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About 3,111 results

ALLMedicine Hypopituitarism Center

Research & Reviews  1,495 results

Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors.
https://doi.org/10.1172/JCI136745
The Journal of Clinical Investigation; Brinkmeier ML, Bando H et. al.

May 26th, 2020 - The transcription factor ISL1 is expressed in pituitary gland stem cells and the thyrotrope and gonadotrope lineages. Pituitary-specific Isl1 deletion causes hypopituitarism with increased stem cell apoptosis, reduced differentiation of thyrotrope...

Predicting development of ipilimumab-induced hypophysitis: utility of T4 and TSH index ...
https://doi.org/10.1007/s40618-020-01297-3
Journal of Endocrinological Investigation; Siddiqui MS, Lai ZM et. al.

May 23rd, 2020 - Ipilimumab, a monoclonal antibody inhibiting CLTA-4, is an established treatment in metastatic melanoma, either alone or in combination with nivolumab, and results in immune mediated adverse events, including endocrinopathy. Hypophysitis is one of...

Motivation for and adherence to growth hormone replacement therapy in adults with hypop...
https://doi.org/10.1007/s11102-020-01046-y
Pituitary Kreitschmann-Andermahr I, Siegel S et. al.

May 20th, 2020 - While reasons for non-adherence in children requiring growth hormone (GH) replacement (GH-Rx) are well researched, few studies have investigated adherence in adult GH deficient patients. Against the background of the adverse medical sequelae of un...

Metabolic syndrome and its components in adult hypopituitary patients.
https://doi.org/10.1007/s11102-020-01048-w
Pituitary Abe SY, Dos Santos KS et. al.

May 17th, 2020 - To evaluate the prevalence of metabolic syndrome (MetS) and its components in adult hypopituitary patients. Retrospective, cross-sectional analysis of a cohort of hypopituitary adult patients followed in a single reference center for pituitary dis...

Hypopituitarism in five PROP1 mutation siblings: long-lasting natural course and the ef...
https://doi.org/10.1007/s11102-020-01049-9
Pituitary Doknic M, Gasic V et. al.

May 14th, 2020 - Twenty years after the first description of combined hypopituitarism (CPHD) caused by PROP1 mutations, the phenotype of affected subjects is still challenging for clinicians. These patients suffer from pituitary hormone deficits ranging from IGHD ...

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Guidelines  7 results

Management of immune-related adverse events in endocrine organs induced by immune check...
https://doi.org/10.1507/endocrj.EJ19-0163
Endocrine Journal; Arima H, Iwama S et. al.

Jun 27th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practi...
https://doi.org/10.1210/jc.2016-2118
The Journal of Clinical Endocrinology and Metabolism; Fleseriu M, Hashim IA et. al.

Nov 4th, 2016 - To formulate clinical practice guidelines for hormonal replacement in hypopituitarism in adults. The participants include an Endocrine Society-appointed Task Force of six experts, a methodologist, and a medical writer. The American Association for...

Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Gu...
https://academic.oup.com/jcem/article/101/11/3888/2764912
Fleseriu, M.

Oct 31st, 2016 - To formulate clinical practice guidelines for hormonal replacement in hypopituitarism in adults. The participants include an Endocrine Society-appointed Task Force of six experts, a methodologist, and a medical writer.

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for Pr...
https://doi.org/10.1227/NEU.0000000000001387
Neurosurgery Fleseriu M, Bodach ME et. al.

Sep 16th, 2016 - Nonfunctioning pituitary adenomas (NFPAs) are among the most common pituitary lesions and may present with hypopituitarism and/or hyperprolactinemia. To review the existing literature as it pertains to preoperative endocrine assessment in the work...

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Pri...
https://doi.org/10.1227/NEU.0000000000001389
Neurosurgery Lucas JW, Bodach ME et. al.

Sep 16th, 2016 - Nonfunctioning pituitary adenomas (NFPAs) are among the most common pituitary lesions and may present clinically with vision loss and hypopituitarism. To characterize the existing literature as it pertains to the initial management of NFPAs. A sys...

