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ALLMedicine™ Inner Ear Center

Research & Reviews  2,016 results

Deafness-in-a-dish: modeling hereditary deafness with inner ear organoids.
https://doi.org/10.1007/s00439-021-02325-9 10.1038/ng0297-157 10.1001/archinte.168.14.1522 10.1086/321277 10.1086/375122 10.1093/hmg/ddg358 10.1523/JNEUROSCI.1163-06.2006 10.1093/hmg/10.16.1709 10.15252/emmm.201809396 10.1002/cm.21227 10.1038/s41586-019-1711-4 10.1038/mp.2016.158 10.1016/j.stem.2009.11.013 10.1136/bmj.323.7312.533 10.1038/s41586-020-1962-0 10.1038/83667 10.1086/522090 10.1086/316954 10.1186/1471-213X-10-89 10.1038/nature05950 10.1016/j.ijporl.2009.01.012 10.1093/hmg/9.9.1443 10.1371/journal.pgen.1005793 10.1038/nbt.3445 10.1016/j.neurobiolaging.2017.09.034 10.1242/dev.150458 10.1016/j.omtm.2020.03.010 10.1038/nature11415 10.1038/cdd.2016.16 10.1007/s13238-016-0247-8 10.1038/s41419-018-0488-y 10.1126/science.1231143 10.1126/science.3381100 10.1093/geront/43.5.661 10.1371/journal.pone.0162508 10.1038/ejhg.2012.128 10.1152/jn.00746.2003 10.7554/eLife.05098 10.1073/pnas.1605537113 10.1038/nature09941 10.1121/1.5132553 10.1002/lary.25409 10.1074/jbc.M110.190652 10.1387/ijdb.103177af 10.1016/j.heares.2019.02.006 10.1093/deafed/enm067 10.1073/pnas.1610155113 10.1002/9780470515587.ch9 10.1038/ncomms9715 10.1387/ijdb.072365lf 10.1200/JCO.2016.66.8822 10.1038/nbt.3443 10.1016/S0140-6736(21)00516-X 10.1542/peds.2014-1173 10.2105/AJPH.2016.303299 10.1093/ageing/afr155 10.5319/wjo.v3.i1.1 10.1038/s41591-019-0500-9 10.1007/s10162-002-3022-x 10.1016/j.ydbio.2018.08.013 10.1016/j.scr.2021.102295 10.1121/1.5131344 10.1055/s-0037-1601885 10.1016/j.celrep.2016.12.020 10.1016/j.reth.2018.11.001 10.3390/cells8050458 10.1038/nature11826 10.1016/0378-5955(87)90137-7 10.1038/nbt.2051 10.1007/s00441-014-2029-z 10.1038/s41419-018-0967-1 10.1177/000348941212101201 10.1002/(SICI)1097-0177(199812)213:4<486::AID-AJA13>3.0.CO;2-L 10.3389/fnagi.2015.00033 10.1002/cncr.32698 10.1155/2016/6137541 10.1016/s0378-5955(03)00338-1 10.1038/nature12298 10.1038/nbt.3840 10.1038/s41467-020-16113-y 10.3389/fnmol.2019.00316 10.1038/ng842 10.1016/j.stemcr.2015.12.009 10.1016/j.ydbio.2005.01.015 10.1038/nature12517 10.1007/BF00698787 10.1007/BF00309683 10.1001/jamaoto.2014.42 10.1073/pnas.0800387105 10.1007/s00420-015-1083-5 10.1001/jamainternmed.2013.1868 10.1177/0194599820962475 10.1038/ng0697-188 10.1038/ng1197-268 10.1038/ncomms11508 10.1371/journal.pone.0064906 10.1126/science.1232033 10.1016/j.stemcr.2019.05.005 10.1038/nbt.1890 10.1242/bio.038083 10.1016/j.celrep.2017.01.066 10.1086/323156 10.1038/nature22312 10.1038/nbt.3392 10.1016/j.ejmg.2011.06.001 10.1038/nature01262 10.1016/j.stem.2012.05.009 10.1038/nbt.1615 10.1136/jmg.2004.018523 10.1016/j.stem.2009.05.015 10.1007/s10162-007-0106-7 10.1242/dev.137133 10.1016/j.cell.2010.03.035 10.1038/cddis.2012.56 10.1002/stem.609 10.3389/fncel.2017.00409 10.1038/s41467-018-06033-3 10.1038/ng0298-171 10.1002/lio2.388 10.1016/j.tibtech.2020.10.013 10.1016/j.celrep.2019.02.053 10.1101/gad.1013302 10.1101/gad.1303905 10.1089/scd.2014.0033 10.1371/journal.pgen.1004432 10.1073/pnas.0308475101 10.1126/science.3381101 10.1038/nature07935 10.1053/j.gastro.2011.07.050 10.1089/scd.2017.0142 10.1016/j.heares.2009.03.008 10.1038/83768 10.1016/j.ydbio.2005.12.021 10.1523/JNEUROSCI.1064-12.2012 10.1016/j.stemcr.2017.11.013 10.1016/j.cell.2018.07.007 10.1038/nature09691 10.1016/j.cell.2019.05.031 10.1016/j.cell.2018.07.008 10.1016/0012-1606(90)90251-d 10.1016/j.cell.2006.07.024 10.1016/j.cell.2007.11.019 10.1038/nature15695 10.5966/sctm.2015-0252 10.1016/j.stemcr.2019.05.014 10.1038/nature05972 10.1097/AUD.0000000000000219 10.3390/genes11101122 10.1126/science.279.5358.1950 10.1038/s41418-020-00678- 10.1136/jmg.40.12.879 10.1016/j.heares.2013.05.003 10.1038/374060a0 10.1038/ng0697-191 10.1016/j.cell.2019.05.006 10.1016/j.stem.2018.10.010 10.1186/1471-2202-4-2 10.1073/pnas.2025196118 10.1016/j.arr.2020.101042 10.1111/j.1365-2184.2010.00669.x 10.1038/7693 10.1128/JVI.02948-15 10.1242/dev.00628 10.1016/j.biocel.2018.01.013 10.1086/379286
Human Genetics; Romano DR, Hashino E et. al.

