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About 3,010 results

ALLMedicine™ Growth Hormone Deficiency Center

Research & Reviews  947 results

Appropriate management of growth hormone deficiency during the age of transition: an It...
https://doi.org/10.1007/s40618-022-01880-w
Journal of Endocrinological Investigation; Cannavò S, Cappa M et. al.

Aug 13th, 2022 - Appropriate management of growth hormone deficiency during the age of transition: an Italian Delphi consensus statement.|2022|Cannavò S,Cappa M,Ferone D,Isidori AM,Loche S,|

A Phase 3, Multicenter Study To Evaluate The Efficacy And Safety Of MOD-4023 In Adults With Growth Hormone Deficiency
https://clinicaltrials.gov/ct2/show/NCT01909479

Aug 12th, 2022 - This will be a randomized, double-blind, placebo-controlled, parallel-group, multicenter study in adult subjects with GHD to assess the safety and efficacy of a long-acting, once weekly injection of modified hGH (MOD-4023).

Therapeutic delivery: industry update covering January 2022.
https://doi.org/10.4155/tde-2022-0032
Therapeutic Delivery; Simpson I

Aug 5th, 2022 - This industry update covers the period from January 1 through January 31, 2022, and is based on information sourced from company press releases, scientific literature, patents and news websites. January 2022 saw Janssen and Midatech expand their c...

Metabolic and QOL Effects of GH Treatment in Patients With TBI and AGHD
https://clinicaltrials.gov/ct2/show/NCT02988687

Aug 4th, 2022 - Growth hormone replacement has consistently shown improvements in body composition, exercise capacity, endothelial function, inflammatory biomarkers, bone mineral density, lipoprotein metabolism, and self-reported quality of Life (QOL) in patients...

Effect of Vitamin D Combined with Recombinant Human Growth Hormone in Children with Gro...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325485
Disease Markers; Wang P, Jin X et. al.

Jul 30th, 2022 - Growth hormone deficiency (GHD) refers to the complete or partial lack of pituitary growth hormone synthesis and secretion. This study is aimed at investigating the efficacy of vitamin D and recombinant human growth hormone (rhGH) in children with...

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Guidelines  1 results

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for Pr...
https://doi.org/10.1227/NEU.0000000000001387
Neurosurgery Fleseriu M, Bodach ME et. al.

Sep 17th, 2016 - Nonfunctioning pituitary adenomas (NFPAs) are among the most common pituitary lesions and may present with hypopituitarism and/or hyperprolactinemia. To review the existing literature as it pertains to preoperative endocrine assessment in the work...

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Drugs  14 results see all →

Clinicaltrials.gov  165 results

A Phase 3, Multicenter Study To Evaluate The Efficacy And Safety Of MOD-4023 In Adults With Growth Hormone Deficiency
https://clinicaltrials.gov/ct2/show/NCT01909479

Aug 12th, 2022 - This will be a randomized, double-blind, placebo-controlled, parallel-group, multicenter study in adult subjects with GHD to assess the safety and efficacy of a long-acting, once weekly injection of modified hGH (MOD-4023).

Metabolic and QOL Effects of GH Treatment in Patients With TBI and AGHD
https://clinicaltrials.gov/ct2/show/NCT02988687

Aug 4th, 2022 - Growth hormone replacement has consistently shown improvements in body composition, exercise capacity, endothelial function, inflammatory biomarkers, bone mineral density, lipoprotein metabolism, and self-reported quality of Life (QOL) in patients...

A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism
https://clinicaltrials.gov/ct2/show/NCT05187377

Jul 26th, 2022 - This study will show that select electrophysiological markers in PMS are relevant to iASD and predictive of treatment response with growth hormone. The long-term goal is to optimize treatment selection in iASD by establishing biological signature(...

Versartis Trial in Pre-pubertal Japanese Children With Growth Hormone Deficiency (GHD) to Assess Long-Acting Growth Hormone (Somavaratan, VRS-317)
https://clinicaltrials.gov/ct2/show/NCT02413138

Jul 25th, 2022 - The trial will consist of three stages: 1) a 30 day Phase 2 PK and PD evaluation of somavaratan, 2) an optional Phase 2 Extension and 3) a 12 month Phase 3 safety and efficacy stage. The study is a randomized, multi-center, open label study. The p...

Influence of Adherence to Growth Hormone Therapy (GHT) With Norditropin® on Near Final Height in Patients With Growth Hormone Deficiency (GHD) and Born Small for Gestational Age (SGA)
https://clinicaltrials.gov/ct2/show/NCT03972345

Jul 15th, 2022 - Participants are free to decide if they want to take part in this study or not. The study will be conducted to collect information about the influence of adherence to growth hormone therapy with Norditropin® in children and teenagers in daily prac...

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News  76 results

FDA Approves First Once-Weekly Growth Hormone for Children
https://www.medscape.com/viewarticle/958043

Sep 2nd, 2021 - The US Food and Drug Administration (FDA) has approved lonapegsomatropin (Skytrofa, Ascendis Pharma), the first weekly subcutaneous injectable growth hormone for children with growth hormone deficiency (GHD). The approval was based on the findings...

More Promising Tirzepatide Data; Continuous Glucose Monitoring Wins in Diabetes
https://www.medpagetoday.com/endocrinology/generalendocrinology/92929

Jun 6th, 2021 - The investigational dual GIP and GLP-1 receptor agonist tirzepatide significantly reduced HbA1c levels and induced weight loss in patients with type 2 diabetes compared with insulin glargine in the SURPASS-4 trial, Eli Lilly announced. A randomize...

Weight Gain Common in Childhood Brain Tumor Survivors
https://www.medscape.com/viewarticle/947349

Mar 12th, 2021 - Children who have been treated for brain tumors often experience significant weight gain, and new findings suggest that this could be a sign of hypothalamic-pituitary (HP) dysfunction. "We believe that endocrine surveillance should be initiated ea...

Childhood growth hormones raise risk for adult cardiovascular events
https://www.mdedge.com/pediatrics/article/234747/endocrinology/childhood-growth-hormones-raise-risk-adult-cardiovascular
Heidi Splete

Jan 19th, 2021 - Childhood treatment with recombinant human growth hormone was associated with a significantly increased risk of cardiovascular events, based on data from more than 3,000 individuals. “Both excess levels of growth hormone and [growth hormone defici.

First-of-Its Kind Guideline on Lipid Monitoring in Endocrine Diseases
https://www.staging.medscape.com/viewarticle/940135

Nov 2nd, 2020 - Endocrine diseases of any type — not just diabetes — can represent a cardiovascular risk and patients with those disorders should be screened for high cholesterol, according to a new clinical practice guideline from the Endocrine Society. "The sim...

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Patient Education  1 results see all →