ALLMedicine™ Diarrhea Center

Aug 14th, 2022 - To evaluate the safety and efficacy of tisotumab vedotin-tftv (TV), a first-in-class vectorized anti-tissue factor (TF) antibody-drug conjugate (ADC), for the treatment of recurrent or metastatic cervical cancer. A literature search of ClinicalTri...

Aug 14th, 2022 - According to their selectivity for sodium-glucose cotransporters (SGLT) 1 and 2, gliflozins could be subdivided into two additional categories: pure SGLT2 inhibitors, which are highly selective for SGLT2, and dual SGLT1/2 inhibitors which, in addi...

Aug 13th, 2022 - (1) Background: This study aimed to investigate the existing water, sanitation, and hygiene (WASH) policy and practice of the study population and strengthen the evidence base by documenting changes in the WASH policy and practice over 3 years of ...

Aug 13th, 2022 - To investigate the effects and mechanisms of electroacupuncture (EA) at ST25 and ST37 on the intestinal low-grade inflammation (LGI) in rat model of Diarrhea-predominant irritable bowel syndrome (IBS-D). IBS-D model rats were established by acetic...

Aug 13th, 2022 - Extrauterine endometrial stromal sarcoma (EESS) is extremely rare, especially with the colorectum involvement. We describe 18F-FDG PET/CT findings of EESS in the sigmoid colon and rectum in a 46-year-old woman who complained diarrhea. 18F-FDG PET/...

Jun 24th, 2022 - Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder associated with significant disease burden. This American Gastroenterological Association Guideline is intended to support practitioners in decisions about the use of ...

May 19th, 2021 - Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent ...

May 13th, 2021 - Lactose intolerance (LI) is characterized by diarrhea, abdominal pain, or bloating occurring after lactose consumption in patients with lactose malabsorption. The National Institute of Health (NIH) proposed a double-blind placebo testing to identi...

Jul 18th, 2020 - Thanks to ready access to hydrogen breath testing, small intestinal bacterial overgrowth is now commonly diagnosed among individuals presenting with a variety of gastrointestinal and even non-gastrointestinal complaints and is increasingly implica...

Mar 7th, 2020 - The NCCN Guidelines for Management of Immunotherapy-Related Toxicities provide interdisciplinary guidance on the management of immune-related adverse events (irAEs) resulting from cancer immunotherapy. These NCCN Guidelines Insights describe sympt...

Aug 12th, 2022 - This is a randomized, double-blind placebo controlled study to assess for safety, tolerability and nutritional impact of oral serum bovine immunoglobulin (SBI) on pediatric patients and young adults with inflammatory bowel disease (IBD) as assesse...

Aug 12th, 2022 - Hypothesis: AZVUDINE has therapeutic potential and safety profile for the treatment of patients infected with SARS-CoV-2. Goals: Primary objective • To assess the efficacy and safety of AZVUDINE (FNC) in relation to placebo, in patients infected w...

Aug 12th, 2022 - Background: Irinotecan is a prodrug of an inhibitor of topoisomerase 1 (active metabolite is SN-38) with known activity in sarcomas, however it has limitations including suboptimal bioavailability and systemic side effects including severe diarrhe...

Aug 10th, 2022 - The efficacy of first-generation BTKi ibrutinib in the treatment of B-cell lymphoma is reasonable, but the kinase selectivity is poor and the off-target effect is increased. It is associated with non-BTK-related adverse reactions such as bleeding,...

Aug 9th, 2022 - The Irritable Bowel Syndrome (IBS) is defined by the association between abdominal pain, bowel dysfunction for longer or shorter periods of time, but in any case, recurring. The absence of well-defined pathophysiological marker, requires a clinica...

Aug 12th, 2022 - To err is human, and therefore also part of being a doctor. At the 28th Further Education Week for Practical Dermatology and Venereology, held last month in Munich, Peter Elsner, MD, former director of the department of dermatology at University H...

Aug 5th, 2022 - The US Food and Drug Administration (FDA) has approved trastuzumab deruxtecan (Enhertu) for the treatment of patients with unresectable or metastatic HER2-low breast cancer. AstraZeneca's and Daiichi Sankyo's IV infusion is the first therapy appro...

Jul 30th, 2022 - Marita Kametas, MSN, FNP-BC, CMSRN, COCN The study by El-Sahy and colleagues highlights the novel role of fecal microbiota transplant (FMT) in the treatment of irritable bowel syndrome (IBS). The safety and efficacy of this treatment was durable a.

Jul 29th, 2022 - No one studying polio knew more than Albert Sabin, the Polish-American scientist whose vaccine against the crippling disease has been used worldwide since 1959. Sabin's oral vaccine provides lifelong immunity. It has one drawback, which Sabin, who...

Jul 27th, 2022 - Key clinical point: Patients with diarrhea -predominant irritable bowel syndrome (IBS-D) vs healthy controls had lower serum zinc levels and poor scores for the quality of life (QoL) and physical and psychological health, and higher scores for dep.