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About 22,912 results

ALLMedicine™ Hypercholesterolemia Center

Research & Reviews  8,791 results

Implementation of a Machine-Learning Algorithm in the Electronic Health Record for Targ...
https://doi.org/10.1161/CIRCOUTCOMES.120.007641
Circulation. Cardiovascular Quality and Outcomes; Sheth S, Lee P et. al.

Jun 10th, 2021 - Implementation of a Machine-Learning Algorithm in the Electronic Health Record for Targeted Screening for Familial Hypercholesterolemia: A Quality Improvement Study.|2021|Sheth S,Lee P,Bajaj A,Cuchel M,Hajj J,|

Redox regulation of hemodynamics response to diadenosine tetraphosphate an agonist of P...
https://doi.org/10.14814/phy2.14888
Physiological Reports; Dąbkowski K, Kreft E et. al.

Jun 10th, 2021 - Hypercholesterolemia and oxidative stress may lead to disturbances in the renal microvasculature in response to vasoactive agents, including P2 receptors (P2R) agonists. We investigated the renal microvascular response to diadenosine tetraphosphat...

Factors Associated with Carotid Atherosclerosis and Achilles Tendon Thickness in Japane...
https://doi.org/10.5551/jat.62925
Journal of Atherosclerosis and Thrombosis; Ogura M, Harada-Shiba M et. al.

Jun 10th, 2021 - Familial hypercholesterolemia (FH) is characterized by high low-density lipoprotein (LDL) cholesterol levels, xanthomas including Achilles tendon thickening, and premature coronary artery disease (CAD). Carotid intima-media thickness (IMT) is a we...

Rosuvastatin and ezetimibe for the treatment of dyslipidemia and hypercholesterolemia.
https://doi.org/10.1080/14779072.2021.1940959
Expert Review of Cardiovascular Therapy; Boutari C, Karagiannis A et. al.

Jun 9th, 2021 - Introduction: Statins are powerful lipid-lowering agents which reduce cardiovascular (CV)-related morbidity and mortality. However, a large proportion of patients cannot attain the target low density lipoprotein cholesterol (LDL-C) levels, despite...

Measurement of Achilles Tendon Thickness is a Key for International Harmonization in Cl...
https://doi.org/10.5551/jat.ED180
Journal of Atherosclerosis and Thrombosis; Yokoyama S

Jun 7th, 2021 - Measurement of Achilles Tendon Thickness is a Key for International Harmonization in Clinical Diagnosis of Familial Hypercholesterolemia.|2021|Yokoyama S,|

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Guidelines  27 results

Esperion Announces FDA Approval of NEXLETOL™ (bempedoic acid) Tablet, an Oral, Once-Daily, Non-Statin LDL-Cholesterol Lowering Medicine
https://esperion.gcs-web.com/node/11206/pdf

Feb 24th, 2020 - Esperion announced today that the U.S. Food and Drug Administration (FDA) approved NEXLETOL™ (bempedoic acid) tablet, an oral, once-daily, non-statin LDL-Cholesterol (LDL-C) lowering medicine. NEXLETOL is indicated as an adjunct to diet and maxima...

Statin Use and the Site-Specific Risk of Colorectal Cancer in Individuals with Hypercholesterolemia from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS)
https://www.sciencedirect.com/science/article/pii/S0939475319301164?via%3Dihub
Nutrition, Metabolism and Cardiovascular Diseases; Lee,J.,et al

Apr 12th, 2019 - Background and Aims We investigated the association between statin use and site-specific risk of colorectal cancer in individuals with hypercholesterolemia. Methods and Results This study is based on the National Health Insurance Service-National...

Lipid levels and the risk of hemorrhagic stroke among women
https://n.neurology.org/content/early/2019/04/10/WNL.0000000000007454
Rist,P.,et al

Apr 9th, 2019 - Objective To examine the association between lipid levels and hemorrhagic stroke risk among women. Methods We performed a prospective cohort study among 27,937 women enrolled in the Women's Health Study with measured total cholesterol, low-densit...

Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Up...
https://doi.org/10.1016/j.cjca.2018.09.005
The Canadian Journal of Cardiology; Brunham LR, Ruel I et. al.

