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About 14,428 results

ALLMedicine™ Hypothyroidism Center

Research & Reviews  4,430 results

Retrospective study of the influence of hypothyroidism on liver function before radioio...
https://doi.org/10.1136/bmjopen-2020-045562
BMJ Open; Ji Y, Zheng W et. al.

Jan 20th, 2022 - The aim of the present study is to investigate the risk factors for hepatic dysfunction before radioiodine therapy in patients with differentiated thyroid cancer (DTC). 996 patients (314 men, 682 women; age of 45.07±12.98 years) with postoperative...

Primary hypothyroidism and quality of life.
https://doi.org/10.1038/s41574-021-00625-8 10.1089/thy.2021.0304 10.1111/cen.14473
Nature Reviews. Endocrinology; Hegedüs L, Bianco AC et. al.

Jan 20th, 2022 - In the 1970s, treatment with thyroid extract was superseded by levothyroxine, a synthetic L form of tetraiodothyronine. Since then, no major innovation has emerged for the treatment of hypothyroidism. The biochemical definition of subclinical hypo...

Congenital hypothyroidism and hyperthyroidism alters adrenal gene-expression, developme...
https://doi.org/10.1089/thy.2021.0535
Thyroid : Official Journal of the American Thyroid Associ... Patyra K, Löf C et. al.

Jan 20th, 2022 - The human adrenal cortex undergoes several rapid remodeling steps during its lifetime. In rodents, similar remodeling occurs postnatally in the 'X-zone' layer via unknown mechanisms. Furthermore, little is known regarding the impact of thyroid hor...

Pediatric Hypothyroidism
http://emedicine.medscape.com/article/922777-overview

Jan 18th, 2022 - Practice Essentials Hypothyroidism is among the most common endocrine diseases. Congenital hypothyroidism most frequently results from agenesis, dysplasia, or ectopy of the thyroid; however, it is also caused by autosomal recessive defects in the ...

Cushing disease due to a somatic USP8 mutation in a patient with evolving pituitary hor...
https://doi.org/10.20945/2359-3997000000428
Archives of Endocrinology and Metabolism; Labello JH, Benedetti AFF et. al.

Jan 15th, 2022 - We present the unique case of an adult Brazilian woman with severe short stature due to growth hormone deficiency with a heterozygous G to T substitution in the donor splice site of intron 3 of the growth hormone 1 (GH1) gene (c.291+1G>T). In this...

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Guidelines  12 results

Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035928
Thyroid : Official Journal of the American Thyroid Associ... Jonklaas J, Bianco AC et. al.

Dec 6th, 2020 - Background: Fourteen clinical trials have not shown a consistent benefit of combination therapy with levothyroxine (LT4) and liothyronine (LT3). Despite the publication of these trials, combination therapy is widely used and patients reporting ben...

Congenital Hypothyroidism: A 2020-2021 Consensus Guidelines Update-An ENDO-European Ref...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001676
Thyroid : Official Journal of the American Thyroid Associ... van Trotsenburg P, Stoupa A et. al.

Dec 5th, 2020 - Background: An ENDO-European Reference Network (ERN) initiative was launched that was endorsed by the European Society for Pediatric Endocrinology and the European Society for Endocrinology with 22 participants from the ENDO-ERN and the two societ...

Thyroid Disease in Pregnancy: ACOG Practice Bulletin, Number 223.
https://doi.org/10.1097/AOG.0000000000003893
Obstetrics and Gynecology;

May 23rd, 2020 - Both thyrotoxicosis and hypothyroidism are associated with adverse pregnancy outcomes. There also is concern about the effect of overt maternal thyroid disease on fetal development. In addition, medications that affect the maternal thyroid gland c...

Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline.
https://doi.org/10.1136/bmj.l2006
BMJ (Clinical Research Ed.); Bekkering GE, Agoritsas T et. al.

May 16th, 2019 - What are the benefits and harms of thyroid hormones for adults with subclinical hypothyroidism (SCH)? This guideline was triggered by a recent systematic review of randomised controlled trials, which could alter practice. Current guidelines tend t...

Palliative and supportive care in head and neck cancer: United Kingdom National Multidi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873917
The Journal of Laryngology and Otology; Cocks H, Ah-See K et. al.

Nov 15th, 2016 - This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. It provides recommendations on the assessments and interventions for this group of patients receiving palliative...

