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About 2,508 results

ALLMedicine™ Hypoparathyroidism Center

Research & Reviews  810 results

Novel Glial Cells Missing-2 (GCM2) Variants in Parathyroid Disorders.
https://doi.org/10.1530/EJE-21-0433
European Journal of Endocrinology; Canaff L, Guarnieri V et. al.

Jan 18th, 2022 - Our aim was to analyze variants of the gene glial cells missing-2 (GCM2), encoding a parathyroid cell-specific transcription factor, in familial hypoparathyroidism, and in Familial Isolated Hyperparathyroidism (FIHP) without and with a parathyroid...

Molecular and clinical characterization of autoimmune polyendocrinopathy-candidiasis-ec...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734050
Orphanet Journal of Rare Diseases; Setoodeh A, Panjeh-Shahi S et. al.

Jan 8th, 2022 - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome (APECED) is a rare autosomal recessive systemic autoimmune disease caused by mutations in the autoimmune regulator (AIRE) gene. Incidence of this genetic disorder is estimated...

Teriparatide administration by the Omnipod pump: preliminary experience from two cases ...
https://doi.org/10.1007/s12020-021-02978-6
Endocrine Aouchiche K, Reynaud R et. al.

Jan 6th, 2022 - Hypoparathyroidism (hypoPTH) in adults is mainly due to total thyroidectomy. Conventional therapies (calcium, active vitamin D) can fail to normalize calcemia, expose the patient to hypercalciuria and impact quality-of-life. Human parathormone (PT...

Outcomes of Early Versus Delayed Completion Thyroidectomy for Malignancy.
https://doi.org/10.1177/00031348211067999
The American Surgeon; Park JJ, Frank E et. al.

Jan 4th, 2022 - To determine whether time interval between hemi-thyroidectomy and subsequent completion thyroidectomy impacts outcomes. Retrospective review of 68 patients having completion thyroidectomy from August 2012 to December 2019. Patients were separated ...

Thyroidectomy with and without laryngectomy: Differences in post-operative hypocalcemia...
https://doi.org/10.1016/j.amjoto.2021.103316
American Journal of Otolaryngology; Phalke NP, Meyers FR et. al.

Dec 25th, 2021 - Total laryngectomy (TL) with thyroidectomy can pose significant risks to parathyroid function, and variance in rates of post-operative hypocalcemia (POH) based on extent of thyroidectomy have not been previously reported. Our objective is to ident...

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Guidelines  5 results

Management of immune-related adverse events in endocrine organs induced by immune check...
https://doi.org/10.1507/endocrj.EJ19-0163
Endocrine Journal; Arima H, Iwama S et. al.

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, ...
https://doi.org/10.1089/thy.2017.0309
Thyroid : Official Journal of the American Thyroid Associ... Orloff LA, Wiseman SM et. al.

Jun 1st, 2018 - Hypoparathyroidism (hypoPT) is the most common complication following bilateral thyroid operations. Thyroid surgeons must employ strategies for minimizing and preventing post-thyroidectomy hypoPT. The objective of this American Thyroid Association...

Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian ...
https://doi.org/10.20945/2359-3997000000015
Archives of Endocrinology and Metabolism; Maeda SS, Moreira CA et. al.

Apr 26th, 2018 - Objective To present an update on the diagnosis and treatment of hypoparathyroidism based on the most recent scientific evidence. Materials and methods The Department of Bone and Mineral Metabolism of the Sociedade Brasileira de Endocrinologia e M...

European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyr...
https://doi.org/10.1530/EJE-15-0628
European Journal of Endocrinology; Bollerslev J, Rejnmark L et. al.

Jul 15th, 2015 - Hypoparathyroidism (HypoPT) is a rare (orphan) endocrine disease with low calcium and inappropriately low (insufficient) circulating parathyroid hormone levels, most often in adults secondary to thyroid surgery. Standard treatment is activated vit...

American Thyroid Association statement on optimal surgical management of goiter.
https://doi.org/10.1089/thy.2013.0291
Thyroid : Official Journal of the American Thyroid Associ... Chen AY, Bernet VJ et. al.

Dec 4th, 2013 - Goiter, or benign enlargement of the thyroid gland, can be asymptomatic or can cause compression of surrounding structures such as the esophagus and/or trachea. The options for medical treatment of euthyroid goiter are short-lived and are limited ...

