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About 16,253 results

ALLMedicine™ Metabolic Disorders Center

Research & Reviews  7,967 results

Biodistribution of transplanted hematopoietic precursor cells injected through differen...
https://doi.org/10.1089/hum.2019.191
Human Gene Therapy; Poletto E, Pinheiro CV et. al.

Feb 26th, 2021 - Hematopoietic stem cell transplantation has been studied for several decades now, mostly as a treatment for malignancies and hematological diseases but also for genetic metabolic disorders. Since many diseases that could be potentially treated wit...

Polysaccharides from fermented Momordica charantia L. with Lactobacillus plantarum NCU1...
https://doi.org/10.1039/d0fo02600j
Food & Function; Wen JJ, Li MZ et. al.

Feb 26th, 2021 - Obesity is a chronic disease characterized by overweight resulting from fat accumulation, along with disturbance of metabolism and gut microbiota. Fermentation, as a green processing method, is beneficial for improving the nutrition capacity of fo...

Maternal dietary supplementation with grape seed extract in reproductive hens increases...
https://doi.org/10.1371/journal.pone.0246750
PloS One; Grandhaye J, Lecompte F et. al.

Feb 25th, 2021 - Genetic selection in parental broiler breeders has increased their susceptibility to metabolic disorders and reproductive dysfunction. We have recently shown that maternal dietary grape seed extract (GSE) supplementation in hens improves fertility...

Tailor-made oligonucleotide-loaded lipid-polymer nanosystems designed for bone gene the...
https://doi.org/10.1007/s13346-021-00926-5 10.1007/s00198-018-4704-5 10.1146/annurev-med-052218-020620 10.1089/hum.2015.070 10.1093/nar/gkw236 10.1016/j.jim.2019.112674 10.1016/j.ejpb.2019.09.004 10.1186/s12951-018-0392-8 10.1016/j.ijpharm.2018.10.058 10.1016/j.msec.2019.110576 10.1039/c7bm01096f 10.1038/s41467-019-10112-4 10.1039/c6cs00636a 10.2147/ijn.s198353 10.1016/j.biomaterials.2008.12.013 10.1021/nn800275r 10.2147/IJN.S209325 10.1016/j.ijpharm.2012.05.008 10.1038/nprot.2008.221 10.1016/j.biomaterials.2015.07.048 10.1021/ja2084338 10.1021/acsnano.5b03876 10.1016/j.msec.2019.110252 10.1007/s11095-014-1381-8 10.1038/mtna.2014.61 10.1021/bm101482r 10.1016/j.jconrel.2010.08.010 10.1081/DIS-200027309 10.1016/j.ejpb.2018.03.005 10.1016/j.ijpharm.2019.05.078 10.1038/s41467-017-00600-w 10.1016/j.mimet.2019.03.017 10.1038/s41573-020-0075-7 10.1021/acs.langmuir.9b02692 10.1186/s13287-018-0995-x 10.1038/s41598-017-00466-4 10.1038/srep42840 10.1016/j.biomaterials.2015.10.042 10.2147/ijn.s36111 10.1002/smll.200901158 10.1016/j.biomaterials.2007.03.006 10.1007/s10439-019-02430-x
Drug Delivery and Translational Research; García-García P, Briffault E et. al.

Feb 24th, 2021 - Gene therapy has emerged as a tool for the treatment of systemic metabolic disorders as osteoporosis (OP). However, the design of a suitable vehicle able to efficiently load and release the genetic material on the target cells is still a challenge...

Diastolic dysfunction and impaired cardiac output reserve in dysmetabolic nonhuman prim...
https://doi.org/10.1016/j.jdiacomp.2021.107881
Journal of Diabetes and Its Complications; Wikstrom J, Liu Y et. al.

Feb 22nd, 2021 - Cardiorenal complications are common in patients with dysmetabolism and diabetes. The present study aimed to examine if a nonhuman primate (NHP) model with spontaneously developed metabolic disorder and diabetes develops similar complications to h...

