ALLMedicine™ Necrobiosis Lipoidica Center

Jul 7th, 2021 - The Janus kinase-signal transducer and activator of transcription (JAK-STAT) intracellular signaling pathway is implicated in the pathogenesis of a number of inflammatory dermatoses. Clinical trials and other studies have demonstrated the efficacy...

Jun 22nd, 2021 - Necrobiosis lipoidica-associated cutaneous malignancy.|2021|Harvey JA,Severson KJ,Brumfiel CM,Patel MH,Butterfield RJ,|

Apr 21st, 2021 - Clinical and morphological features of necrobiosis lipoidica.|2021|Severson KJ,Costello CM,Brumfiel CM,Patel MH,Butterfield RJ,|

Apr 8th, 2021 - Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown aetiology. Randomized controlled studies are not available due to it being an orphan disease. We evaluated patients in 2 dermatological centres to cluster data about epidemiolo...

Mar 23rd, 2021 - Necrobiosis lipoidica is a granulomatous skin condition commonly associated with diabetes. When associated with diabetes mellitus, the name expands to necrobiosis lipoidica diabeticorum (NLD). In these patients, this rare condition has an incidenc...

Mar 19th, 2020 - This is an open-label study that will evaluate the safety of PCS499 for the treatment of necrobiosis lipoidica (NL) and will inform the design of future studies. Approximately 12 NL patients (6-9 patients without ulceration and 3-6 patients with u...

Jan 7th, 2020 - DM and Diabetic Skin Disease Diabetes mellitus carries with it the risk for skin diseases specific to the diabetic disease process, such as increased risk for bacterial and fungal infections, venous stasis, pruritus (secondary to poor circulation).

Sep 19th, 2019 - In addition to this change in antibiotic coverage, the patient’s medical oncologist tapered the patient’s immunosuppression considerably. The patient subsequently completed 12 months of therapy with clarithromycin, moxifloxacin, and rifabutin star.

Apr 22nd, 2019 - Sarcoidosis is a systemic noncaseating granuloma­tous disease of unknown etiology. The skin is the second most common location for disease mani­festation following the lungs.

Jan 9th, 2019 - Clinically, NL presents with asymptomatic, well-circumscribed, violaceous papules and nodules that coalesce into plaques on the lower extremities, face, or trunk. The plaques have a central red-brown hue that progressively becomes more yellow and.

Jan 8th, 2018 - The Diagnosis: Necrobiotic Xanthogranuloma A 4-mm punch biopsy was performed for routine stain with hematoxylin and eosin. The differential diagnosis included sarcoidosis, necrobiosis lipoidica, xanthoma disseminatum, and multicentric reticulohist.