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About 3,235 results

ALLMedicine Medullary Thyroid Carcinoma Center

Research & Reviews  1,577 results

Early thyroidectomy in multiple endocrine neoplasia: a four decade experience.
https://doi.org/10.1530/ERC-20-0108
Endocrine-related Cancer; Grubbs EG, Lechan RM et. al.

May 28th, 2020 - Forty years ago, physicians caring for the J-kindred, a 100+ member family with multiple endocrine neoplasia type 2A (MEN2A), hypothesized that early thyroidectomy based on measurement of the biomarker calcitonin could cure patients at risk for de...

First proof of association between autoimmune polyglandular syndrome and multiple endoc...
https://doi.org/10.1507/endocrj.EJ20-0099
Endocrine Journal; Manso J, Censi S et. al.

May 28th, 2020 - Autoimmune Addison's disease (AAD) is a rare condition occurring either in isolation or associated with other autoimmune diseases as part of an autoimmune polyglandular syndrome (APS) type 1, 2 or 4. Multiple endocrine neoplasia (MEN) type 1, 2 or...

A Proposed Grading Scheme for Medullary Thyroid Carcinoma Based on Proliferative Activi...
https://doi.org/10.1097/PAS.0000000000001505
The American Journal of Surgical Pathology; Fuchs TL, Nassour AJ et. al.

May 21st, 2020 - We investigated the prognostic value of a range of histologic parameters in medullary thyroid carcinoma (MTC) to design a grading system to predict overall survival. We assessed 76 patients with MTCs undergoing primary tumor resection for age, sex...

Cabozantinib as an emerging treatment for sarcoma.
https://doi.org/10.1097/CCO.0000000000000644
Current Opinion in Oncology; Schöffski P, Blay JY et. al.

May 19th, 2020 - Sarcomas are a diverse group of rare solid tumors with limited treatment options for patients with advanced, inoperable disease. Cabozantinib is a tyrosine kinase inhibitor currently approved for advanced renal cell, hepatocellular, and medullary ...

Chinese siblings with hereditary medullary thyroid carcinoma caused by RET mutation: im...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222469
BMC Endocrine Disorders; Huang Q, Hu A et. al.

May 15th, 2020 - Hereditary medullary thyroid carcinoma (MTC) is mainly caused by germline mutations in the RET proto-oncogene, which accounts for 20-30% of all MTC according to foreign studies. However, no English literatures have reported Chinese hereditary MTC....

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Guidelines  2 results

Consensus on management of advanced medullary thyroid carcinoma on behalf of the Workin...
https://doi.org/10.1007/s12094-015-1465-x
Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico; Grande E, Santamaría Sandi J et. al.

Dec 21st, 2015 - Of all thyroid cancers, <5 % are medullary (MTC). It is a well-characterized neuroendocrine tumor arising from calcitonin-secreting C cells, and RET gene plays a central role on its pathogeny. The electronic search was conducted using MEDLINE (Pub...

Revised American Thyroid Association guidelines for the management of medullary thyroid...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490627
Thyroid : Official Journal of the American Thyroid Association; Wells SA, Asa SL et. al.

Mar 26th, 2015 - The American Thyroid Association appointed a Task Force of experts to revise the original Medullary Thyroid Carcinoma: Management Guidelines of the American Thyroid Association. The Task Force identified relevant articles using a systematic PubMed...

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Clinicaltrials.gov  1,619 results

Early thyroidectomy in multiple endocrine neoplasia: a four decade experience.
https://doi.org/10.1530/ERC-20-0108
Endocrine-related Cancer; Grubbs EG, Lechan RM et. al.

May 28th, 2020 - Forty years ago, physicians caring for the J-kindred, a 100+ member family with multiple endocrine neoplasia type 2A (MEN2A), hypothesized that early thyroidectomy based on measurement of the biomarker calcitonin could cure patients at risk for de...