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Guidelines  13 results

Psoriatic Arthritis and Diabetes Mellitus: A Narrative Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211212/
Rheumatology and Therapy; Dal Bello G

Apr 16th, 2020 - Psoriatic arthritis (PsA) is a chronic immune-mediated inflammatory spondyloarthropathy associated with psoriasis. PsA is frequently associated with metabolic disorders including, obesity, metabolic syndrome, and diabetes mellitus (DM). Type 2 DM ...

ACR Appropriateness Criteria® Acute Mental Status Change, Delirium, and New Onset Psych...
https://doi.org/10.1016/j.jacr.2019.02.024
Journal of the American College of Radiology : JACR; , Luttrull MD et. al.

May 5th, 2019 - Acute changes in mental status represent a broad collection of symptoms used to describe disorders in mentation and level of arousal, including the more narrowly defined diagnoses of delirium and psychosis. A wide range of precipitating factors ma...

Guidelines Insights: Hepatobiliary Cancers, Version 2.2019
https://jnccn.org/view/journals/jnccn/17/4/article-p302.xml
Benson,A.,et al

Mar 31st, 2019 - Incidence and mortality rates for cancer overall are declining, but both incidence and mortality rates for hepatocellular carcinoma (HCC) are increasing.1,2 Risk factors for development of HCC include infection with hepatitis B virus (HBV) and/or ...

Phosphodiesterase 5 inhibitors for pulmonary hypertension
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012621.pub2/full
Barnes,H.,et al

Jan 30th, 2019 - Pulmonary hypertension (PH) comprises a group of complex and heterogenous conditions, characterised by elevated pulmonary artery pressure, and which left untreated leads to right‐heart failure and death. PH includes World Health Organisation (WHO)...

Lycopene and tomato powder supplementation similarly inhibit high-fat diet induced obesity, inflammatory response, and associated metabolic disorders
https://www.ncbi.nlm.nih.gov/pubmed/28267248

Sep 5th, 2017 - SCOPE: Several studies have linked the high intake of lycopene or tomatoes products with lower risk for metabolic diseases. The aim of the present study was to evaluate and to compare the effect of lycopene and tomato powder on obesity-associated ...

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Clinicaltrials.gov  8,091 results

Biodistribution of transplanted hematopoietic precursor cells injected through differen...
https://doi.org/10.1089/hum.2019.191
Human Gene Therapy; Poletto E, Pinheiro CV et. al.

Feb 26th, 2021 - Hematopoietic stem cell transplantation has been studied for several decades now, mostly as a treatment for malignancies and hematological diseases but also for genetic metabolic disorders. Since many diseases that could be potentially treated wit...

Polysaccharides from fermented Momordica charantia L. with Lactobacillus plantarum NCU1...
https://doi.org/10.1039/d0fo02600j
Food & Function; Wen JJ, Li MZ et. al.

Feb 26th, 2021 - Obesity is a chronic disease characterized by overweight resulting from fat accumulation, along with disturbance of metabolism and gut microbiota. Fermentation, as a green processing method, is beneficial for improving the nutrition capacity of fo...

Maternal dietary supplementation with grape seed extract in reproductive hens increases...
https://doi.org/10.1371/journal.pone.0246750
PloS One; Grandhaye J, Lecompte F et. al.

Feb 25th, 2021 - Genetic selection in parental broiler breeders has increased their susceptibility to metabolic disorders and reproductive dysfunction. We have recently shown that maternal dietary grape seed extract (GSE) supplementation in hens improves fertility...

