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About 15,295 results

ALLMedicine™ Acidosis Center

Research & Reviews  5,066 results

Severe hypophosphatemia as the initial presentation of renal Fanconi's syndrome and dis...
https://doi.org/10.1159/000527931
Kidney & Blood Pressure Research; Wu Y, Ma T et. al.

Nov 23rd, 2022 - Zoledronic acid (ZA) is a widely used bisphosphonate compound for the prevention of skeletal metastasis-associated osteolysis and treatment of post-menopause osteoporosis. Acute kidney injury is one of the commonly described renal complications. E...

Percutaneous sclerotherapy for head and neck lymphatic malformations in neonates and in...
https://doi.org/10.1136/jnis-2022-019516
Journal of Neurointerventional Surgery; Caton MT, Duvvuri M et. al.

Nov 23rd, 2022 - Percutaneous sclerotherapy is an effective treatment for lymphatic malformations (LM) of the head and neck in adults. The purpose of this study was to examine the indications and efficacy of sclerotherapy for head/neck LM in the neonate and infant...

Prenatal phenotype of FBXL4 associated encephalomyopathic mitochondrial DNA depletion s...
https://doi.org/10.1002/pd.6272
Prenatal Diagnosis; Saini DN, Venkatapuram V et. al.

Nov 22nd, 2022 - FBXL4 associated encephalomyopathic mitochondrial DNA depletion syndrome-13 (MTDPS13) is a rare genetic disorder characterized by early neonatal onset of encephalopathy, seizures, lactic acidosis, hypotonia, dysmorphism and severe global developme...

Crosstalk between tumor acidosis, p53, and extracellular matrix regulates pancreatic ca...
https://doi.org/10.1002/ijc.34367
International Journal of Cancer; Czaplinska D, Ialchina R et. al.

Nov 22nd, 2022 - Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy with minimal treatment options and a global rise in prevalence. PDAC is characterized by frequent driver mutations including KRAS and TP53 (p53), and a dense, acidic tum...

Sodium Bicarbonate Administration is Associated with Improved Survival in Asystolic and...
https://doi.org/10.1016/j.resuscitation.2022.11.007
Resuscitation Niederberger SM, Crowe RP et. al.

Nov 21st, 2022 - Sodium bicarbonate ("bicarb") administration in out-of-hospital cardiac arrest (OHCA) is intended to counteract acidosis, although there is limited clinical evidence to support its routine administration. We sought to analyze the association of bi...

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Guidelines  2 results

Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critical...
https://doi.org/10.1097/CCM.0000000000002027
Critical Care Medicine; Murray MJ, DeBlock H et. al.

Oct 19th, 2016 - To update the 2002 version of "Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient." A Task Force comprising 17 members of the Society of Critical Medicine with particular expertise in the use of n...

Evaluation and management of small-bowel obstruction: an Eastern Association for the Su...
https://doi.org/10.1097/TA.0b013e31827019de
The Journal of Trauma and Acute Care Surgery; Maung AA, Johnson DC et. al.

Dec 27th, 2012 - Small-bowel obstruction (SBO) represents as many as 16% of surgical admissions and more than 300,000 operations annually in the United States. The optimal strategies for the diagnosis and management of SBO continue to evolve secondary to advances ...

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Drugs  208 results see all →

Clinicaltrials.gov  472 results

Cancer in Inherited Bone Marrow Failure Syndromes
https://clinicaltrials.gov/ct2/show/NCT00027274

Oct 14th, 2022 - Background: A prospective cohort of Inherited Bone Marrow Failure Syndrome (IBMFS) will provide new information regarding cancer rates and types in these disorders. Pathogenic variant(s) in IBMFS genes are relevant to carcinogenesis in sporadic ca...

Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis
https://clinicaltrials.gov/ct2/show/NCT03710291

Oct 14th, 2022 - This is a randomized, double-blind, placebo-controlled trial. Eligible subjects will be randomized in a 1:1 ratio to TRC101 or placebo. The primary endpoint of the study will be progression of renal disease, defined by time to first occurrence of ...

PRone positioN in Patients With spontanEous ventiLation and Acute Hypoxemic respIratory FailurE
https://clinicaltrials.gov/ct2/show/NCT04142736

Oct 13th, 2022 - The investigators intend to recruit acute hypoxemic respiratory failure patients with a respiratory rate of more than 25 breaths per minute, SpO2 < 94% and FiO2 of at least 40% or more by either Venturi facemask, HFNC, or NIV/CPAP and, absence of ...

The Genetics of Severe Asthma in Children
https://clinicaltrials.gov/ct2/show/NCT01238432

Oct 12th, 2022 - Our primary outcome measure is the development of a near fatal asthma exacerbation. Secondary outcome measures will include the duration of continuously nebulized ADRβ2 agonist therapy and the duration of IV ADRβ2 agonist therapy. Children will be...

Evaluation of Haemodynamic in Neonates Treated With Hypothermia"
https://clinicaltrials.gov/ct2/show/NCT05574855

Oct 12th, 2022 - Impact of hypoxia on the cardiovascular system Transitory hypoxia of the myocardium (and its resultant dysfunction), which may, but not necessarily, present clinically, occurs in two thirds of neonates born with perinatal asphyxia. There is no dou...

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News  365 results

Nivolumab/Ipilimumab Plus CBM588 Generates Superior Efficacy in Metastatic RCC
https://www.onclive.com/view/nivolumab-ipilimumab-plus-cbm588-generates-superior-efficacy-in-metastatic-rcc

Nov 7th, 2022 - The addition of CBM588, a live probiotic comprised primarily of Clostridium butyricum, to the combination of nivolumab (Opdivo) and ipilimumab (Yervoy) produced superior response rates and a progression-free survival (PFS) benefit vs nivolumab plu...

FDA Expands Tenofovir Alafenamide (Vemlidy ) Use to Adolescents With Chronic HBV
https://www.medscape.com/viewarticle/983596

Nov 4th, 2022 - The US Food and Drug Administration (FDA) has expanded the indication for tenofovir alafenamide (Vemlidy) to children aged 12 years and older with chronic hepatitis B virus (HBV) infection with compensated liver disease, Gilead Sciences has announ...

Euthyroid Sick Syndrome Hits Many With Diabetic Ketosis 
https://www.medscape.com/viewarticle/978764

Aug 5th, 2022 - Researchers published the study covered in this summary on Research Square as a preprint that has not yet been peer reviewed. Key Takeaways The results showed a 58% prevalence of euthyroid sick syndrome (ESS) in 396 adults hospitalized with diabet...

SARS-CoV-2: A Novel Precipitant of Ischemic Priapism
https://www.mdedge.com/fedprac/article/256292/covid-19-updates/sars-cov-2-novel-precipitant-ischemic-priapism
Lorraine Mascarenhas, MD, Danielle Hron, MD et. al.

Jul 15th, 2022 - Priapism is a disorder that occurs when the penis maintains a prolonged erection in the absence of appropriate stimulation. The disorder is typically divided into subgroups based on arterial flow: low flow (ischemic) and high flow (nonischemic).

Pruritus and pitting edema
https://www.mdedge.com/type-2-diabetes-challenge-center/article/255400/type-2-diabetes/pruritus-and-pitting-edema

Jun 13th, 2022 - The 2020 Kidney Disease Improving Global Outcomes (KDIGO) diabetes management in CKD guideline states that most patients with diabetic nephropathy and an eGFR ≥ 30 mL/min/1. 73 m 2 benefit from treatment with both metformin and a sodium-glucose cot.

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Patient Education  5 results see all →