First proof of association between autoimmune polyglandular syndrome and multiple endoc...
https://doi.org/10.1507/endocrj.EJ20-0099
Endocrine Journal; Manso J, Censi S et. al.

May 28th, 2020 - Autoimmune Addison's disease (AAD) is a rare condition occurring either in isolation or associated with other autoimmune diseases as part of an autoimmune polyglandular syndrome (APS) type 1, 2 or 4. Multiple endocrine neoplasia (MEN) type 1, 2 or...

A Proposed Grading Scheme for Medullary Thyroid Carcinoma Based on Proliferative Activi...
https://doi.org/10.1097/PAS.0000000000001505
The American Journal of Surgical Pathology; Fuchs TL, Nassour AJ et. al.

May 21st, 2020 - We investigated the prognostic value of a range of histologic parameters in medullary thyroid carcinoma (MTC) to design a grading system to predict overall survival. We assessed 76 patients with MTCs undergoing primary tumor resection for age, sex...

Cabozantinib as an emerging treatment for sarcoma.
https://doi.org/10.1097/CCO.0000000000000644
Current Opinion in Oncology; Schöffski P, Blay JY et. al.

May 19th, 2020 - Sarcomas are a diverse group of rare solid tumors with limited treatment options for patients with advanced, inoperable disease. Cabozantinib is a tyrosine kinase inhibitor currently approved for advanced renal cell, hepatocellular, and medullary ...

Chinese siblings with hereditary medullary thyroid carcinoma caused by RET mutation: im...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222469
BMC Endocrine Disorders; Huang Q, Hu A et. al.

May 15th, 2020 - Hereditary medullary thyroid carcinoma (MTC) is mainly caused by germline mutations in the RET proto-oncogene, which accounts for 20-30% of all MTC according to foreign studies. However, no English literatures have reported Chinese hereditary MTC....

see more →

News  37 results

BLU-667: New Hope for NSCLC and Medullary Thyroid Cancer
https://www.medscape.com/viewarticle/895225

Apr 15th, 2018 - CHICAGO — Point mutations or gene rearrangements in the receptor tyrosine kinase proto-oncogene RET have been seen in several tumors, including medullary thyroid carcinoma (MTC) and non–small cell lung cancer (NSCLC). However, there are no approve...

Scapular rash and endocrine neoplasia
https://www.mdedge.com/ccjm/article/150352/dermatology/scapular-rash-and-endocrine-neoplasia?channel=162
Muhammed Razmi T, MD, DNB, Debajyoti Chatterjee, MD et. al.

Nov 1st, 2017 - A woman in her 30s presented with an itchy skin-colored rash over her left scapular region that had first appeared 8 years earlier. It had started as itchy skin-colored papules that coalesced to a patch and later became hyperpigmented because of r.

Medullary Thyroid Cancer Surgical Recommendations Often Ignored
https://www.medscape.com/viewarticle/886330

Sep 28th, 2017 - Only about a third of patients with medullary thyroid carcinoma (MTC) receive the recommended initial treatment of a total thyroidectomy in addition to central neck lymph-node dissection, despite recommendations in guidelines to combine the two to...

Thyroid Ca: Initial Neck Dissection May Cut Recurrence Risk
https://www.medpagetoday.com/endocrinology/thyroid/68165

Sep 27th, 2017 - Action Points Among those with medullary thyroid carcinoma (MTC), lymph node dissection seemed to decrease local recurrences. Note that guidelines from the American Thyroid Association recommend all patients with known MTC undergo surgery to remov...

Renal cell carcinoma approval adds another notch to cabozantinib’s belt
https://www.mdedge.com/hematology-oncology/article/118588/genitourinary-cancer/renal-cell-carcinoma-approval-adds-another
Edited by Jame Abraham, MD et. al.

Nov 21st, 2016 - In April this year, the US Food and Drug Administration awarded regulatory approval to cabozantinib for the treatment of advanced renal cell carcinoma patients previously treated with anti-angiogenic therapy. 1 The small-molecule inhibitor, which.

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