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About 110 results

ALLMedicine™ Hypobetalipoproteinemia Center

Research & Reviews  38 results

HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism
https://clinicaltrials.gov/ct2/show/NCT02354079

Mar 9th, 2022 - The goal is to recruit 400 subjects: 200 adult subjects with familial hypobetalipoproteinemia (FHBL) (index cases) plus 200 additional related subjects in at least 10 large informative FHBL families, in which there is no known mutation in FHBL gen...

Lipid Profile (Triglycerides)
https://emedicine.medscape.com/article/2074115-print

Nov 3rd, 2021 - Triglycerides are lipid compounds composed of a glycerol esterified to 3 fatty acid chains of varying length and composition. These fatty acid chains can be saturated or unsaturated, and the chemical composition of each chain is different. Each ch...

Lipid Profile (Triglycerides)
https://emedicine.medscape.com/article/2074115-overview

Nov 3rd, 2021 - Reference Range Triglycerides are lipid compounds composed of a glycerol esterified to 3 fatty acid chains of varying length and composition. These fatty acid chains can be saturated or unsaturated, and the chemical composition of each chain is di...

Prevalence of fAmilial hypobetalipopRoTeinemIa in psychiaTrIc pOpulatioN (PARTITION)
https://clinicaltrials.gov/ct2/show/NCT03549637

Sep 16th, 2021 - Some forms of hypobetalipoproteinemia (HBL) are associated with a longevity syndrome and cardiovascular protection due to prolonged exposure to low levels of LDL-C. However, while LDL-C reduction has been studied extensively for its beneficial eff...

Low LDL Cholesterol (Hypobetalipoproteinemia)
https://emedicine.medscape.com/article/121975-overview

Aug 19th, 2021 - Practice Essentials Abetalipoproteinemia (ABL) and familial hypobetalipoproteinemia (FHBL) are relatively uncommon inherited disorders of lipoprotein metabolism that cause low cholesterol levels. [1] Although persons whose low-density lipoprotein ...

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Clinicaltrials.gov  3 results

HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism
https://clinicaltrials.gov/ct2/show/NCT02354079

Mar 9th, 2022 - The goal is to recruit 400 subjects: 200 adult subjects with familial hypobetalipoproteinemia (FHBL) (index cases) plus 200 additional related subjects in at least 10 large informative FHBL families, in which there is no known mutation in FHBL gen...

Prevalence of fAmilial hypobetalipopRoTeinemIa in psychiaTrIc pOpulatioN (PARTITION)
https://clinicaltrials.gov/ct2/show/NCT03549637

Sep 16th, 2021 - Some forms of hypobetalipoproteinemia (HBL) are associated with a longevity syndrome and cardiovascular protection due to prolonged exposure to low levels of LDL-C. However, while LDL-C reduction has been studied extensively for its beneficial eff...

Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration
https://clinicaltrials.gov/ct2/show/NCT00362180

Oct 21st, 2016 - This was a randomized, double-blind, placebo-controlled study to measure the effect of treatment with mipomersen on liver triglyceride (TG) content in patients with varying degrees of hyperlipidemia and risk for hepatic steatosis. The original stu...

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News  3 results

Lean Patients, Yet Still at Risk for Fatty Liver Disease
https://www.medscape.com/viewarticle/868783_4

Sep 20th, 2016 - Defining an Effective Management Strategy When it comes to managing these patients, awareness and case recognition are crucial. An initial step in the evaluation of lean patients with presumed NAFLD is to rule out metabolic causes of fatty liver. ...

The Emerging Epidemic of Nonalcoholic Fatty Liver Disease
https://www.medscape.com/viewarticle/735888_1

Jan 21st, 2011 - The Spectrum of Nonalcoholic Fatty Liver Nonalcoholic fatty liver disease (NAFLD) includes the clinical-pathologic entities of steatosis (nonalcoholic fatty liver, or NAFL) and nonalcoholic steatohepatitis (NASH) with or without fibrosis and cirrh...

Could the Genetic Cause of an Uncommon Lipidemia Serve as a New Anti-Cholesterol Target?
https://www.medscape.com/viewarticle/733572

Dec 10th, 2010 - Exome Sequencing, ANGPTL3 Mutations, and Familial Combined Hypolipidemia Musunuru K, Pirruccello JP, Do R, et al N Engl J Med. 2010 Oct 13 [Epub ahead of print] Summary Familial hypobetalipoproteinemia (FHBL) is an uncommon inherited disorder char...

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