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About 2,200 results

ALLMedicine™ Growth Hormone Deficiency Center

Research & Reviews  727 results

Growth response to growth hormone (GH) treatment in children with GH deficiency (GHD) a...
https://doi.org/10.1515/jpem-2021-0389
Journal of Pediatric Endocrinology & Metabolism : JPEM; Soliman A, Rogol AD et. al.

Jul 23rd, 2021 - Some idiopathic short stature (ISS) patients may have varying degrees of insulin-like growth factor 1 (IGFI) deficiency. Others with growth hormone deficiency (GHD) (peak GH < 7 ng/dL after provocation) have normal IGFI levels. Do children with IS...

Factors affecting IGF-I level and correlation with growth response during growth hormon...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289015
PloS One; Kim JH, Kim SJ et. al.

Jul 20th, 2021 - Growth hormone treatment strategies to achieve the goal include the titration of GH doses according to serum insulin-like growth factor I (IGF-I) concentrations. However, IGF-I levels do not always correlate well with the growth response. This stu...

Weekly Lonapegsomatropin in Treatment-Naïve Children with Growth Hormone Deficiency: Th...
https://doi.org/10.1210/clinem/dgab529
The Journal of Clinical Endocrinology and Metabolism; Thornton PS, Maniatis AK et. al.

Jul 18th, 2021 - For children with growth hormone deficiency (GHD), treatment burden with daily somatropin injections (hGH) is high, which may lead to poor adherence and suboptimal overall treatment outcomes. Lonapegsomatropin (TransCon hGH) is an investigational ...

A Systematic Review and Meta-Analysis of Stature Growth Complications in β-thalassemia ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194969
Annals of Global Health; Arab-Zozani E, Kheyrandish S et. al.

Jun 25th, 2021 - Blood transfusion is a traditional treatment for β-thalassemia (β-thal) that improves the patients' anemia and lifespan, but it may lead to iron overload in parenchymal tissue organs and endocrine glands that cause their dysfunctions as the iron r...

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Guidelines  1 results

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for Pr...
https://doi.org/10.1227/NEU.0000000000001387
Neurosurgery Fleseriu M, Bodach ME et. al.

Sep 17th, 2016 - Nonfunctioning pituitary adenomas (NFPAs) are among the most common pituitary lesions and may present with hypopituitarism and/or hyperprolactinemia. To review the existing literature as it pertains to preoperative endocrine assessment in the work...

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Drugs  14 results see all →

Clinicaltrials.gov  81 results

Dose Finding Study of GX-H9 in Paeditaric Patients With Growth Hormone Deficiency
https://clinicaltrials.gov/ct2/show/NCT03309891

Apr 20th, 2020 - GX-H9 is a new hGH product fused to hybrid Fc in studies as a once-a-week and every other week dosing regimen designed to overcome the inconvenience of daily rhGH injections and is under the studies designed to determine if the safety profile is c...

A Safety, Tolerability and Efficacy Study of TransCon hGH in Children With Growth Hormone Deficiency
https://clinicaltrials.gov/ct2/show/NCT03305016

Feb 25th, 2020 - A 26 week trial of TransCon hGH, a long-acting growth hormone product, administered once-a-week. Approximately 150 children (males and females) with growth hormone deficiency (GHD) will be included. All study participants will receive TransCon hGH...

A Long-Term Trial Investigating Safety and Efficacy of TransCon hGH in Children With Growth Hormone Deficiency Who Have Completed a Prior TransCon hGH Clinical Trial
https://clinicaltrials.gov/ct2/show/NCT03344458

Jan 22nd, 2020 - A multicenter, phase 3, long-term extension trial of TransCon hGH administered once-weekly in children with growth hormone deficiency (GHD) who previously participated in a phase 3 TransCon hGH trial. Approximately 300 children (males and females)...

A Post Marketing Surveillance Study for NutropinAq® in Adults With Growth Hormone Deficiency
https://clinicaltrials.gov/ct2/show/NCT00455884

Jan 14th, 2019 - This study is a multicenter, open-label, observational, post marketing surveillance program to collect information on the use of NutropinAq® in adults suffering from Growth Hormone Deficiency in Germany, Italy, and United Kingdom

Study to Assess Long-term Effectiveness of Zomacton® and Treatment Adherence in Patients With Growth Hormone Deficiency or Ullrich-Turner Syndrome
https://clinicaltrials.gov/ct2/show/NCT03274973

Dec 13th, 2018 - Assessment of long-term effectiveness of ZOMACTON in treatment of Growth Hormone Deficiency or growth retardation due to Ullrich-Turner Syndrome and assessment of compliance and adherence, optionally with the aid of an electronic app or patient di...

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News  55 results

Weight Gain Common in Childhood Brain Tumor Survivors
https://www.medscape.com/viewarticle/947349

Mar 12th, 2021 - Children who have been treated for brain tumors often experience significant weight gain, and new findings suggest that this could be a sign of hypothalamic-pituitary (HP) dysfunction. "We believe that endocrine surveillance should be initiated ea...

FDA OKs Somapacitan (Sogroya), First Once-Weekly Growth Hormone
https://www.medscape.com/viewarticle/936834

Sep 3rd, 2020 - The US Food and Drug Administration (FDA) has approved somapacitan (Sogroya, Novo Nordisk) for the replacement of endogenous growth hormone in adults with growth hormone deficiency (GHD).  Somapacitan is a human growth hormone analog. It is admini...

FDA OKs Somapacitan (Sogroya), First Once-Weekly Growth Hormone
https://www.staging.medscape.com/viewarticle/936834

Sep 3rd, 2020 - The US Food and Drug Administration (FDA) has approved somapacitan (Sogroya, Novo Nordisk) for the replacement of endogenous growth hormone in adults with growth hormone deficiency (GHD).  Somapacitan is a human growth hormone analog. It is admini...

Growth Hormone Deficiency Clinical Practice Guidelines (AACE/ACE, 2019)
https://reference.staging.medscape.com/viewarticle/924401

Jan 31st, 2020 - Guidelines for the management of growth hormone deficiency in adults and patients transitioning from pediatric to adult care were published in 2019 by the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinolo...

Growth Hormone Deficiency Clinical Practice Guidelines (AACE/ACE, 2019)
https://reference.medscape.com/viewarticle/924401

Jan 31st, 2020 - Guidelines for the management of growth hormone deficiency in adults and patients transitioning from pediatric to adult care were published in 2019 by the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinolo...

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Patient Education  2 results see all →