ALLMedicine™ Hypercalcemia Center

Mar 28th, 2023 - Familial hypocalciuric hypercalcemia type 2 (FHH2) and autosomal dominant hypocalcemia type 2 (ADH2) are due to loss- and gain-of-function mutations, respectively, of the GNA11 gene that encodes the G protein subunit Gα11, a signaling partner of t...

Mar 24th, 2023 - Prevalence and Clinicopathologic Characteristics of Hypercalcemia in Patients With Cholangiocarcinoma.|2023|Konstantinidou E,Maurer JR,Reyes SL,Baiev I,Stanton JR,|

Mar 23rd, 2023 - The Case | Hematuria and hypercalcemia in a kidney transplant recipient.|2023|Banjongjit A,Wuttiputhanun T,Vanichanan J,Ueaphongsukkit T,Iampenkhae K,|diagnosis,etiology,diagnosis,etiology,adverse effects,

Mar 21st, 2023 - Practice Essentials Renal cell carcinoma (see the image below) is the most common type of kidney cancer in adults. It accounts for approximately 85% of neoplasms arising from the kidney. [1] Typical renal cell carcinoma. CT scan obtained before co...

Mar 21st, 2023 - Parathyroid cancer (PC) is a rare endocrine neoplasm with high mortality. While surgery is the treatment for patients with the disease, recurrence rates are high, and patients usually succumb to severe hypercalcemia. There is no effective systemic...

Jan 19th, 2019 - Adult T-cell leukemia-lymphoma (ATL) is a distinct mature T-cell malignancy caused by chronic infection with human T-lymphotropic virus type 1 with diverse clinical features and prognosis. ATL remains a challenging disease as a result of its diver...

Feb 12th, 2017 - Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone marrow causing skeletal damage, a hallmark of multiple myeloma. Other MM-r...

Oct 12th, 2014 - Hydroelectrolytic disorders are one of the most common metabolic complications in cancer patients. Although often metabolic alterations affecting various ions are part of the manifestations of the oncological disease, even in the form of paraneopl...

Vitamin D is a fat-soluble vitamin that is found in some animal food products and is also synthesized in the human body via exposure to the sun. Toxicity of vitamin D leads to hypercalcemia and imbalance in the regulation of bone metabolism; the r...

Mar 9th, 2023 - Primary hyperparathyroidism (PHPT) is known to affect the kidney and skeletal system, however, recent data have suggested that patients can also exhibit an increased cardiovascular risk and metabolic abnormalities Primary hyperparathyroidism (PHPT...

Feb 28th, 2023 - Multiple myeloma (MM) is the second most common hematological tumor after non-Hodgkin's lymphoma. The tumor cells originate from plasma cells in the blood pulp and are classified as plasma cells blood myeloma plasmacytomas by the WHO Tumor. It is ...

Feb 24th, 2023 - Multiple myeloma is a malignant plasma cell disorder characterized by osteolytic lesions, increased susceptibility to infections, hypercalcemia, and renal failure. Talquetamab is a humanized immunoglobulin G4 proline, alanine, alanine (IgG4PAA) bi...

Feb 24th, 2023 - Osteoporosis and osteopenia are chronic diseases disproportionately affecting the elderly. In the United States, the prevalence of osteoporosis is projected to increase from 10 million in 2005 to 14 million in 2025, due to population aging. Simila...

Feb 21st, 2023 - Background: Smoldering multiple myeloma (SMM) is a precursor condition to MM defined by the clinical parameters of M-protein >=3.0 g/dL or bone marrow plasma cells >=10%, and absence of end organ disease. Patients with high-risk SMM have a risk of...

Mar 17th, 2023 - The history and findings in this case are suggestive of small cell carcinoma of the prostate (SCCP). SCCP is a rare and aggressive cancer that comprises 1%–5% of all prostate cancers (if mixed cases with adenocarcinoma are included).

Feb 6th, 2023 - In adults with prediabetes, vitamin D helped decrease the risk that these individuals would develop diabetes, suggests a meta-analysis of three trials. Results of the analysis, led by Anastassios G.

Feb 6th, 2023 - Daily higher-dose vitamin D supplementation may help stave off diabetes in an at-risk population, researchers reported. In a meta-analysis of three randomized clinical trials, vitamin D reduced the risk for type 2 diabetes by 15% in people with pr...

Dec 29th, 2022 - New insight into why many cancer survivors refuse vaccination against human papillomavirus. (Cancer) The cost of treating metastatic prostate cancer rose sharply over the past 15 years, largely because of increased use of newer, more expensive dru...

Dec 27th, 2022 - The Endocrine Society released new guidelines for treating hypercalcemia of malignancy in adults. (The Journal of Clinical Endocrinology & Metabolism) Childhood cancer survivors -- especially females -- may carry an increased risk for fractures. (...