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Drugs  378 results see all →

Clinicaltrials.gov  103 results

Obstructive Sleep Apnoea in Sarcoidosis
https://clinicaltrials.gov/ct2/show/NCT04156789

Jan 14th, 2022 - Sarcoidosis is a multisystemic granulomatous disease of unknown origin. Fatigue is a common problem in sarcoidosis affecting between 50% and 80% of patients, and thus represents a major impairment of their quality of life. The findings of recent s...

Quality of Life Among Egyptian Hypothyroid Patients
https://clinicaltrials.gov/ct2/show/NCT05143918

Dec 20th, 2021 - Hypothyroidism is an underactive thyroid gland. Hypothyroidism means that the thyroid gland can't make enough thyroid hormone to keep the body running normally. People are hypothyroid if they have too little thyroid hormone in the blood. Common ca...

Evaluation of Patients With Thyroid Disorders
https://clinicaltrials.gov/ct2/show/NCT00001159

Dec 16th, 2021 - Patients with thyroid function abnormalities (hyperthyroidism, hypothyroidism) are studied and treated in this protocol. Patients undergo routine history and physical examination, standard endocrine blood and urine tests, a standard TRH test, thyr...

Biosignals by Wearables in Thyroid Dysfunction
https://clinicaltrials.gov/ct2/show/NCT04806269

Nov 11th, 2021 - An algorithm to predict thyroid dysfunction using heart rate and activity data from wearables was generated based on our previous clinical studies. This study was conducted to collect more data to advance the algorithm. Patients with thyroid dysfu...

The Effect of Dietary Supplements for Pregnant Women on Levothyroxine Absorption
https://clinicaltrials.gov/ct2/show/NCT04988802

Oct 20th, 2021 - Hypothyroidism is a common disease that is successfully treated with the replacement of thyroid hormones in the form of levothyroxine. Levothyroxine is drug used in the first line of substitution therapy because it appropriately mimics physiologic...

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News  809 results

Neoadjuvant Nivolumab/Ipilimumab Produces High pCR Rate in MSI/dMMR Oeso-Gastric Adenocarcinoma
https://www.onclive.com/view/neoadjuvant-nivolumab-ipilimumab-produces-high-pcr-rate-in-msi-dmmr-oeso-gastric-adenocarcinoma

Jan 20th, 2022 - Neoadjuvant nivolumab (Opdivo) plus ipilimumab (Yervoy) followed by adjuvant nivolumab elicited a pathologic complete response (pCR) rate of 59% in patients with resectable microsatellite instable (MSI)/mismatch repair deficient (dMMR) oeso-gastri...

Nivolumab Continues to Elicit Durable Responses in Advanced Hepatocellular Carcinoma
https://www.onclive.com/view/nivolumab-continues-to-elicit-durable-responses-in-advanced-hepatocellular-carcinoma

Jan 14th, 2022 - Nivolumab (Opdivo) elicited a prolonged clinical benefit in patients with advanced hepatocellular carcinoma (HCC) regardless of prior sorafenib (Nexavar) according to 5-year follow-up data from 2 cohorts of the phase 1/2 CheckMate040 trial (NCT016...

FDA Accepts BLA for Tislelizumab in Esophageal Squamous Cell Carcinoma
https://www.onclive.com/view/fda-accepts-bla-for-tislelizumab-in-esophageal-squamous-cell-carcinoma

Jan 14th, 2022 - The FDA has accepted for review a biologics license application (BLA) for tislelizumab (BGB-A317) as a potential therapeutic option in patients with unresectable recurrent locally advanced or metastatic esophageal squamous cell carcinoma (ESCC) fo...

Pembrolizumab Plus Enzalutamide Continues to Produce Antitumor Activity in Abiraterone Acetate-Pretreated mCRPC
https://www.onclive.com/view/pembrolizumab-plus-enzalutamide-continues-to-produce-antitumor-activity-in-abiraterone-acetate-pretreated-mcrpc

Jan 11th, 2022 - The combination of pembrolizumab (Keytruda) and enzalutamide (Xtandi) continued to demonstrate antitumor activity in patients with metastatic castration-resistant prostate cancer (mCRPC) who were previously treated with abiraterone acetate (Zytiga...

Sabatolimab Demonstrates Durable Clinical Benefits in Patients With AML, High-Risk MDS
https://www.onclive.com/view/sarbatolimab-demonstrates-durable-clinical-benefits-in-patients-with-aml-high-risk-mds

Dec 16th, 2021 - Sabatolimab (MBG453), an investigational TIM-3 monoclonal antibody, induced a median duration of response (DOR) greater than 1 year for patients with very high/high-risk myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) when used in ...

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Patient Education  39 results see all →