ALLMedicine™ Diabetes Insipidus Center

Sep 7th, 2021 - There is inconsistency in the amount of oral desmopressin (DDAVP) that children with central diabetes insipidus (CDI) require. We investigated whether clinical characteristics influenced DDAVP dose requirements in 100 children with CDI. Extremely ...

Aug 25th, 2021 - : Wolfram Syndrome is a rare genetic disorder usually inherited in an autosomal recessive manner. The acronym DIDMOAD characterizes the classic constellation of findings: diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. However,...

Aug 24th, 2021 - Modulating PD-1 expression can constrain tumor growth. Hodgkin lymphoma patients commonly express PD-L1 on tumor cells. We report the case of a 60-year-old male patient with relapsed classical Hodgkin lymphoma who suffered from immediate-onset chi...

Aug 19th, 2021 - Wolfram syndrome (WFS) is a rare autosomal recessive genetic disease whose main cause is mutations in the WFS1 and CISD2 genes. Its characteristic clinical manifestations are diabetes insipidus, diabetes mellitus, optic atrophy and deafness. In th...

Aug 5th, 2021 - Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare monogenic inherited disease caused by mutations of the autoimmune regulator gene (AIRE). The three major components of this syndrome are chronic mucocutaneous candidiasis, hypoparathyroidi...

Jul 23rd, 2021 - COVID-19 has changed the nature of medical consultations, emphasizing virtual patient counselling, with relevance for patients with diabetes insipidus (DI) or hyponatraemia. The main complication of desmopressin treatment in DI is dilutional hypon...

Feb 24th, 2011 - Wolfram syndrome, also referred to as DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy and deafness) is a genetic syndrome characterized by beta-cell dysfunction and apoptosis leading to diabetes, neurodegeneration and psychiatric ill...

Mar 12th, 2021 - Children who have been treated for brain tumors often experience significant weight gain, and new findings suggest that this could be a sign of hypothalamic-pituitary (HP) dysfunction. "We believe that endocrine surveillance should be initiated ea...

Mar 26th, 2020 - Answer 2/5 Which of the following signs and symptoms is most suggestive of pituitary metastasis in patients with a history of breast cancer? Your peers chose: Neurocognitive impairment with headache 0% Worsening of an existing seizure disorder and...

Aug 9th, 2018 - A blood test for copeptin, a precursor of antidiuretic hormone (ADH, vasopressin), differentiates between "harmless" polydipsia-polyuria and diabetes insipidus more quickly and accurately than a traditional water-deprivation test, researchers repo...

May 30th, 2018 - Diabetes insipidus is defined as the passage of large volumes of dilute urine. It has two major forms: central and nephrogenic. Central diabetes insipidus is characterized by decreased secretion of antidiuretic hormone (ADH), which gives rise to p...

May 30th, 2018 - The physical examination findings vary with the severity and chronicity of diabetes insipidus. The examination findings may be entirely normal. Hydronephrosis, with pelvic fullness, flank pain or tenderness, or pain radiating to the testicle or ge...