About 708 results

ALLMedicine™ Parathyroid Carcinoma Center

Research & Reviews  234 results

Molecular and Clinical Spectrum of Primary Hyperparathyroidism.
Endocrine Reviews; Jha S, Simonds WF

Mar 25th, 2023 - Recent data suggest an increase in the overall incidence of parathyroid disorders with primary hyperparathyroidism (PHPT) being the most prevalent parathyroid disorder. PHPT is associated with morbidities (fractures, kidney stones, chronic kidney ...

A Nomogram for Relapse/Death and Contemplating Adjuvant Therapy for Parathyroid Carcinoma.
Surgical Oncology Clinics of North America; Silva-Figueroa AM

Mar 17th, 2023 - Parathyroid carcinoma (PC) is a rare endocrine malignancy with an increased incidence in the last decade. There is no reliable prognostic staging system for PC. Several hosts, tumors, and tumor microenvironment factors have been negatively correla...

Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic...
Molecular Oncology; Teleanu MV, Fuss CT et. al.

Feb 23rd, 2023 - Parathyroid carcinoma (PC) is an ultra-rare malignancy with a high risk of recurrence after surgery. Tumor-directed systemic treatments for PC are not established. We used whole-genome and RNA sequencing in four patients with advanced PC to identi...

Evaluation of factors predicting postoperative recurrence and metastasis of parathyroid...
World Journal of Surgical Oncology; Ohkuwa K, Katoh R et. al.

Feb 5th, 2023 - The purpose of this study was to examine the postoperative clinical course of parathyroid carcinoma to determine factors that predict postoperative recurrence and distant metastasis. In this retrospective study, we included 38 patients with parath...

Clinicopathologic characteristics of thymic clear cell carcinoma: a case report with li...
Journal of Cardiothoracic Surgery; Zhao Z, Zeng Q et. al.

Feb 3rd, 2023 - Thymic clear cell carcinoma is a rare mediastinal neoplasm, with only 25 reported cases to date. We report a case of a 45-year-old man with thymic clear cell carcinoma. We think imaging and laboratory tests may be helpful for differential diagnosi...

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Guidelines  1 results

2009 EANM parathyroid guidelines.
European Journal of Nuclear Medicine and Molecular Imaging; Hindié E, Ugur O et. al.

May 28th, 2009 - The present guidelines were issued by the Parathyroid Task Group of the European Association of Nuclear Medicine. The main focus was imaging of primary hyperparathyroidism. Dual-tracer and single-tracer parathyroid scintigraphy protocols were disc...

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Drugs  34 results see all →

Clinicaltrials.gov  8 results

VATS for Resection of Mediastinal Parathyroids

Jan 25th, 2023 - Hyperparathyroidism (HPT) is a clinical disorder characterized by an inappropriately elevated paratohormone (PTH) due to hypersecretion of one or more parathyroid glands, that may develop secondary hypercalcemia and other metabolic disturbances. T...

F-18 PSMA for Localization of Parathyroid Adenoma

Apr 4th, 2022 - Hyperparathyroidism is an increasingly significant medical and public health condition in the United States. In the past two decades, the incidence of hyperparathyroidism has increased 300%, and currently, the disease affects at least 30,000 new p...

Phase 3 Study of KHK7580 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Primary Hyperparathyroidism

May 27th, 2021 - To evaluate the efficacy of KHK7580 orally administered up to 24 weeks for hypercalcemia in patient with parathyroid carcinoma or primary hyperparathyroidism who are unable to undergo parathyroidectomy or relapse after parathyroidectomy.

Effect of Cinacalcet on Parathyroid Hormone Secretion in Children and Adolescents With Hypophosphatemic Rickets

Jan 19th, 2021 - X-linked hypophosphatemic rickets (XLH) is an X-linked dominant genetic disorder. Common findings are low serum phosphate and inadequate 1,25(OH)2 vitamin D production. It is generally believed that the primary defect in XLH is impaired renal tubu...

Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers

Sep 7th, 2020 - PRIMARY OBJECTIVE: I. Objective response rate (ORR) by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 determined by Ia. Computed tomography (CT) or Ib. Magnetic resonance imaging (MRI). SECONDARY OBJECTIVES: I. To estimate progression-f...

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News  6 results

A 38-Year-Old Man With Back and Side Pain: Osmosis USMLE Study Question

Feb 21st, 2020 - Nephrocalcinosis is a condition characterized by the calcification of the renal tubules that leads to renal insufficiency. This occurs via metastatic calcification, which means that calcium is deposited in normal tissues, rather than those that ha...

Primary hyperparathyroidism: Labs to order, Tx to consider
MDedge Family Medicine; Padmaja Sanapureddy, MD, Vishnu Vardhan Garla, MD et. al.

Nov 1st, 2018 - Since the advent of multichannel serum chemistry screening in the 1970s, large numbers of asymptomatic cases of primary hyperparathyroidism (PHPT) have been discovered. The clinical spectrum of the disease has changed from the classic “moans, groa.

Death Halts Sensipar Trials in Kids

Feb 26th, 2013 - The FDA today suspended all pediatric clinical trials of cinacalcet hydrochloride (Sensipar) -- Amgen's calcium-sensing receptor agonist -- because of the death of a 14-year-old patient in one of the studies. The agency has not concluded that ther...

Cinacalcet Trials Halted Due to Pediatric Death

Feb 26th, 2013 - The US Food and Drug Administration (FDA) today announced that it has halted all pediatric clinical trials of cinacalcet (Sensipar, Amgen), a calcium-lowering drug, after the recent death of a 14-year-old patient in a study. The FDA decision to st...

A 45-Year-Old Man With a Maxillary Mass and Hypercalcemia

Feb 28th, 2005 - Discussion The case of this unfortunate patient presents several points of interest. Brown tumors are rare, seen in fewer than 5% of patients with primary hyperparathyroidism today. Early detection of hypercalcemia due to rapid multichannel bioche...

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