Aug 4th, 2021 - Sensorineural hearing loss (SNHL) is a major cause of functional disability in both the developed and developing world. While hearing aids and cochlear implants provide significant benefit to many with SNHL, neither targets the cellular and molecu...

Endoscopy-Assisted Transmeatal Cochlear Implantation in Multiple Ear Deformities.
https://doi.org/10.5152/iao.2021.8885
The Journal of International Advanced Otology; Li YL, Lee WT et. al.

Jul 27th, 2021 - To study congenitally deaf children with inner ear malformations that usually have comorbid anomalous facial nerves and middle ear deformities. To determine the feasibility of endoscopy-assisted transmeatal cochlear implantation with the purpose o...

The differentiation status of hair cells that regenerate naturally in the vestibular in...
https://doi.org/10.1523/JNEUROSCI.3127-20.2021
The Journal of Neuroscience : the Official Journal of The... González-Garrido A, Pujol R et. al.

Jul 25th, 2021 - Aging, disease and trauma can lead to loss of vestibular hair cells and permanent vestibular dysfunction. Previous work showed that, following acute destruction of ∼95% of vestibular hair cells in adult mice, ∼20% regenerate naturally (without exo...

Allergy, Immunotherapy, and Alternative Treatments for Dizziness.
https://doi.org/10.1016/j.otc.2021.05.020
Otolaryngologic Clinics of North America; Derebery MJ, Christopher L

Jul 24th, 2021 - Allergic reactions may result in central symptoms of dizziness, including nonspecific chronic imbalance, Meniere's disease, and autoimmune inner ear disease. Excepting first-generation antihistamines, and short-term use of steroids, most pharmacot...

Local magnetic delivery of recombinant adeno-associated virus AAV2(quad Y-F) mediated b...
https://doi.org/10.1016/j.ymthe.2021.07.013
Molecular Therapy : the Journal of the American Society O... Mukherjee S, Kuroiwa M et. al.

Jul 24th, 2021 - Moderate noise exposure may cause acute loss of cochlear synapses without affecting the cochlear hair cells and hearing threshold; thus, it remains "hidden" to standard clinical tests. This cochlear synaptopathy is one of the main pathologies of n...

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Guidelines  3 results

Clinical Practice Guideline: Ménière's Disease.
https://doi.org/10.1177/0194599820909438
Otolaryngology--head and Neck Surgery : Official Journal ... Basura GJ, Adams ME et. al.

Apr 9th, 2020 - Ménière's disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low- to midfrequency sensorineural hearing loss in the affected ear before, during, or after one of the epi...

Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update).
https://doi.org/10.1177/0194599816689667
Otolaryngology--head and Neck Surgery : Official Journal ... Bhattacharyya N, Gubbels SP et. al.

