ALLMedicine™ Hepatitis Center

Dec 3rd, 2021 - The association of previous hepatitis B virus (HBV) exposure [hepatitis B surface antigen (HBsAg) negative, hepatitis B core antibody (anti-HBc/HBcAb) positive] with disease severity and decision on treatment option in primary immune thrombocytope...

Dec 3rd, 2021 - In solid organ transplant (SOT) recipients, viral infections are associated with direct morbidity and mortality and may influence long-term allograft outcomes. Prevention of viral infections by vaccination, antiviral prophylaxis, and behavioral me...

Dec 3rd, 2021 - Immune regulation is important for carcinogenesis; however, the cancer risk profiles associated with immune-mediated diseases need further characterization. To assess the prospective association of 48 immune-mediated diseases with the risk of tota...

Dec 3rd, 2021 - This study aims to explore the relationship between chronic hepatitis B virus (HBV) infection and the risk of gastrointestinal (GI) cancers including liver, gastric, gallbladder or extrahepatic bile duct, pancreatic, small intestine, esophageal, a...

Dec 3rd, 2021 - The aim of this study was to provide recommendations for reducing the impact of hepatitis B infection on patients with chronic hepatitis B by describing their experiences during the diagnosis process. We conducted face-to-face interviews with 50 h...

Aug 1st, 2021 - Diagnosis of chronic hepatitis B virus (HBV) infection, initial staging of infection and monitoring of treated and untreated patients are mainly based on clinical, biological and imaging criteria allowing a complete non-invasive management for the...

Aug 1st, 2021 - Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. Clinical care for patients with HCV-related liver disease has advanced considerably with developments in screening, diagnostic procedures to evaluate liver fibrosis and i...

Aug 1st, 2021 - Autoimmune hepatitis (AIH) is a liver disease characterised by necrotico-inflammatory lesions of hepatocytes, the presence of specific autoantibodies and response to corticosteroid treatment. AIH must be considered in any patient with acute or chr...

Jul 9th, 2021 - To provide evidence-based recommendations and expert guidance for the management of systemic polyarteritis nodosa (PAN). Twenty-one clinical questions regarding diagnostic testing, treatment, and management were developed in the population, interv...

Jul 9th, 2021 - To provide evidence-based recommendations and expert guidance for the management of systemic polyarteritis nodosa (PAN). Twenty-one clinical questions regarding diagnostic testing, treatment, and management were developed in the population, interv...

Dec 3rd, 2021 - PRIMARY OBJECTIVE: I. Determine objective response rate (ORR) of durvalumab (D) and D + tremelimumab (T) after radiation therapy (RT) in advanced hepatocellular carcinoma (HCC) patients with progression on prior PD-1 immune checkpoint inhibitor. S...

Dec 3rd, 2021 - Background: Primary liver cancer (PLC) is the 2nd most common cause of cancer-related death worldwide and the one cancer with the fastest rising incidence and mortality in the U.S. PLC consists of two main histological subtypes, i.e., hepatocellul...

Dec 1st, 2021 - This is a randomized, open label, multicenter Phase 2 study investigating the safety and antiviral activity of AB-729 in combination with ongoing NA therapy and short courses of Peg-IFNα-2a in subjects with CHB.

Nov 30th, 2021 - This protocol describes the screening process used by the National Institute on Drug Abuse (NIDA IRP) to assess potential research participants' eligibility for entering protocols of the NIDA/IRP. Through its clinical research protocols, the IRP a...

Nov 29th, 2021 - The primary objective of this post-marketing surveillance study is to collect and assess data related to the safety and effectiveness of Harvoni® (ledipasvir/sofosbuvir (LDV/SOF)) treatment regimen, per the approved Korea prescribing information f...

Dec 2nd, 2021 - The FDA approved the first three-antigen hepatitis B vaccine (PreHevbrio) to prevent infection from all known subtypes in adults, VBI Vaccines announced on Wednesday. Approval for the recombinant vaccine -- which contains the S, pre-S1, and pre-S2...

Nov 17th, 2021 - Although the risk for liver cancer diminishes for patients with hepatitis C virus (HCV) infections for whom virus is eliminated with direct-acting antiviral (DAA) drugs, these patients are not out of the woods, and those who do not have a sustaine...

Nov 16th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Vaccination against SARS-CoV-2 infection can protect patients with liver cirrhosis from decompensation, hospitalization, and death, but getting th...

Nov 16th, 2021 - NEW YORK (Reuters Health) - Heart-transplant recipients with the lowest medical urgency receive hearts from donors with an increased number of comorbidities, including hepatitis C and diabetes, compared with higher-urgency patients, according to n...

Nov 16th, 2021 - NEW YORK (Reuters Health) - Over the past two decades, the need for liver transplant (LT) in older adults has risen sharply, due to rising rates of nonalcoholic steatohepatitis (NASH), and the outcomes of LT in these patients has been improving, a...