ALLMedicine™ Necrobiosis Lipoidica Center
Research & Reviews 102 results
https://clinicaltrials.gov/ct2/show/NCT04800562
Feb 27th, 2023 - This is a randomized, double blind, placebo controlled study that will evaluate the efficacy and safety of PCS499 as compared to placebo for the treatment of ulcerations of patients with necrobiosis lipoidica (NL) and will inform the design of fut...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901077
World Journal of Surgical Oncology; Bota O, Meier F et. al.
Feb 8th, 2023 - Extensive loss of soft tissue and bone due to neoplasia, trauma, or infection in extremities often leads to amputation. We present the case of a 72-year-old female patient presenting with an extended cutaneous squamous cell carcinoma of the lower ...
https://clinicaltrials.gov/ct2/show/NCT04492618
Feb 8th, 2023 - This research study is evaluating the safety and efficacy of a topical drug treatment "Ruxolitinib" in treating Necrobiosis Lipoidica (NL).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811805
Journal of Medical Case Reports; Kelati A, Durupt F et. al.
Jan 4th, 2023 - Necrobiosis lipoidica located to the breast; without evidence of glucose intolerance, is extremely rare, and its association to Crohn's disease is not usual. We report an interesting case of an association of necrobiosis lipoidica of the breast an...
https://doi.org/10.1111/ijd.16529
International Journal of Dermatology; Hines A, Butterfield R et. al.
Dec 9th, 2022 - Necrobiosis lipoidica (NL) is complicated by ulceration in up to 35% of cases. Retrospective study of patients with NL seen at our institution between January 1, 1992, and May 25, 2021, was conducted. Ulcerated NL (UNL, n = 83) and non-ulcerated N...
Drugs 85 results see all →
Clinicaltrials.gov 4 results
https://clinicaltrials.gov/ct2/show/NCT04800562
Feb 27th, 2023 - This is a randomized, double blind, placebo controlled study that will evaluate the efficacy and safety of PCS499 as compared to placebo for the treatment of ulcerations of patients with necrobiosis lipoidica (NL) and will inform the design of fut...
https://clinicaltrials.gov/ct2/show/NCT04492618
Feb 8th, 2023 - This research study is evaluating the safety and efficacy of a topical drug treatment "Ruxolitinib" in treating Necrobiosis Lipoidica (NL).
https://clinicaltrials.gov/ct2/show/NCT03698864
Oct 3rd, 2022 - This is an open-label study that will evaluate the safety of PCS499 for the treatment of necrobiosis lipoidica (NL) and will inform the design of future studies. Approximately 12 NL patients (6-9 patients without ulceration and 3-6 patients with u...
https://clinicaltrials.gov/ct2/show/NCT03791060
Feb 21st, 2022 - Necrobiosis lipoidica diabeticorum (NLD) is a rare granulomatous condition of the skin often presenting with papules and eventually atrophic plaques, most commonly on the distal extensor lower extremities, which can be painful and disfiguring. Cur...
News 18 results
https://www.mdedge.com/familymedicine/article/255134/dermatology/ulcerated-lower-leg-lesion
MDedge Family Medicine;
Jun 2nd, 2022 - The patient’s atrophic plaques with a violaceous rim, indurated borders, and ulceration on the anterior pretibial surface were consistent with ulcerated necrobiosis lipoidica (NL). NL typically manifests on the bilateral pretibial region as small.
https://www.mdedge.com/familymedicine/article/247705/dermatology/yellow-pruritic-eruption
MDedge Family Medicine;
Oct 21st, 2021 - This pruritic, eruption with yellowing atrophy and telangiectasias on the lower extremities is a classic presentation for necrobiosis lipoidica (NL). NL is a chronic granulomatous disorder with a predilection for the lower extremities.
https://www.mdedge.com/familymedicine/article/243044/dermatology/leg-rash
MDedge Family Medicine;
Jul 29th, 2021 - The appearance and location of this rash are classic signs for necrobiosis lipoidica, a chronic granulomatous skin disease commonly associated with diabetes. The patient’s initial hemoglobin A1c was 12.
https://www.mdedge.com/dermatology/article/238741/medical-dermatology/woman-history-diabetes-and-plaques-both-shins
Donna Bilu Martin, MD
Apr 15th, 2021 - Necrobiosis lipoidica, or Necrobiosis lipoidica diabeticorum (NLD), is an uncommon dermatologic condition that presents as plaques on the skin. Women are often more affected than men.
https://www.mdedge.com/dermatology/article/233366/dermatopathology/multiple-nontender-subcutaneous-nodules-finger
Carlos J. Sarriera-Lázaro, MD, Beau DiCicco, MD et. al.
Dec 11th, 2020 - The Diagnosis: Subcutaneous Granuloma Annulare Subcutaneous granuloma annulare (SGA), also known as deep GA, is a rare variant of GA that usually occurs in children and young adults. It presents as single or multiple, nontender, deep dermal and/or.