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About 973 results

ALLMedicine™ Calciphylaxis Center

Research & Reviews  319 results

Better Evidence and Translation for Calciphylaxis
https://clinicaltrials.gov/ct2/show/NCT05018221

Mar 3rd, 2023 - BEAT-Calci is a randomized, adaptive, multi-center, platform trial that will evaluate multiple interventions, across several domains of therapeutic care. The objective of the study is to establish high-quality evidence on the effect of a range of ...

Therapeutic evaluation of calciphylaxis by transcutaneous oxygen tension measurement in...
https://doi.org/10.1684/ejd.2022.4361
European Journal of Dermatology : EJD; Nishihara K, Shiraishi K et. al.

Mar 2nd, 2023 - Therapeutic evaluation of calciphylaxis by transcutaneous oxygen tension measurement in a case treated with a combined regimen including sodium thiosulphate|2023|Nishihara K,Shiraishi K,Utsunomiya R,Tohyama M,Sayama K,|

An unexpected case of non-uremic calciphylaxis in a patient with multiple risk factors.
https://doi.org/10.5070/D328659739
Dermatology Online Journal; Nugent S, Karaisz F et. al.

Feb 23rd, 2023 - A 58-year-old woman with a history of morbid obesity, asthma, and prior warfarin use presented to the hospital with shortness of breath and a three-month history of painful, ulcerated ulcers with retiform purpura of her bilateral distal extremitie...

Rheopheresis as Adjuvant Treatment of Calciphylaxis
https://clinicaltrials.gov/ct2/show/NCT04654000

Feb 16th, 2023 - Calciphylaxis, also known as uremic calcifying arteriolopathy (UCA), is a rare disease that causes painful ischemic skin lesions due to microvascular calcification and thrombosis of the dermis and subcutaneous adipose tissue. Patients with end-sta...

Characterizing the burden of calciphylaxis: a qualitative analysis.
https://doi.org/10.1093/ced/llac118
Clinical and Experimental Dermatology; Singh R, McCain S et. al.

Feb 11th, 2023 - Calciphylaxis is a debilitating disease associated with high mortality and morbidity secondary to pain, nonhealing wounds and frequent hospital admissions. We qualitatively assessed the burden of calciphylaxis on patient quality of life through se...

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Clinicaltrials.gov  27 results

Better Evidence and Translation for Calciphylaxis
https://clinicaltrials.gov/ct2/show/NCT05018221

Mar 3rd, 2023 - BEAT-Calci is a randomized, adaptive, multi-center, platform trial that will evaluate multiple interventions, across several domains of therapeutic care. The objective of the study is to establish high-quality evidence on the effect of a range of ...

Rheopheresis as Adjuvant Treatment of Calciphylaxis
https://clinicaltrials.gov/ct2/show/NCT04654000

Feb 16th, 2023 - Calciphylaxis, also known as uremic calcifying arteriolopathy (UCA), is a rare disease that causes painful ischemic skin lesions due to microvascular calcification and thrombosis of the dermis and subcutaneous adipose tissue. Patients with end-sta...

Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation
https://clinicaltrials.gov/ct2/show/NCT05679024

Jan 10th, 2023 - Background and rationale: Atrial fibrillation (AF) is common (15-30%) in patients with chronic kidney disease (CKD) and AF prevalence increases with severity of CKD. In late stages of CKD, randomized control trials (RCT) of both efficacy and safet...

Retrospective Study Evaluating the Contribution of Rheopheresis in the Treatment of Uremic Calciphylaxis (RHEO-CUA)
https://clinicaltrials.gov/ct2/show/NCT05633121

Dec 12th, 2022 - Calcifying uremic arteriolopathy (or uremic calciphylaxis) is a rare disease (prevalence <1% of dialysis patients), but the prognosis is often catastrophic. The main non-modifiable risk factors are age, female gender, diabetes, obesity and length ...

Phase 3 Study of SNF472 for Calciphylaxis
https://clinicaltrials.gov/ct2/show/NCT04195906

Aug 30th, 2022 - The formation and growth of calcified deposits in arterioles and other small blood vessels appears to be fundamental to the development of CUA especially in end stage renal disease patients. This phase 3 double-blind, randomized, placebo-controlle...

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News  35 results

Tender Nonhealing Lesion on the Leg
https://www.mdedge.com/dermatology/article/258269/dermatopathology/tender-nonhealing-lesion-leg
Austinn C. Miller, MD, Mojahed Mohammad K. Shalabi, MD et. al.

Sep 28th, 2022 - The Diagnosis: Calciphylaxis Calciphylaxis is a rare life-threatening condition that most often is seen in patients with end-stage renal disease at a rate of 35 per 10,000 chronic dialysis patients. 1 It less commonly has been described in nonuremi.

Retiform Purpura on the Legs
https://www.mdedge.com/dermatology/article/254484/dermatopathology/retiform-purpura-legs
Mark C. Marchitto, MD, Liesl Grenier, MD et. al.

May 10th, 2022 - The Diagnosis: Calciphylaxis Histopathology revealed epidermal and dermal necrosis, a perivascular neutrophilic infiltrate, and scattered microcalcifications within small- and medium-sized subcutaneous vessels, consistent with a diagnosis of calci.

Dystrophic Calcinosis Cutis: Treatment With Intravenous Sodium Thiosulfate
https://www.mdedge.com/dermatology/article/228543/rare-diseases/dystrophic-calcinosis-cutis-treatment-intravenous-sodium
Ahmed H. Badawi, MD, PhD, Vikas Patel, MD et. al.

Sep 15th, 2020 - To the Editor: Severe dystrophic calcinosis cutis is a debilitating disease with no universally accepted therapeutic options. This case demonstrates the benefit of intravenous (IV) sodium thiosulfate in alleviating the calcified lesions as well as.

When to suspect calciphylaxis and what to do about it
https://www.mdedge.com/dermatology/article/220504/medical-dermatology/when-suspect-calciphylaxis-and-what-do-about-it
Bruce Jancin

Apr 9th, 2020 - If the shoe fits a presumptive clinical diagnosis of calciphylaxis, wear it – and don’t assume that ordering imaging studies or histology will make for a better fit or is even necessary. Dr.

An Unusual Presentation of Calciphylaxis
https://www.mdedge.com/dermatology/article/219998/rare-diseases/unusual-presentation-calciphylaxis/page/0/1?channel=44

Apr 1st, 2020 - The pathogenesis of calciphylaxis is not well understood; however, some researchers suggest that an imbalance in calcium-phosphate homeostasis may lead to calciphylaxis; that is, elevated calcium and phosphate levels exceed their solubility and de.

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Patient Education  8 results see all →