Tailor-made oligonucleotide-loaded lipid-polymer nanosystems designed for bone gene the...
https://doi.org/10.1007/s13346-021-00926-5 10.1007/s00198-018-4704-5 10.1146/annurev-med-052218-020620 10.1089/hum.2015.070 10.1093/nar/gkw236 10.1016/j.jim.2019.112674 10.1016/j.ejpb.2019.09.004 10.1186/s12951-018-0392-8 10.1016/j.ijpharm.2018.10.058 10.1016/j.msec.2019.110576 10.1039/c7bm01096f 10.1038/s41467-019-10112-4 10.1039/c6cs00636a 10.2147/ijn.s198353 10.1016/j.biomaterials.2008.12.013 10.1021/nn800275r 10.2147/IJN.S209325 10.1016/j.ijpharm.2012.05.008 10.1038/nprot.2008.221 10.1016/j.biomaterials.2015.07.048 10.1021/ja2084338 10.1021/acsnano.5b03876 10.1016/j.msec.2019.110252 10.1007/s11095-014-1381-8 10.1038/mtna.2014.61 10.1021/bm101482r 10.1016/j.jconrel.2010.08.010 10.1081/DIS-200027309 10.1016/j.ejpb.2018.03.005 10.1016/j.ijpharm.2019.05.078 10.1038/s41467-017-00600-w 10.1016/j.mimet.2019.03.017 10.1038/s41573-020-0075-7 10.1021/acs.langmuir.9b02692 10.1186/s13287-018-0995-x 10.1038/s41598-017-00466-4 10.1038/srep42840 10.1016/j.biomaterials.2015.10.042 10.2147/ijn.s36111 10.1002/smll.200901158 10.1016/j.biomaterials.2007.03.006 10.1007/s10439-019-02430-x
Drug Delivery and Translational Research; García-García P, Briffault E et. al.

Feb 24th, 2021 - Gene therapy has emerged as a tool for the treatment of systemic metabolic disorders as osteoporosis (OP). However, the design of a suitable vehicle able to efficiently load and release the genetic material on the target cells is still a challenge...

Diastolic dysfunction and impaired cardiac output reserve in dysmetabolic nonhuman prim...
https://doi.org/10.1016/j.jdiacomp.2021.107881
Journal of Diabetes and Its Complications; Wikstrom J, Liu Y et. al.

Feb 22nd, 2021 - Cardiorenal complications are common in patients with dysmetabolism and diabetes. The present study aimed to examine if a nonhuman primate (NHP) model with spontaneously developed metabolic disorder and diabetes develops similar complications to h...

see more →

News  157 results

Metabolic Disease Linked to Instability of the Gut Microbiome
https://www.staging.medscape.com/viewarticle/941175

Nov 17th, 2020 - NEW YORK (Reuters Health) - The gut microbiome appears to be largely stable over time in most people, but metabolic disorders such as fatty liver disease and diabetes are associated with increased microbial instability, according to new research. ...

Metabolic Disease Linked to Instability of the Gut Microbiome
https://www.medscape.com/viewarticle/941175

Nov 17th, 2020 - NEW YORK (Reuters Health) - The gut microbiome appears to be largely stable over time in most people, but metabolic disorders such as fatty liver disease and diabetes are associated with increased microbial instability, according to new research. ...

Psoriatic Arthritis and Diabetes Mellitus: A Narrative Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211212/
Rheumatology and Therapy; Dal Bello G

Apr 16th, 2020 - Psoriatic arthritis (PsA) is a chronic immune-mediated inflammatory spondyloarthropathy associated with psoriasis. PsA is frequently associated with metabolic disorders including, obesity, metabolic syndrome, and diabetes mellitus (DM). Type 2 DM ...

Ultra-Processed Foods Now Linked to Risk of Type 2 Diabetes
https://www.staging.medscape.com/viewarticle/922702

Dec 15th, 2019 - High consumption of so-called ultra-processed foods is associated with an increased risk of type 2 diabetes, independent of other risk factors including weight and nutritional quality of the diet, a new study indicates. The results suggest a possi...

Ultra-Processed Foods Now Linked to Risk of Type 2 Diabetes
https://www.medscape.com/viewarticle/922702

Dec 15th, 2019 - High consumption of so-called ultra-processed foods is associated with an increased risk of type 2 diabetes, independent of other risk factors including weight and nutritional quality of the diet, a new study indicates. The results suggest a possi...

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Patient Education  25 results see all →