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About 5,714 results

ALLMedicine™ Metabolic Acidosis Center

Research & Reviews  2,729 results

Randomized preclinical study of machine perfusion in vascularized composite allografts.
https://doi.org/10.1002/bjs.11921
The British Journal of Surgery References; Amin KR, Stone JP et. al.

Sep 18th, 2020 - Attempts to improve limb preservation for transplantation using ex vivo perfusion have yielded promising results. However, metabolic acidosis, aberrant perfusate biochemistry and significant perfusion-induced oedema are reported universally. Optim...

Lessons of the month: Pyroglutamic acidosis: long-term paracetamol and a high anion gap.
https://doi.org/10.7861/clinmed.2020-0363
Clinical Medicine (London, England); Trevor-Jones E, Hughes LT et. al.

Sep 16th, 2020 - An 84-year-old woman presented in extremis with confusion and Kussmaul respiration. She had a history of urosepsis, renal impairment and osteoarthrosis. The venous blood gas showed a marked metabolic acidosis with a high anion gap. Lactate and ket...

The effect of diabetic ketoacidosis (DKA) and its treatment on clot microstructure: Are...
https://doi.org/10.3233/CH-200957
Clinical Hemorheology and Microcirculation; Pillai S, Davies G et. al.

Sep 14th, 2020 - Diabetic ketoacidosis (DKA) is a medical emergency with a high mortality rate and is associated with severe metabolic acidosis and dehydration. DKA patients have an increased risk of arterial and venous thromboembolism, however little is known abo...

Veverimer: An Emerging Potential Treatment Option for Managing the Metabolic Acidosis o...
https://doi.org/10.1053/j.ajkd.2020.07.019
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation; Adrogué HJ, Madias NE

Sep 13th, 2020 - Sodium bicarbonate is the mainstay treatment of the metabolic acidosis of CKD but associated concerns center on administering sodium to patients with hypertension and sodium-retentive states. Veverimer (formerly TRC101) is a novel, non-absorbable ...

Sodium bicarbonate therapy for metabolic acidosis in critically ill patients: a survey ...
https://www.ncbi.nlm.nih.gov/pubmed/32900336
Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine; Serpa Neto A, Fujii T et. al.

Sep 9th, 2020 - To help shape the design of a future double blind placebo-controlled randomised clinical trial of bicarbonate therapy for metabolic acidosis, based on opinions of intensive care clinicians in Australia and New Zealand. An online survey was designe...

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Guidelines  4 results

Vibrio Cholerae - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK526099/

Nov 17th, 2018 - Cholera is a well-known disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. This potentially fatal diarrheal disease results in large volumes of watery stool, causing rapid dehydration that can progress to hyp...

Diagnosis and Treatment of Metabolic Acidosis in Patients with Chronic Kidney Disease -...
https://doi.org/10.1159/000490475
Kidney & Blood Pressure Research; Adamczak M, Masajtis-Zagajewska A et. al.

Jun 12th, 2018 - Metabolic acidosis is commonly found in patients with chronic kidney disease (CKD), and its causes are: impaired ammonia excretion, reduced tubular bicarbonate reabsorption and insufficient renal bicarbonate production in relation to the amount of...

Practical Approach to Detection and Management of Chronic Kidney Disease for the Primary Care Clinician
https://www.amjmed.com/article/S0002-9343(15)00855-4/pdf
The American Journal of Medicine; Vassalotti,J.,et al

Feb 1st, 2016 - A panel of internists and nephrologists developed this practical approach for the Kidney Disease Outcomes Quality Initiative to guide assessment and care of chronic kidney disease (CKD) by primary care clinicians. Chronic kidney disease is defined...

Prevention and treatment of protein energy wasting in chronic kidney disease patients: ...
https://doi.org/10.1038/ki.2013.147
Kidney International; Ikizler TA, Cano NJ et. al.

May 23rd, 2013 - Protein energy wasting (PEW) is common in patients with chronic kidney disease (CKD) and is associated with adverse clinical outcomes, especially in individuals receiving maintenance dialysis therapy. A multitude of factors can affect the nutritio...

