linagliptin, a DPP-4 inhibitor, ameliorates Aβ (1-42) peptides induced neurodegeneratio...
https://doi.org/10.1016/j.neuropharm.2021.108662
Neuropharmacology Siddiqui N, Ali J et. al.

Jun 13th, 2021 - Alzheimer's disease (AD) is the most devastating neurodegenerative disorder, accounting over 46 million cases of dementia globally. Evidence supports that Brain Insulin Resistance (BIR) due to serine phosphorylation of Insulin Receptor Substrate-1...

Increased regulated on activation, normal T-cell expressed and secreted levels and cyst...
https://doi.org/10.1016/j.fertnstert.2021.05.093
Fertility and Sterility; Juan CC, Chen KH et. al.

Jun 13th, 2021 - To study the relationship between circulating chemokine cysteine-cysteine motif ligand (CCL) 5 levels and cysteine-cysteine chemokine receptor type 5 (CCR5) expression in peripheral blood mononuclear cells (PBMCs) and adipose tissue with hyperandr...

Gut Bacteria Induce Granzyme B Expression in Human Colonic ILC3s In Vitro in an IL-15-D...
https://doi.org/10.4049/jimmunol.2000239
Journal of Immunology (Baltimore, Md. : 1950); Castleman MJ, Dillon SM et. al.

Jun 12th, 2021 - Heart failure (HF) affects up to over 20% of patients with type 2 diabetes (T2DM), even more in the elderly. Although, in T2DM, both hyperglycemia and the proinflammatory status induced by insulin resistance are crucial in cardiac function impairm...

Independent association of plasma xanthine oxidoreductase activity with hypertension in...
https://doi.org/10.1038/s41440-021-00679-1 10.1056/NEJMra0800885 10.1038/s41440-020-0532-z 10.1159/000381106 10.1371/journal.pone.0100801 10.1161/01.HYP.36.6.1072 10.5551/jat.31591 10.1136/bmj.j2376 10.1152/ajpendo.00378.2020 10.1007/s00775-014-1210-x 10.1016/j.bbadis.2014.05.022 10.1016/j.pharep.2015.05.004 10.1016/j.jchromb.2016.10.033 10.1016/j.metabol.2017.01.031 10.1253/circj.CJ-18-0082 10.1111/jdi.12982 10.1507/endocrj.EJ19-0053 10.1507/endocrj.EJ18-0127 10.1111/jdi.13207 10.1038/s41598-020-61463-8 10.1016/j.ijcard.2016.11.077 10.1053/j.ajkd.2008.12.034 10.1007/BF00280883 10.1016/S0021-9258(18)77283-9 10.1016/0009-2797(92)90093-Z 10.1074/jbc.274.8.4985 10.1371/journal.pone.0143560 10.1097/HJH.0000000000001204 10.4070/kcj.2019.0379 10.1016/j.mce.2012.04.013 10.1016/j.cjca.2020.02.066 10.1016/j.pathophys.2008.04.003 10.1038/nrendo.2017.56 10.1038/s41584-018-0004-x 10.1161/HYPERTENSIONAHA.120.16547 10.1097/HJH.0000000000001077 10.3390/ijms131115475 10.1016/S0022-5347(17)42404-9 10.1093/ajh/hpaa044 10.1111/jch.14153 10.1016/j.ejphar.2016.03.055 10.18502/rmm.v6i1.3919 10.1111/jch.13707 10.1016/j.atherosclerosis.2018.10.007
Hypertension Research : Official Journal of the Japanese ... Furuhashi M, Higashiura Y et. al.

Jun 12th, 2021 - Xanthine oxidoreductase (XOR), a rate-limiting and catalyzing enzyme of uric acid formation in purine metabolism, is involved in reactive oxygen species generation. Plasma XOR activity has been shown to be a novel metabolic biomarker related to ob...

Subsequent attempt tyrosine kinase inhibitor discontinuation in patients with chronic m...
https://doi.org/10.3390/ijms22115810
Hematological Oncology; Ureshino H, Kamachi K et. al.

Jun 12th, 2021 - Changes in lifestyle in developed countries have triggered the prevalence of obesity and type 2 diabetes mellitus (T2DM) in the latest years. Consequently, these metabolic diseases associated to insulin resistance, and the morbidity associated wit...

see more →

News  1,095 results

'Remarkable' Response to Diabetes Drug in Resistant Bipolar Depression
https://www.medscape.com/viewarticle/952548

Jun 6th, 2021 - Treating insulin resistance may improve treatment-resistant bipolar depression, early research suggests. In a randomized, placebo-controlled trial, treatment with the diabetes drug metformin reversed insulin resistance in 50% of patients, and this...

Metformin May Be Beneficial for Children With Obesity
https://www.medscape.com/viewarticle/946168

Feb 21st, 2021 - NEW YORK (Reuters Health) - Metformin had "modest" beneficial effects on weight and insulin resistance among obese young children in a systematic review. "Given the results of our study, metformin may be considered as an add-on therapy in children...

Major Depression Linked to Insulin Resistance
https://www.medscape.com/viewarticle/942251

Dec 7th, 2020 - Individuals experiencing a current episode of major depressive disorder (MDD) are significantly more likely to have insulin resistance (IR), new research shows. Investigators found patients with MDD were 51% more likely to have IR compared with th...

New Study Pinpoints How Mediterranean Diet Reduces Diabetes Risk
https://www.medscape.com/viewarticle/941649

Nov 25th, 2020 - The known reduction in the risk of type 2 diabetes associated with adoption of the Mediterranean diet appears specifically attributed to its beneficial effects on some key factors, a new study published online in JAMA Network Open reveals. While a...

Uncontrolled CVD Risk Factors in Teens Flag Organ Damage
https://www.staging.medscape.com/viewarticle/937969

Sep 23rd, 2020 - The presence of cardiovascular disease (CVD) risk factors in adolescence predicts target organ damage at a young age, supporting the concept that adult CVD has its origins in childhood, researchers say. "There are more and more obese children with...

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Patient Education  9 results see all →