ALLMedicine™ Autoimmune Thyroid Disease Center

Sep 9th, 2021 - The programmed cell death-1 (PD-1)/PD ligand pathway plays a key role in the maintenance of peripheral tolerance by enhancing the suppressive activity of regulatory T (Treg) cells. The promoter activity of the A allele of PD1 rs36084323 G/A polymo...

Sep 3rd, 2021 - Vitamin A is a factor that suppresses immune responses, including Th1 and Th17 responses. However, there has been no report showing the association between vitamin A-related genes (CYP26B1, RARB and RARG) and the prognosis of autoimmune thyroid di...

Jul 31st, 2021 - Autoimmune thyroid disease (AITD) is an inherited, complex gene- and immune-related disorder that mainly includes Graves' disease (GD) and Hashimoto's thyroiditis (HT). Psoriasis susceptibility 1 candidate 1 (PSORS1C1) is a susceptibility gene ass...

Jul 21st, 2021 - Background: Autoimmune diseases tend to cluster in the same individual or in families. Four types of autoimmune polyglandular syndromes (APS) have been described based on the combination of endocrine and/or non-endocrine autoimmune diseases. In pa...

Jul 18th, 2021 - Histone deacetylases (HDACs) and histone acetyltransferases (HAT) have an important role in the regulation of gene transcription as well as in the development and function of CD4 +Foxp3 + T regulatory (Treg) cells. Since others and we have previou...

Aug 24th, 2015 - Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone. In the United States and other areas of adequate iodine intake, autoimmune thyroid disease (Hashimoto disease) is the most common cause of hypothyroidism; ...