ALLMedicine™ Hypoparathyroidism Center

Mar 17th, 2023 - Thyroid surgery remains an essential treatment of thyroid cancer. The historical one-size-fits-all approach to differentiated (papillary and follicular) thyroid carcinoma of total thyroidectomy with central lymph node dissection has been shown to ...

Mar 16th, 2023 - Bone is one of the main targets of hormones and endocrine diseases are frequent causes of secondary osteoporosis and fractures in real-world clinical practice. However, diagnosis of skeletal fragility and prediction of fractures in this setting co...

Mar 16th, 2023 - Kenny-Caffey syndrome (KCS) is a rare hereditary disorder characterized by short stature, hypoparathyroidism and electrolyte disturbances. KCS1 and KCS2 are caused by pathogenic variants in TBCE and FAM111A, respectively. Clinically the phenotypes...

Mar 14th, 2023 - To investigate surgical, and clinical outcomes in patients with low-risk papillary thyroid microcarcinoma (PTMC) according to treatment options (immediate operation [IOP] vs. delayed operation following active surveillance (AS) [DOP]). AS has been...

Mar 10th, 2023 - Study Description: This will be a single-site, proof-of-principle, open-label study t-explore the PTH-independent effects of encaleret on calcium homeostasis in patients with low or undetectable PTH levels as a result of neck surgery (PSH). Object...

Nov 17th, 2022 - The 2022 International Task Force guidelines for chronic hypoparathyroidism will be published within several months in the Journal of Bone and Mineral Research. These guidelines update the original guidelines published in 2016, and include new inf...

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

Jun 1st, 2018 - Hypoparathyroidism (hypoPT) is the most common complication following bilateral thyroid operations. Thyroid surgeons must employ strategies for minimizing and preventing post-thyroidectomy hypoPT. The objective of this American Thyroid Association...

Apr 26th, 2018 - Objective To present an update on the diagnosis and treatment of hypoparathyroidism based on the most recent scientific evidence. Materials and methods The Department of Bone and Mineral Metabolism of the Sociedade Brasileira de Endocrinologia e M...

Jul 15th, 2015 - Hypoparathyroidism (HypoPT) is a rare (orphan) endocrine disease with low calcium and inappropriately low (insufficient) circulating parathyroid hormone levels, most often in adults secondary to thyroid surgery. Standard treatment is activated vit...

Mar 10th, 2023 - Study Description: This will be a single-site, proof-of-principle, open-label study t-explore the PTH-independent effects of encaleret on calcium homeostasis in patients with low or undetectable PTH levels as a result of neck surgery (PSH). Object...

Mar 8th, 2023 - Population of study & disease condition The study will include 88 infants and children with nutritional rickets Study setting: The patients will be recruited from out-patient clinic of Cairo University Children's Hospital. - Inclusion criteria: An...

Mar 7th, 2023 - The incidence of temporary hypoparathyroidism after thyroid surgery is 14%-60%, and the incidence of permanent hypoparathyroidism is 4%-11%. The protection of parathyroids has always been the focus and difficulty of thyroid surgery. The anatomical...

Mar 6th, 2023 - The main aim of this study is to find out the long-term safety and effectiveness profile of recombinant human parathyroid hormone (1-84) (rhPTH[1-84]) treatment in participants with chronic hypoparathyroidism under conditions of routine clinical p...

Feb 27th, 2023 - This is an expanded access program for eligible participants who previously received PTH treatment and who are ineligible for an ongoing TransCon PTH clinical trial. The treating physician/investigator contacts Ascendis Pharma when, based on their...

Nov 3rd, 2022 - The study covered in this summary was published on Research Square as a preprint has not yet been peer reviewed. Key Takeaway Among women with hypoparathyroidism, bone mineral density (BMD) was increased, and there was no increase in fracture risk...

Nov 3rd, 2022 - The study covered in this summary was published in Research Square as a preprint and has not yet been peer reviewed. Key Takeaways For selected patients requiring total thyroidectomy, the transoral endoscopic thyroidectomy via vestibular approach ...

Nov 1st, 2022 - The FDA announced a voluntary recall of one lot of Mylan's octreotide acetate injection due to possible glass particles in the syringes. Could the nationwide semaglutide (Wegovy, Ozempic) shortage be due to its growing popularity across social med...

Aug 10th, 2022 - The study covered in this summary was published on Research Square as a preprint and has not yet been peer reviewed. Key Takeaways In a single-center, case-control study, 134 patients who underwent total thyroidectomy (TT) were compared with patie...

Jul 6th, 2022 - After being hit with a clinical hold, Vertex Pharmaceuticals announced it's been given the FDA green-light to push forward on its phase I/II trial for the investigative type 1 diabetes stem cell treatment VX-880. According to a 4-year study, kids ...