About 4,360 results

ALLMedicine™ Acromegaly Center

Research & Reviews  1,423 results

Impact of the COVID-19 pandemic in the treatment of patients with acromegaly in a terti...
Archives of Endocrinology and Metabolism; de Jesus Nunes R, Masullo LF et. al.

Jun 28th, 2022 - The COVID-19 pandemic has profoundly disrupted health care worldwide. We aimed to evaluate the impact of the first COVID-19 wave on the treatment of our patients with acromegaly. A standard questionnaire was systematically applied to all patients ...

Covert actions of growth hormone: fibrosis, cardiovascular diseases and cancer.
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Nature Reviews. Endocrinology; Kopchick JJ, Basu R et. al.

Jun 25th, 2022 - Since its discovery nearly a century ago, over 100,000 studies of growth hormone (GH) have investigated its structure, how it interacts with the GH receptor and its multiple actions. These include effects on growth, substrate metabolism, body comp...

Growth Hormone

Jun 24th, 2022 - Reference Range Random growth hormone (GH) levels in a healthy person range as follows [1] : Men - < 5 ng/mL (mcg/L [SI units]) Women - < 10 ng/mL (mcg/L [SI units]) Newborns - 5-23 ng/mL (mcg/L [SI units]) 1 week - 2-27 ng/mL (mcg/L [SI units]) 1...

Growth Hormone

Jun 24th, 2022 - Reference Range Random growth hormone (GH) levels in a healthy person range as follows [1] : Men - < 5 ng/mL (mcg/L [SI units]) Women - < 10 ng/mL (mcg/L [SI units]) Newborns - 5-23 ng/mL (mcg/L [SI units]) 1 week - 2-27 ng/mL (mcg/L [SI units]) 1...

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Guidelines  5 results

Italian Society for the Study of Diabetes (SID)/Italian Endocrinological Society (SIE) ...
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Baroni MG, Giorgino F et. al.

Feb 26th, 2016 - Hyperglycemia is a common feature associated with states of increased growth hormone secretion and glucocorticoid levels. The purpose of these guidelines is to assist clinicians and other health care providers to take evidence-based therapeutic de...

Expert consensus document: A consensus on the medical treatment of acromegaly.
Nature Reviews. Endocrinology; Giustina A, Chanson P et. al.

Feb 26th, 2014 - In March 2013, the Acromegaly Consensus Group met to revise and update guidelines for the medical treatment of acromegaly. The meeting comprised experts skilled in the medical management of acromegaly. The group considered treatment goals covering...

American Association of Clinical Endocrinologists medical guidelines for clinical pract...
Endocrine Practice : Official Journal of the American Col... Katznelson L, Atkinson JL et. al.

Aug 24th, 2011 - American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly--2011 update.|2011|Katznelson L,Atkinson JL,Cook DM,Ezzat SZ,Hamrahian AH,|diagnosis,therapy,standards,trends,...

AME Position Statement on clinical management of acromegaly.
Journal of Endocrinological Investigation; Cozzi R, Baldelli R et. al.

Jan 23rd, 2010 - AME Position Statement on clinical management of acromegaly.|2010|Cozzi R,Baldelli R,Colao A,Lasio G,Zini M,|diagnosis,economics,epidemiology,therapy,

Guidelines for acromegaly management: an update.
The Journal of Clinical Endocrinology and Metabolism; Melmed S, Colao A et. al.

Feb 12th, 2009 - The Acromegaly Consensus Group reconvened in November 2007 to update guidelines for acromegaly management. The meeting participants comprised 68 pituitary specialists, including neurosurgeons and endocrinologists with extensive experience treating...

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Drugs  27 results see all →

Clinicaltrials.gov  176 results

Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess

Jun 24th, 2022 - Growth hormone excess is a rare and potentially lethal condition associated with hypersecretion of growth hormone (GH), usually by a pituitary tumor or hyperplasia. When it occurs prior to the complete fusion of growth plates, it leads to patholog...

Real-World Study (RWS) of Lanreotide Autogel (LAN) for the Treatment of Patients With Acromegaly in China

Jun 24th, 2022 - This study aims to assess the one-year effectiveness and safety of LAN among patients with acromegaly in China in routine clinical practice. In addition, the study is designed to understand the real-world treatment patterns and outcomes of LAN amo...

Genetic Studies of Insulin and Diabetes

Jun 24th, 2022 - Study Description: Insulin is the key hormone responsible for regulating the level of glucose in plasma. In several disease states (e.g., obesity, type 2 diabetes, and acromegaly), the target cells are resistant to insulin action. Insulin resistan...

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly

Jun 15th, 2022 - The purpose of this trial is to assess the efficacy and safety of CAM2029 in patients with acromegaly. Patients will be randomized to either CAM2029 or placebo administered subcutaneously once monthly during 6 months.

A Trial to Assess the Long-term Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly

Jun 15th, 2022 - The purpose of this trial is to assess the long-term safety of CAM2029 in patients with acromegaly. Patients will be administered CAM2029 subcutaneously once monthly during 12 months. Patients fulfilling trial NCT04076462 will be offered to contin...

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News  106 results

Practice Guidelines Highlights From the Past Year

Mar 8th, 2022 - Dr Douglas S. Paauw A 64-year-old woman is evaluated for fever, diarrhea, and abdominal pain. She was diagnosed with Clostridioides difficile 2 months ago and completed a 10-day course of vancomycin. Her stool toxin test is positive for Clostridio...

Practice guidelines highlights from past year
Douglas S. Paauw, MD

Mar 3rd, 2022 - A 64-year-old woman is evaluated for fever, diarrhea, and abdominal pain. She was diagnosed with Clostridioides difficile 2 months ago and completed a 10-day course of vancomycin.

Oral Octreotide Shows Promise as Alternative to Injections for Acromegaly

Jan 10th, 2022 - NEW YORK (Reuters Health) - Many patients with acromegaly may do as well on oral octreotide treatment as they do on injectable somatostatin receptor ligands (iSRLs), an industry-sponsored phase-3 trial suggests. Oral octreotide is the first oral m...

Association of Circulating IGF-I with Common Non-cancerous Conditions

Nov 15th, 2021 - Takeaway Circulating insulin-like growth factor-I (IGF-I) was associated with several common conditions (other than cancer), including a positive association with carpal tunnel syndrome and inverse associations with varicose veins and iron deficie...

FDA Eyes Oral Testosterone; Phase II Success for Novel Osteoporosis Tx

Mar 14th, 2021 - The FDA accepted a new drug application and set a review date of October 31 for Marius Pharmaceuticals' Kyzatrex, an oral testosterone undecanoate softgel, for primary and secondary male hypogonadism. The Endocrine Society released a new scientifi...

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Patient Education  7 results see all →