Mar 2nd, 2017 - Objective This update of a 2008 guideline from the American Academy of Otolaryngology-Head and Neck Surgery Foundation provides evidence-based recommendations to benign paroxysmal positional vertigo (BPPV), defined as a disorder of the inner ear c...

Screening for Hearing Loss in Older Adults - Clinical Summary
https://allmedx.com/USPSTFPDF/adulthearsum.pdf

Aug 10th, 2012 - SCREENING FOR HEARING LOSS IN OLDER ADULTS CLINICAL SUMMARY OF U.S. PREVENTIVE SERVICES TASK FORCE RECOMMENDATION Population Asymptomatic adults aged 50 years or older Recommendation No recommendation. Grade: I (Insufficient Evidenc...

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Clinicaltrials.gov  50 results

Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases Including Juvenile Dermatomyositis
https://clinicaltrials.gov/ct2/show/NCT00059748

Apr 22nd, 2020 - Autoinflammatory multisystem diseases are a group of diseases that are characterized by recurrent episodes of systemic inflammation as well as organ specific inflammation that can involve the skin, eyes, joints, bones, serosal surfaces, inner ear,...

Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Healthy Subjects (HYDROPS)
https://clinicaltrials.gov/ct2/show/NCT02529475

Feb 10th, 2020 - This prospective study aims to better characterize inner ear's perilymphatic structures with Magnetic Resonance Imaging using contrast media and delayed injection in healthy subjects MR Perfusion Imaging will be assess in both cochlea as well Prim...

Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Patients With Meniere's Disease
https://clinicaltrials.gov/ct2/show/NCT02530931

Dec 27th, 2019 - This prospective study aims to better characterize inner ear's perilymphatic structures with Magnetic Resonance Imaging using contrast media and delayed injection in patient's with Meniere's disease. MR Perfusion Imaging will be assess in both coc...

AB-Intra- and Post-Operative Measures of Auditory Function
https://clinicaltrials.gov/ct2/show/NCT03685461

Dec 26th, 2019 - Background and Objectives of the Study Cochlear Implantation A cochlear implant (CI) is a prosthetic device for the inner ear that bypasses damaged inner ear hair cells and directly stimulates the auditory nerve, thereby providing audible sensatio...

Cochlear Implant Speech and Non-speech Sound Recognition
https://clinicaltrials.gov/ct2/show/NCT03661970

Oct 4th, 2019 - A cochlear implant (CI) is a small, complex electronic device used by the profoundly deaf or severely hard-of-hearing. The CI has two main components: 1. The externally worn microphone, sound processor and transmitter system; 2. The implanted rece...

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News  26 results

Implant Produces 'Remarkable Improvement' in Vestibular Disorder
https://www.medscape.com/viewarticle/946262

Feb 22nd, 2021 - An implanted device is showing promise in patients with bilateral vestibular hypofunction (BVH), a debilitating condition that significantly impairs balance. Early research suggests the modified cochlear implant placed in the inner ear of eight pa...

New Guideline to Improve Ménière's Disease Diagnosis, Treatment
https://www.medscape.com/viewarticle/928652

Apr 14th, 2020 - A new clinical practice guideline from the American Academy of Otolaryngology‒Head and Neck Surgery Foundation (AAO-HNSF) is providing evidence-based recommendations for the diagnosis and treatment of Ménière's disease. A disorder of the inner ear...

New Guideline to Improve Ménière's Disease Diagnosis, Treatment
https://www.staging.medscape.com/viewarticle/928652

Apr 14th, 2020 - A new clinical practice guideline from the American Academy of Otolaryngology‒Head and Neck Surgery Foundation (AAO-HNSF) is providing evidence-based recommendations for the diagnosis and treatment of Ménière's disease. A disorder of the inner ear...

At-Home Video Goggles Provide Early, Accurate Vertigo Diagnosis
https://www.medscape.com/viewarticle/913879

Jun 4th, 2019 - Specialized goggles measuring eye movements during an episode of vertigo may rapidly and accurately diagnose the type of vertigo the patient is experiencing, new research suggests. Investigators taught patients with recurrent vertigo to self-recor...

Docs Shouldn't Have to Do Everything
https://www.medpagetoday.com/hospitalbasedmedicine/workforce/77655?comment=true

Jan 28th, 2019 - The existing structure of preparing the healthcare workforce of the future is attracting increasing attention. Recently, in his MedPage Today "Revolution and Revelation" blog, Milton Packer deconstructed the traditional academic medical center as ...

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Patient Education  39 results see all →