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Drugs  68 results see all →

Clinicaltrials.gov  36 results

QoL and Cognitive Function in Patients With Hypoparathyroidism
https://clinicaltrials.gov/ct2/show/NCT04569604

Dec 23rd, 2021 - Hypoparathyroidism (HypoPT) is a disease with inadequate production of parathyroid hormone (PTH) from the parathyroid glands leading to hypocalcemia. The most common form is postsurgical HypoPT due to neck surgery resulting in removed or damaged p...

Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism
https://clinicaltrials.gov/ct2/show/NCT05114980

Nov 10th, 2021 - Hypoparathyroidism (HypoPT) is a clinical condition characterized by hypocalcemia and low parathyroid hormone levels (PTH). HypoPT is most often the result from previous neck surgery such as thyroidectomy, parathyroidectomy and cervical dissection...

Study of the Feasibility of Radiofrequency Ablation of Benign Thyroid Nodules
https://clinicaltrials.gov/ct2/show/NCT03646383

Oct 28th, 2021 - Thyroid benign nodules represent a major public health problem because they are very common (subclinical nodules were found in half of woman beyond 60 years). The main risk factors include age, female gender, parity, smoking and family history of ...

Near Infrared (NIR) Autofluorescence Image-guided Thyroid Surgery
https://clinicaltrials.gov/ct2/show/NCT04193332

Sep 22nd, 2021 - Patients admitted to total thyroidectomy or completion thyroidectomy is ramdomized to: Intervention: NIR optic imaging assisted identification of the parathyroid glands during thyroidectomy using parathyroid gland autofluorescence. Control: Conven...

Does Parathyroid Autofluorescence Reduces Unintensional Parathyroidectomy During Total Thyroidectomy With Central Lymph Node Compartment Dissection
https://clinicaltrials.gov/ct2/show/NCT04339478

Aug 26th, 2021 - Real-time intraoperative identification and functional maintenance of structures are of major importance in endocrine surgery, with a critical role in clinical outcomes and patients' quality of life. Despite the advances in preoperative imaging te...

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News  82 results

Hypoparathyroidism Rates Low After Thyroidectomy for Graves Disease
https://www.medscape.com/viewarticle/960909

Oct 14th, 2021 - Dr Carolyn Seib Older people treated for Graves disease with total thyroidectomy in the United States are at low risk of developing hypoparathyroidism, according to results from a large population-based cohort study. "The risk of permanent hypopar...

Denosumab: A Review of Its Pharmacology and Clinical Implications
https://www.onclive.com/view/denosumab-a-review-of-its-pharmacology-and-clinical-implications

Oct 4th, 2021 - Background Osteoporosis is characterized by low bone mass, deterioration of bone tissue and architecture, compromised bone strength, and an increase in fracture risk.1 The World Health Organization (WHO) defines osteoporosis as a bone mineral de...

COVID Risk in T1D; Lilly to Drop Some Insulin Prices; New ADA/EASD T1D Guideline
https://www.medpagetoday.com/endocrinology/generalendocrinology/94815

Oct 3rd, 2021 - Adults over age 40 with type 1 diabetes (T1D) faced more severe COVID-19 outcomes, including a higher risk of hospitalization and death, compared with children and young adults with the condition. "These findings indicate the need for age-tailored...

New Form of Parathyroid Hormone Cuts Need for Conventional Therapy in Chronic Hypoparathyroidism
https://www.medscape.com/viewarticle/958613

Sep 15th, 2021 - NEW YORK (Reuters Health) - In adults with chronic hypoparathyroidism, an investigational prodrug of parathyroid hormone, TransCon PTH, allowed most participants in a small randomized trial to reduce or forgo conventional therapy of vitamin D and ...

Tubeless Insulin Pump Works; Insulin Pens vs Syringes; Caffeine and Osteoporosis
https://www.medpagetoday.com/endocrinology/generalendocrinology/93736

Jul 25th, 2021 - A tubeless, patch-pump automated insulin-delivery system -- Insulet's Omnipod 5 -- was both safe and effective in a prospective study of kids and adults with type 1 diabetes. Following a positive meeting with the FDA, Radius Health announced plans...

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Patient Education  2 results see all →