About 3,768 results

ALLMedicine™ Metabolic Acidosis Center

Research & Reviews  1,321 results

Valproate Toxicity Workup

Oct 21st, 2021 - Approach Considerations Determination of the valproate (valproic acid [VPA]) level is obviously warranted. Reviews have shown that nearly 20% of VPA overdose patients may present with initial VPA concentrations that are in the therapeutic range, o...

Antenatal Bartter syndrome: a new compound heterozygous mutation in exon 2 of KCNJ1 gene.
BMJ Case Reports; Mani S, Nair J et. al.

Oct 20th, 2021 - A 30+6/7-week infant was born by vaginal delivery to a 21-year-old primigravida with pregnancy complicated by polyhydramnios. The infant developed polyuria and significant weight loss in the first 2 weeks of life despite appropriate fluid manageme...

Renal haemofiltration prevents metabolic acidosis and reduces inflammation during normo...
Artificial Organs; Stone JP, Amin KR et. al.

Oct 19th, 2021 - Recent experimental evidence suggests normothermic machine perfusion of the vascularised composite allograft (VCA) results in improved preservation compared to static cold storage, with less reperfusion injury in the immediate post-operative perio...

Novel cubosome based system for ocular delivery of acetazolamide.
Drug Delivery; Teba HE, Khalil IA et. al.

Oct 19th, 2021 - Acetazolamide is the drug of choice for glaucoma treatment in an emergency. However, it is not available in any topical formulation and it is available only as systemic tablets. Despite its efficiency as a drug in decreasing intraocular pressure, ...

see more →

Guidelines  1 results

Evaluation and management of small-bowel obstruction: an Eastern Association for the Su...
The Journal of Trauma and Acute Care Surgery; Maung AA, Johnson DC et. al.

Dec 27th, 2012 - Small-bowel obstruction (SBO) represents as many as 16% of surgical admissions and more than 300,000 operations annually in the United States. The optimal strategies for the diagnosis and management of SBO continue to evolve secondary to advances ...

see more →

Drugs  72 results see all →

Clinicaltrials.gov  26 results

External Validation of Delirium Prediction Models for Intensive Care Patients

Oct 19th, 2021 - Adult ICU patients admitted to the participating ICUs in the Region Zealand are included according to eligibility. Eligible patients will be assessed with E-PREDELIRIC at admission to the ICU and PREDELIRIC 24h after admission to the ICU. Patients...

Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities

Aug 17th, 2021 - Continuous fetal heart rate tracing is part of the standard practice during intrapartum obstetric management. The goal of fetal heart rate monitoring is to identify early signs of fetal distress during labor, initiate effective interventions to im...

The Threshold of Serum Anion Gap as a Screening Tool for Organic Acidosis

Jul 26th, 2021 - BACKGROUND: The urea & electrolyte (U&E) panel is a common blood test that is often performed for any ill patients in a hospital. Evaluation of this panel can reveal serious underlying acid-base disturbances, often a harbinger of further haemodyna...

Skin Autofluorescence as a Risk Marker in People Receiving Dialysis.

Apr 28th, 2021 - STUDY BACKGROUND Chronic kidney disease (CKD) is a global public health problem and is associated with multiple adverse outcomes including reduced survival, especially in people requiring renal replacement therapy (peritoneal dialysis (PD), haemod...

Ketamine Infusion as Sedative Analgesic in Severe ARDS

Mar 26th, 2021 - According to the 2018 Clinical Practice Guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the intensive care unit (ICU), nonbenzodiazepine sedatives (such as p...

see more →

News  87 results

Comparison of Adverse Events With Vancomycin Diluted in Normal Saline vs Dextrose 5%
Robert C. Ross, PharmD, Bridgette A. Kelly, PharmD et. al.

Oct 8th, 2021 - Vancomycin is a widely used IV antibiotic due to its broad-spectrum of activity, bactericidal nature, and low rates of resistance; however, adverse effects (AEs), including nephrotoxicity, are commonly associated with its use. 1 The vancomycin ther.

Enfortumab Vedotin Showcases Impressive Safety, Efficacy in Cisplatin-Ineligible Urothelial Cancer

Feb 13th, 2021 - Enfortumab vedotin (Padcev) elicited the highest response rates observed for any regimen examined in cisplatin-ineligible patients with locally advanced or metastatic urothelial cancer who received prior PD-1/PD-L1 inhibitors, according to data fr...

Hospira, Inc. Issues a Voluntary Nationwide Recall of 8.4% Sodium Bicarbonate Injection, USP Due to the Presence of Particulate Matter | FDA

Summary Company Announcement Date: March 15, 2019 FDA Publish Date: March 15, 2019 Product Type: Drugs Generic Drugs Reason for Announcement: Recall Reason Description Presence of Particulate Matter Company Name: Hospira, Inc. Brand Name: Brand Na...

Optimal Sedation Strategies for COVID-19 ICU Patients

Oct 9th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. According to the best available evidence, analagosedation remains the focus for managing COVID-19 ICU patients, according to Steven B. Greenberg, ...

Solutions for Diabetic Ketoacidosis: Finding the Right Balance

Oct 2nd, 2020 - Recent studies have shown improved renal outcomes in adult patients with sepsis receiving balanced solutions instead of "normal" saline. For years, it has been known that 0.9% saline (colloquially referred to as "abnormal saline") can cause a hype...

see more →