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About 455 results

ALLMedicine™ Necrobiosis Lipoidica Center

Research & Reviews  99 results

A Clinical Trial to Evaluate PCS499 in Treating Ulcerations in Patients Who Have Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT04800562

Aug 3rd, 2022 - This is a randomized, double blind, placebo controlled study that will evaluate the efficacy and safety of PCS499 as compared to placebo for the treatment of ulcerations of patients with necrobiosis lipoidica (NL) and will inform the design of fut...

Understanding the zebras of wound care: an overview of atypical wounds.
https://www.ncbi.nlm.nih.gov/pubmed/35839157
Wounds : a Compendium of Clinical Research and Practice; Ansert E, Tickner A et. al.

Jul 16th, 2022 - Atypical wounds account for approximately 5% to 20% of chronic ulcerations. Typically, clinical suspicion of an uncommon etiology is warranted for wounds that do not show signs of healing with conventional care, that are associated with pain out o...

Ulcerated lower leg lesion
https://www.mdedge.com/familymedicine/article/255134/dermatology/ulcerated-lower-leg-lesion
MDedge Family Medicine;

Jun 2nd, 2022 - The patient’s atrophic plaques with a violaceous rim, indurated borders, and ulceration on the anterior pretibial surface were consistent with ulcerated necrobiosis lipoidica (NL). NL typically manifests on the bilateral pretibial region as small.

Granuloma annulare and necrobiosis lipoidica in a patient with HNF1A-MODY.
https://doi.org/10.20945/2359-3997000000477
Archives of Endocrinology and Metabolism; Brandes GIG, Peixoto-Barbosa R et. al.

May 14th, 2022 - Maturity-onset diabetes of the young (MODY) is a heterogeneous group of monogenic forms of diabetes mellitus with distinct clinical features. Clinical dermatological phenotypes in MODY patients are very rare in literature. This report describes a ...

Histopathologic features of necrobiosis lipoidica.
https://doi.org/10.1111/cup.14238
Journal of Cutaneous Pathology; Johnson E, Patel MH et. al.

Apr 12th, 2022 - Necrobiosis lipoidica (NL) is an uncommon granulomatous dermatosis that can occur in patients with or without associated diabetes mellitus (DM). Prior studies have attempted to determine distinctive histopathologic features of NL in patients with ...

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Drugs  61 results see all →

Clinicaltrials.gov  4 results

A Clinical Trial to Evaluate PCS499 in Treating Ulcerations in Patients Who Have Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT04800562

Aug 3rd, 2022 - This is a randomized, double blind, placebo controlled study that will evaluate the efficacy and safety of PCS499 as compared to placebo for the treatment of ulcerations of patients with necrobiosis lipoidica (NL) and will inform the design of fut...

Ruxolitinib Cream in the Treatment of Cutaneous Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT04492618

Mar 21st, 2022 - This research study is evaluating the safety and efficacy of a topical drug treatment "Ruxolitinib" in treating Necrobiosis Lipoidica (NL).

Secukinumab for NLD (Cosentyx) in Patients With Necrobiosis Lipoidica Diabeticorum (NLD)
https://clinicaltrials.gov/ct2/show/NCT03791060

Feb 21st, 2022 - Necrobiosis lipoidica diabeticorum (NLD) is a rare granulomatous condition of the skin often presenting with papules and eventually atrophic plaques, most commonly on the distal extensor lower extremities, which can be painful and disfiguring. Cur...

A Study to Evaluate the Safety and Tolerability of PCS499 for the Treatment of Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT03698864

Mar 19th, 2020 - This is an open-label study that will evaluate the safety of PCS499 for the treatment of necrobiosis lipoidica (NL) and will inform the design of future studies. Approximately 12 NL patients (6-9 patients without ulceration and 3-6 patients with u...

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News  18 results

Ulcerated lower leg lesion
https://www.mdedge.com/familymedicine/article/255134/dermatology/ulcerated-lower-leg-lesion
MDedge Family Medicine;

Jun 2nd, 2022 - The patient’s atrophic plaques with a violaceous rim, indurated borders, and ulceration on the anterior pretibial surface were consistent with ulcerated necrobiosis lipoidica (NL). NL typically manifests on the bilateral pretibial region as small.

Yellow pruritic eruption
https://www.mdedge.com/familymedicine/article/247705/dermatology/yellow-pruritic-eruption
MDedge Family Medicine;

Oct 21st, 2021 - This pruritic, eruption with yellowing atrophy and telangiectasias on the lower extremities is a classic presentation for necrobiosis lipoidica (NL). NL is a chronic granulomatous disorder with a predilection for the lower extremities.

Leg rash
https://www.mdedge.com/familymedicine/article/243044/dermatology/leg-rash
MDedge Family Medicine;

Jul 29th, 2021 - The appearance and location of this rash are classic signs for necrobiosis lipoidica, a chronic granulomatous skin disease commonly associated with diabetes. The patient’s initial hemoglobin A1c was 12.

A woman with a history of diabetes, and plaques on both shins
https://www.mdedge.com/dermatology/article/238741/medical-dermatology/woman-history-diabetes-and-plaques-both-shins
Donna Bilu Martin, MD

Apr 15th, 2021 - Necrobiosis lipoidica, or Necrobiosis lipoidica diabeticorum (NLD), is an uncommon dermatologic condition that presents as plaques on the skin. Women are often more affected than men.

Multiple Nontender Subcutaneous Nodules on the Finger
https://www.mdedge.com/dermatology/article/233366/dermatopathology/multiple-nontender-subcutaneous-nodules-finger
Carlos J. Sarriera-Lázaro, MD, Beau DiCicco, MD et. al.

Dec 11th, 2020 - The Diagnosis: Subcutaneous Granuloma Annulare Subcutaneous granuloma annulare (SGA), also known as deep GA, is a rare variant of GA that usually occurs in children and young adults. It presents as single or multiple, nontender, deep dermal and/or.

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