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Clinicaltrials.gov  1,553 results

Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors.
https://doi.org/10.1172/JCI136745
The Journal of Clinical Investigation; Brinkmeier ML, Bando H et. al.

May 26th, 2020 - The transcription factor ISL1 is expressed in pituitary gland stem cells and the thyrotrope and gonadotrope lineages. Pituitary-specific Isl1 deletion causes hypopituitarism with increased stem cell apoptosis, reduced differentiation of thyrotrope...

Predicting development of ipilimumab-induced hypophysitis: utility of T4 and TSH index ...
https://doi.org/10.1007/s40618-020-01297-3
Journal of Endocrinological Investigation; Siddiqui MS, Lai ZM et. al.

May 23rd, 2020 - Ipilimumab, a monoclonal antibody inhibiting CLTA-4, is an established treatment in metastatic melanoma, either alone or in combination with nivolumab, and results in immune mediated adverse events, including endocrinopathy. Hypophysitis is one of...

Motivation for and adherence to growth hormone replacement therapy in adults with hypop...
https://doi.org/10.1007/s11102-020-01046-y
Pituitary Kreitschmann-Andermahr I, Siegel S et. al.

May 20th, 2020 - While reasons for non-adherence in children requiring growth hormone (GH) replacement (GH-Rx) are well researched, few studies have investigated adherence in adult GH deficient patients. Against the background of the adverse medical sequelae of un...

Metabolic syndrome and its components in adult hypopituitary patients.
https://doi.org/10.1007/s11102-020-01048-w
Pituitary Abe SY, Dos Santos KS et. al.

May 17th, 2020 - To evaluate the prevalence of metabolic syndrome (MetS) and its components in adult hypopituitary patients. Retrospective, cross-sectional analysis of a cohort of hypopituitary adult patients followed in a single reference center for pituitary dis...

Hypopituitarism in five PROP1 mutation siblings: long-lasting natural course and the ef...
https://doi.org/10.1007/s11102-020-01049-9
Pituitary Doknic M, Gasic V et. al.

May 14th, 2020 - Twenty years after the first description of combined hypopituitarism (CPHD) caused by PROP1 mutations, the phenotype of affected subjects is still challenging for clinicians. These patients suffer from pituitary hormone deficits ranging from IGHD ...

see more →

News  45 results

Pituitary Hormones Should Be 'Restored to Healthy Levels'
https://www.medscape.com/viewarticle/870650

Oct 19th, 2016 - Patients with hypopituitarism should have their hormone levels restored as close to physiologic levels as possible, while taking into account potential interactions between hormones and other medications, say new guidelines on diagnosing and manag...

AACE: Endocrine treatment of childhood cancer survivors needs improvement
https://www.mdedge.com/internalmedicine/article/100131/pituitary-thyroid-adrenal-disorders/aace-endocrine-treatment
Deepak Chitnis

Jun 2nd, 2015 - NASHVILLE – Endocrinologists dealing with adult patients who survived cancer during childhood should ensure that they have an adequate understanding of the elevated risk that such patients are at for various endocrine conditions, such as hypogonad.

New guidelines address hypopituitarism in TBI
https://www.mdedge.com/neurology/article/99590/pituitary-thyroid-adrenal-disorders/new-guidelines-address-hypopituitarism
Jennie Smith

May 12th, 2015 - New guidelines on traumatic brain injury and neuroendocrine dysfunction ask clinicians to be mindful that hypopituitarism in TBI survivors can develop following injuries classified as mild and can be slow to develop. The guidelines – published onl.

Chronic Marijuana Use Linked to Hypopituitarism
https://www.medscape.com/viewarticle/803588

May 2nd, 2013 - PHOENIX — Chronic marijuana use was found to be the cause of hypopituitarism in a 37-year-old man, a case that highlights a potentially growing problem, say physicians. The case was reported in a poster and discussed in a press briefing here at th...

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Patient Education  11 results see all →