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Drugs  97 results see all →

Clinicaltrials.gov  2,843 results

Randomized preclinical study of machine perfusion in vascularized composite allografts.
https://doi.org/10.1002/bjs.11921
The British Journal of Surgery References; Amin KR, Stone JP et. al.

Sep 18th, 2020 - Attempts to improve limb preservation for transplantation using ex vivo perfusion have yielded promising results. However, metabolic acidosis, aberrant perfusate biochemistry and significant perfusion-induced oedema are reported universally. Optim...

Lessons of the month: Pyroglutamic acidosis: long-term paracetamol and a high anion gap.
https://doi.org/10.7861/clinmed.2020-0363
Clinical Medicine (London, England); Trevor-Jones E, Hughes LT et. al.

Sep 16th, 2020 - An 84-year-old woman presented in extremis with confusion and Kussmaul respiration. She had a history of urosepsis, renal impairment and osteoarthrosis. The venous blood gas showed a marked metabolic acidosis with a high anion gap. Lactate and ket...

The effect of diabetic ketoacidosis (DKA) and its treatment on clot microstructure: Are...
https://doi.org/10.3233/CH-200957
Clinical Hemorheology and Microcirculation; Pillai S, Davies G et. al.

Sep 14th, 2020 - Diabetic ketoacidosis (DKA) is a medical emergency with a high mortality rate and is associated with severe metabolic acidosis and dehydration. DKA patients have an increased risk of arterial and venous thromboembolism, however little is known abo...

Veverimer: An Emerging Potential Treatment Option for Managing the Metabolic Acidosis o...
https://doi.org/10.1053/j.ajkd.2020.07.019
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation; Adrogué HJ, Madias NE

Sep 13th, 2020 - Sodium bicarbonate is the mainstay treatment of the metabolic acidosis of CKD but associated concerns center on administering sodium to patients with hypertension and sodium-retentive states. Veverimer (formerly TRC101) is a novel, non-absorbable ...

Sodium bicarbonate therapy for metabolic acidosis in critically ill patients: a survey ...
https://www.ncbi.nlm.nih.gov/pubmed/32900336
Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine; Serpa Neto A, Fujii T et. al.

Sep 9th, 2020 - To help shape the design of a future double blind placebo-controlled randomised clinical trial of bicarbonate therapy for metabolic acidosis, based on opinions of intensive care clinicians in Australia and New Zealand. An online survey was designe...

see more →

News  41 results

Phase III Success for CKD Complication Tx
https://www.medpagetoday.com/nephrology/generalnephrology/80747

Jun 27th, 2019 - The investigational drug veverimer was safe and effective for treating patients with metabolic acidosis from chronic kidney disease, according to phase III data. In a 40-week extension study, only 2% of those on veverimer had serious adverse event...

Cannabis May Help UC Patients: Gastro Endo News Report
https://www.medpagetoday.com/gastroenterology/generalgastroenterology/76868

Dec 12th, 2018 - Patients with moderate ulcerative colitis may benefit from cannabis, according to a new study that reported a decrease in disease activity index in patients who used the drug. A recent analysis found that consuming probiotics may contribute to sma...

Vibrio Cholerae - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK526099/

Nov 17th, 2018 - Cholera is a well-known disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. This potentially fatal diarrheal disease results in large volumes of watery stool, causing rapid dehydration that can progress to hyp...

Consent and DNR orders
https://www.mdedge.com/neurology/article/158675/business-medicine/consent-and-dnr-orders
S.Y. Tan, MD, JD

Feb 14th, 2018 - Question: Paramedics brought an unconscious 70-year-old man to a Florida hospital emergency department. The patient had the words “Do Not Resuscitate” tattooed onto his chest.

Correction: Altered mental status and an acid-base disturbance
https://www.mdedge.com/ccjm/article/132278/correction-altered-mental-status-and-acid-base-disturbance

Mar 1st, 2017 - In the article “ A patient with altered mental status and an acid-base disturbance ” (Mani S, Rutecki GW, Cleve Clin J Med 2017; 84:27–34), 2 errors occurred in Table 2. The corrected table appears with corrections shown in red: In addition, two s.

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