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About 523 results

ALLMedicine™ Necrobiosis Lipoidica Center

Research & Reviews  102 results

A Clinical Trial to Evaluate PCS499 in Treating Ulcerations in Patients Who Have Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT04800562

Feb 27th, 2023 - This is a randomized, double blind, placebo controlled study that will evaluate the efficacy and safety of PCS499 as compared to placebo for the treatment of ulcerations of patients with necrobiosis lipoidica (NL) and will inform the design of fut...

Lower leg reconstruction after resection of a squamous cell carcinoma on necrobiosis li...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901077
World Journal of Surgical Oncology; Bota O, Meier F et. al.

Feb 8th, 2023 - Extensive loss of soft tissue and bone due to neoplasia, trauma, or infection in extremities often leads to amputation. We present the case of a 72-year-old female patient presenting with an extended cutaneous squamous cell carcinoma of the lower ...

Ruxolitinib Cream in the Treatment of Cutaneous Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT04492618

Feb 8th, 2023 - This research study is evaluating the safety and efficacy of a topical drug treatment "Ruxolitinib" in treating Necrobiosis Lipoidica (NL).

Necrobiosis lipoidica of the breast associated with Crohn's disease: a case report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811805
Journal of Medical Case Reports; Kelati A, Durupt F et. al.

Jan 4th, 2023 - Necrobiosis lipoidica located to the breast; without evidence of glucose intolerance, is extremely rare, and its association to Crohn's disease is not usual. We report an interesting case of an association of necrobiosis lipoidica of the breast an...

Characteristics of ulcerated and non-ulcerated necrobiosis lipoidica.
https://doi.org/10.1111/ijd.16529
International Journal of Dermatology; Hines A, Butterfield R et. al.

Dec 9th, 2022 - Necrobiosis lipoidica (NL) is complicated by ulceration in up to 35% of cases. Retrospective study of patients with NL seen at our institution between January 1, 1992, and May 25, 2021, was conducted. Ulcerated NL (UNL, n = 83) and non-ulcerated N...

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Drugs  85 results see all →

Clinicaltrials.gov  4 results

A Clinical Trial to Evaluate PCS499 in Treating Ulcerations in Patients Who Have Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT04800562

Feb 27th, 2023 - This is a randomized, double blind, placebo controlled study that will evaluate the efficacy and safety of PCS499 as compared to placebo for the treatment of ulcerations of patients with necrobiosis lipoidica (NL) and will inform the design of fut...

Ruxolitinib Cream in the Treatment of Cutaneous Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT04492618

Feb 8th, 2023 - This research study is evaluating the safety and efficacy of a topical drug treatment "Ruxolitinib" in treating Necrobiosis Lipoidica (NL).

A Study to Evaluate the Safety and Tolerability of PCS499 for the Treatment of Necrobiosis Lipoidica
https://clinicaltrials.gov/ct2/show/NCT03698864

Oct 3rd, 2022 - This is an open-label study that will evaluate the safety of PCS499 for the treatment of necrobiosis lipoidica (NL) and will inform the design of future studies. Approximately 12 NL patients (6-9 patients without ulceration and 3-6 patients with u...

Secukinumab for NLD (Cosentyx) in Patients With Necrobiosis Lipoidica Diabeticorum (NLD)
https://clinicaltrials.gov/ct2/show/NCT03791060

Feb 21st, 2022 - Necrobiosis lipoidica diabeticorum (NLD) is a rare granulomatous condition of the skin often presenting with papules and eventually atrophic plaques, most commonly on the distal extensor lower extremities, which can be painful and disfiguring. Cur...

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News  18 results

Ulcerated lower leg lesion
https://www.mdedge.com/familymedicine/article/255134/dermatology/ulcerated-lower-leg-lesion
MDedge Family Medicine;

Jun 2nd, 2022 - The patient’s atrophic plaques with a violaceous rim, indurated borders, and ulceration on the anterior pretibial surface were consistent with ulcerated necrobiosis lipoidica (NL). NL typically manifests on the bilateral pretibial region as small.

Yellow pruritic eruption
https://www.mdedge.com/familymedicine/article/247705/dermatology/yellow-pruritic-eruption
MDedge Family Medicine;

Oct 21st, 2021 - This pruritic, eruption with yellowing atrophy and telangiectasias on the lower extremities is a classic presentation for necrobiosis lipoidica (NL). NL is a chronic granulomatous disorder with a predilection for the lower extremities.

Leg rash
https://www.mdedge.com/familymedicine/article/243044/dermatology/leg-rash
MDedge Family Medicine;

Jul 29th, 2021 - The appearance and location of this rash are classic signs for necrobiosis lipoidica, a chronic granulomatous skin disease commonly associated with diabetes. The patient’s initial hemoglobin A1c was 12.

A woman with a history of diabetes, and plaques on both shins
https://www.mdedge.com/dermatology/article/238741/medical-dermatology/woman-history-diabetes-and-plaques-both-shins
Donna Bilu Martin, MD

Apr 15th, 2021 - Necrobiosis lipoidica, or Necrobiosis lipoidica diabeticorum (NLD), is an uncommon dermatologic condition that presents as plaques on the skin. Women are often more affected than men.

Multiple Nontender Subcutaneous Nodules on the Finger
https://www.mdedge.com/dermatology/article/233366/dermatopathology/multiple-nontender-subcutaneous-nodules-finger
Carlos J. Sarriera-Lázaro, MD, Beau DiCicco, MD et. al.

Dec 11th, 2020 - The Diagnosis: Subcutaneous Granuloma Annulare Subcutaneous granuloma annulare (SGA), also known as deep GA, is a rare variant of GA that usually occurs in children and young adults. It presents as single or multiple, nontender, deep dermal and/or.

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