×
About 4,165 results

ALLMedicine™ Familial Hypercholesterolemia Center

Research & Reviews  1,057 results

Pediatric Drug Development Studies for Familial Hypercholesterolemia Submitted to the U...
https://doi.org/10.1002/jcph.1973
Journal of Clinical Pharmacology; Park K, Vishnevetskaya K et. al.

Sep 26th, 2021 - Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder of lipoprotein metabolism that leads to an increased risk of developing atherosclerosis and coronary artery disease. Hypercholesterolemia in pediatric patients is typical...

Hemoglobin concentration, hematocrit and red blood cell count predict major adverse car...
https://doi.org/10.1016/j.atherosclerosis.2021.09.015
Atherosclerosis Paquette M, Bernard S et. al.

Sep 22nd, 2021 - Familial hypercholesterolemia (FH) is a genetic disease associated with an important risk of premature and recurrent atherosclerotic cardiovascular disease (ASCVD). Red blood cell (RBC) parameters such as cell count and hematocrit (HCT) have previ...

Familial Hypercholesterolemia in Patients with Acute Coronary Syndrome: Genetic Insight...
https://doi.org/10.5551/jat.62989
Journal of Atherosclerosis and Thrombosis; Harada-Shiba M, Ako J et. al.

Sep 17th, 2021 - Genetic testing can provide a definitive diagnosis of familial hypercholesterolemia (FH). However, accessibility of genetic testing may be limited in certain countries where it is not considered "standard of care," including Japan. In addition, mu...

The effects of cholesterol accumulation on Achilles tendon biomechanics: A cross-sectio...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445482
PloS One; Squier K, Scott A et. al.

Sep 17th, 2021 - Familial hypercholesterolemia, a common genetic metabolic disorder characterized by high cholesterol levels, is involved in the development of atherosclerosis and other preventable diseases. Familial hypercholesterolemia can also cause tendinous a...

Loss of statin treatment years during pregnancy and breastfeeding periods in women with...
https://doi.org/10.1016/j.atherosclerosis.2021.09.003
Atherosclerosis Klevmoen M, Bogsrud MP et. al.

Sep 15th, 2021 - Women with heterozygous familial hypercholesterolemia (FH) are recommended to initiate statin treatment at the same age as men (from 8 to 10 years of age). However, statins are contraindicated when pregnancy is planned, during pregnancy and breast...

see more →

Guidelines  2 results

Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Up...
https://doi.org/10.1016/j.cjca.2018.09.005
The Canadian Journal of Cardiology; Brunham LR, Ruel I et. al.

Dec 12th, 2018 - Familial hypercholesterolemia (FH) is the most common monogenic disorder causing premature atherosclerotic cardiovascular disease. It affects 1 in 250 individuals worldwide, and of the approximately 145,000 Canadians estimated to have FH, most are...

Familial hypercholesterolemia.
https://www.ncbi.nlm.nih.gov/pubmed/24335046
Journal of Atherosclerosis and Thrombosis; Teramoto T, Sasaki J et. al.

Dec 18th, 2013 - Familial hypercholesterolemia.|2013|Teramoto T,Sasaki J,Ishibashi S,Birou S,Daida H,|diagnosis,etiology,prevention & control,diagnosis,etiology,prevention & control,diagnosis,prevention & control,

see more →

Drugs  335 results see all →

News  272 results

Study Sheds Light on LDL-C Trajectories in Childhood, Supports Screening Advice
https://www.medscape.com/viewarticle/955032

Jul 21st, 2021 - NEW YORK (Reuters Health) - New data from the International Childhood Cardiovascular Cohort (i3C) consortium shed light on trajectories of low-density lipoprotein cholesterol (LDL-C) in childhood and on the possible prevalence of heterozygous fami...

Real-world PCSK9i Data in FH Reveal Conundrum of Reimbursement
https://www.medscape.com/viewarticle/953408

Jun 18th, 2021 - Patients with familial hypercholesterolemia (FH), particularly those with heterozygous FH, see their low-density-lipoprotein (LDL) cholesterol levels slashed with evolocumab (Repatha) and maintained out to 2 years, suggests data from the HEYMANS r...

Limited-Variant Screening Tests Often Miss Familial Hypercholesterolemia
https://www.medscape.com/viewarticle/952069

May 31st, 2021 - NEW YORK (Reuters Health) - Two-thirds of cases of familial hypercholesterolemia (FH) would be missed by relying on array-based genetic tests that screen for only a limited number of variants, according to a new study. "Negative findings on a limi...

An Expert's Guide to Managing Familial Hypercholesterolemia
https://www.medscape.com/viewarticle/948546

Apr 21st, 2021 - This transcript has been edited for clarity. Hi. I'm Seth Baum, a preventive cardiologist and clinical lipidologist in Boca Raton, Florida. I'm also the past president of the American Society for Preventive Cardiology and on the faculty at the Flo...

An Expert's Guide to Managing Familial Hypercholesterolemia
https://www.medscape.com/viewarticle/948546?src=sapfe

Apr 21st, 2021 - This transcript has been edited for clarity. Hi. I'm Seth Baum, a preventive cardiologist and clinical lipidologist in Boca Raton, Florida. I'm also the past president of the American Society for Preventive Cardiology and on the faculty at the Flo...

see more →