ALLMedicine™ Hypertension Center

Apr 21st, 2021 - Background: The tricarboxylic (TCA) acid cycle provides the energy needed for regulatory functions in the cardio-renal system. Recently, a genetic defect in the TCA cycle enzyme, fumarase hydratase, altered L-arginine metabolism and exacerbated hy...

Apr 21st, 2021 - Alanine:glyoxylate aminotransferase 2 (AGXT2; EC 2.6.1.44) is the only enzyme that degrades the R-form of 3-aminoisobutyrate, an intermediate metabolite of thymine. AGXT2, as well as diaminoarginine dimethylaminohydrolase 1 (DDAH1; EC 3.5.3.18), w...

Apr 21st, 2021 - Circulating monocytes and tissue macrophages play complex roles in the pathogenesis of hypertension and the resulting target organ damage. In this study, we observed alterations in the monocyte phenotype and inflammatory state of hypertensive pati...

Apr 21st, 2021 - At present, there is no generally accepted comprehensive prognostic risk prediction model for medically treated chronic thromboembolic pulmonary hypertension (CTEPH) patients. Consecutive medically treated CTEPH patients were enrolled in a nationa...

Apr 21st, 2021 - Obesity and multimorbidity are more prevalent among U.S. racial/ethnic minority groups. Evaluating racial/ethnic disparities in disease accumulation according to body-mass index (BMI) may guide interventions to reduce multimorbidity burden in vuln...

Mar 8th, 2021 - Studies show that certain common medical conditions put people at higher risk for severe illness from COVID-19. These include metabolic disorders like type 2 diabetes and obesity, as well as heart conditions like high blood pressure (hypertension)...

Nov 24th, 2020 - Cardiovascular disease (CVD) is a leading cause of death in the US. Known modifiable risk factors for CVD include smoking, overweight and obesity, diabetes, elevated blood pressure or hypertension, dyslipidemia, lack of physical activity, and unhe...

Nov 10th, 2020 - Prevalence of hypertension (both primary and secondary) in children and adolescents in the US ranges from 3% to 4%. Primary hypertension in children and adolescents occurs primarily in children older than 13 years and has no known cause but is ass...

Nov 8th, 2020 - In patients with connective tissue diseases, such as systemic sclerosis (SSc), pulmonary hypertension (PH) remains one of the leading causes of morbidity and mortality. In her lecture on Friday, Nov. 6, Pulmonary Hypertension: An Update, Mardi Gom...

Aug 31st, 2020 - In January 2020, the U.S. Department of Veterans Affairs (VA) and the U.S. Department of Defense (DoD) approved a joint clinical practice guideline for the diagnosis and management of hypertension in the primary care setting. The VA/DoD Evidence-B...

Apr 21st, 2021 - Background: The tricarboxylic (TCA) acid cycle provides the energy needed for regulatory functions in the cardio-renal system. Recently, a genetic defect in the TCA cycle enzyme, fumarase hydratase, altered L-arginine metabolism and exacerbated hy...

Apr 21st, 2021 - Alanine:glyoxylate aminotransferase 2 (AGXT2; EC 2.6.1.44) is the only enzyme that degrades the R-form of 3-aminoisobutyrate, an intermediate metabolite of thymine. AGXT2, as well as diaminoarginine dimethylaminohydrolase 1 (DDAH1; EC 3.5.3.18), w...

Apr 21st, 2021 - Circulating monocytes and tissue macrophages play complex roles in the pathogenesis of hypertension and the resulting target organ damage. In this study, we observed alterations in the monocyte phenotype and inflammatory state of hypertensive pati...

Apr 21st, 2021 - At present, there is no generally accepted comprehensive prognostic risk prediction model for medically treated chronic thromboembolic pulmonary hypertension (CTEPH) patients. Consecutive medically treated CTEPH patients were enrolled in a nationa...

Apr 21st, 2021 - Obesity and multimorbidity are more prevalent among U.S. racial/ethnic minority groups. Evaluating racial/ethnic disparities in disease accumulation according to body-mass index (BMI) may guide interventions to reduce multimorbidity burden in vuln...

Apr 20th, 2021 - NEW YORK (Reuters Health) - The use of beta-blockers as a blood pressure treatment could increase the risk of heart disease for HIV patients, according to an analysis of data from the U.S. Veterans Health Administration. Researchers reviewed recor...

Apr 14th, 2021 - Only about a quarter of patients with ocular hypertension lose peripheral vision, so clinicians should not recommend treatment to everyone with this condition, a long-term study suggests. The 20-year results of the phase 3 Ocular Hypertension Stud...

Apr 12th, 2021 - This transcript has been edited for clarity. Ileana L. Piña, MD, MPH: Hello. I'm Ileana Piña, professor of medicine at Wayne State and at Central Michigan University. I'm a heart failure transplant cardiologist, and this is my blog. We often have ...

Apr 12th, 2021 - Takeaway The use of angiotensin-converting enzyme (ACE) inhibitors in hypertensive patients was not associated with an increased risk of suspected or confirmed COVID-19, whereas the use of angiotensin II receptor blockers (ARBs) was associated wit...

Apr 11th, 2021 - Sodium restriction is one of the most common dietary recommendations made by US physicians. But there is lack of consensus on how low to go and whether cutting salt can ever be harmful. When our evolutionary ancestors left the salty environment of...