Dec 11th, 2018 - Familial hypercholesterolemia (FH) is the most common monogenic disorder causing premature atherosclerotic cardiovascular disease. It affects 1 in 250 individuals worldwide, and of the approximately 145,000 Canadians estimated to have FH, most are...

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of ...
http://www.onlinejacc.org/content/early/2018/11/02/j.jacc.2018.11.003
Grundy, S.,et al

Nov 9th, 2018 - The recommendations listed in the present guideline are, whenever possible, evidence based. An initial extensive evidence review, which included literature derived from research involving human subjects, published in English, and indexed in MEDLIN.

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Drugs  1,911 results see all →

Clinicaltrials.gov  11,369 results

Real-world PCSK9i Data in FH Reveal Conundrum of Reimbursement
https://www.medscape.com/viewarticle/953408

Jun 17th, 2021 - Patients with familial hypercholesterolemia (FH), particularly those with heterozygous FH, see their low-density-lipoprotein (LDL) cholesterol levels slashed with evolocumab (Repatha) and maintained out to 2 years, suggests data from the HEYMANS r...

Simvastatin - simvastatin tablet, film coated-REMEDYREPACK INC.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b6737b25-0c4f-4131-ba23-b0f2252a18ea

Jun 15th, 2021 - Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. Drug therapy is indicated as an a...

Rosuvastatin calcium - rosuvastatin calcium tablet, film coated-REMEDYREPACK INC.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=11fad602-16c2-4c1f-bdf1-867d95f063ca

Jun 14th, 2021 - Pediatric use information for patients 7 to 17 years of age is approved for AstraZeneca’s CRESTOR (rosuvastatin calcium) tablets. However, due to AstraZeneca’s marketing exclusivity rights, this drug product is not labeled with that pediatric info...

Atorvastatin calcium - atorvastatin calcium tablet, film coated-MSN LABORATORIES PRIVATE LIMITED
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=99eba422-e3d9-4e49-b4b4-3be6af258baa

Jun 14th, 2021 - Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. Drug therapy is recommended as an...

Fenofibrate - fenofibrate tablet, film coated-Preferred Pharmaceuticals Inc.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ceedfb5d-8a04-4b4b-852f-1eac963f96a3

Jun 14th, 2021 - Fenofibrate tablets are a peroxisome proliferator-activated receptor (PPAR) alpha agonist indicated as an adjunct to diet: •To reduce elevated LDL-C, Total-C, TG and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia ...

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News  809 results

Real-world PCSK9i Data in FH Reveal Conundrum of Reimbursement
https://www.medscape.com/viewarticle/953408

Jun 17th, 2021 - Patients with familial hypercholesterolemia (FH), particularly those with heterozygous FH, see their low-density-lipoprotein (LDL) cholesterol levels slashed with evolocumab (Repatha) and maintained out to 2 years, suggests data from the HEYMANS r...

Limited-Variant Screening Tests Often Miss Familial Hypercholesterolemia
https://www.medscape.com/viewarticle/952069

May 30th, 2021 - NEW YORK (Reuters Health) - Two-thirds of cases of familial hypercholesterolemia (FH) would be missed by relying on array-based genetic tests that screen for only a limited number of variants, according to a new study. "Negative findings on a limi...

An Expert's Guide to Managing Familial Hypercholesterolemia
https://www.medscape.com/viewarticle/948546

Apr 20th, 2021 - This transcript has been edited for clarity. Hi. I'm Seth Baum, a preventive cardiologist and clinical lipidologist in Boca Raton, Florida. I'm also the past president of the American Society for Preventive Cardiology and on the faculty at the Flo...

An Expert's Guide to Managing Familial Hypercholesterolemia
https://www.medscape.com/viewarticle/948546?src=sapfe

Apr 20th, 2021 - This transcript has been edited for clarity. Hi. I'm Seth Baum, a preventive cardiologist and clinical lipidologist in Boca Raton, Florida. I'm also the past president of the American Society for Preventive Cardiology and on the faculty at the Flo...

FDA Okays New Indication for Alirocumab in Homozygous FH
https://www.medscape.com/viewarticle/948580

Mar 31st, 2021 - The US Food and Drug Administration has approved alirocumab (Praluent, Regeneron Pharmaceuticals) injection as add-on therapy for adults with homozygous familial hypercholesterolemia, the agency announced. The proprotein convertase subtilisin/kexi...

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Patient Education  5 results see all →