ALLMedicine™ Inner Ear Center

Mar 27th, 2023 - We have developed 3D-printed microneedle technology for diagnostic aspiration of perilymph and intracochlear delivery of therapeutic agents. Single microneedle-mediated round window membrane (RWM) perforation does not cause hearing loss, heals wit...

Mar 26th, 2023 - Adeno-associated virus (AAV)-mediated inner ear gene therapy is a promising treatment option for hearing loss and dizziness. Several studies have shown that AAV-mediated inner ear gene therapy can be applied to various mouse models of hereditary h...

Mar 26th, 2023 - Stereocilia are actin-based cell protrusions of inner ear hair cells and are indispensable for mechanotransduction. Ankle links connect the ankle region of developing stereocilia, playing an essential role in stereocilia development. WHRN, PDZD7, ...

Mar 21st, 2023 - The present study aimed to evaluate binaural auditory skills in bimodal and bilateral pediatric cochlear implant (CI) users with incomplete partition type-II (IP-II) and to reveal the effect of IP-II on performance by comparing the results to pedi...

Mar 21st, 2023 - Hereditary hearing loss is one of the most common sensory disabilities affecting newborns (approximately 1/1000 live births)1. Currently, the main treatment options for patients with hereditary hearing loss include hearing aids and cochlear implan...

Apr 9th, 2020 - Ménière's disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low- to midfrequency sensorineural hearing loss in the affected ear before, during, or after one of the epi...

Mar 2nd, 2017 - Objective This update of a 2008 guideline from the American Academy of Otolaryngology-Head and Neck Surgery Foundation provides evidence-based recommendations to benign paroxysmal positional vertigo (BPPV), defined as a disorder of the inner ear c...

Aug 10th, 2012 - SCREENING FOR HEARING LOSS IN OLDER ADULTS CLINICAL SUMMARY OF U.S. PREVENTIVE SERVICES TASK FORCE RECOMMENDATION Population Asymptomatic adults aged 50 years or older Recommendation No recommendation. Grade: I (Insufficient Evidenc...

Mar 21st, 2023 - Hereditary hearing loss is one of the most common sensory disabilities affecting newborns (approximately 1/1000 live births)1. Currently, the main treatment options for patients with hereditary hearing loss include hearing aids and cochlear implan...

Mar 10th, 2023 - Benign paroxysmal positional vertigo (BPPV) is a common disorder of the inner ear that causes episodes of vertigo. BPPV occurs as a result of displacement of otoliths from their position on the utricle into one of the semicircular canals. Posterio...

Mar 8th, 2023 - INTRODUCTION AND BACKGROUND Disease background Testicular cancers are the most common malignancies in men aged between 18-35 years. Of those, seminoma is the most frequent as it accounts for about half of all testicular cancers. Seminoma is classi...

Mar 8th, 2023 - Hearing plays a vital role in the development of a child. Hearing is based on two main systems: the peripheral system and the central system. Peripheral hearing, which includes the outer, middle, and inner ear and the auditory nerve, can detect so...

Mar 6th, 2023 - Title: Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures and Discovery of Therapeutic Targets Study Description: Disorders of hearing instability remain poo...

Oct 19th, 2022 - Sodium thiosulfate (Pedmark) has shown promise as an ototoxicity-mediating agent in pediatric patients with solid tumors treated with cisplatin, according to Nilay Shah, MD. He noted that additional research is needed to determine the long-term ef...

Jul 20th, 2022 - Antihistamines are superior to benzodiazepines for the immediate treatment of vertigo, results of a new systematic review and meta-analysis suggest. But antihistamines and benzodiazepines are no better than other medications for the acute treatmen...

Jun 15th, 2022 - The cupboard in Nicolás Rascovan's microbial paleogenomics lab at Institut Pasteur in Paris, France, is filled up with cardboard boxes that look as if they were shipped from an office supply store. Yet, instead of pencils and Post-it notes, the bo...

May 23rd, 2022 - A single master gene has been identified that can program ear hairs and help restore hearing, according to Northwestern Medicine scientists. What to know: Scientists think they can now reprogram existing cells once they die to develop into the out...

Feb 9th, 2022 - Vijayakrishna Gadi, MD, PhD: I’m going to transition us to a different phase of the discussion that’s focused on treatment beyond the first line. Let’s say this patient who we just discussed gets good mileage out of this—3, 4 years of stable time....