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About 780 results

ALLMedicine™ Opioids Center

Research & Reviews  228 results

Variation in opioid prescribing patterns after abdominal transplant surgery.
https://doi.org/10.1111/ctr.14439
Clinical Transplantation; Sussman J, Calderon E et. al.

Jul 24th, 2021 - Opioids are associated with negative transplant outcomes. We sought to identify patient and center effects on over-prescribing of opioids (> 200 OME (oral morphine equivalents)). Clinical and opioid prescription data (2014-2017) were collected fro...

"It's Crazy What Meth Can Help You Do": Lay Beliefs, Practices, and Experiences of Usin...
https://doi.org/10.1080/10826084.2021.1949612
Substance Use & misUse; Silverstein SM, Daniulaityte R et. al.

Jul 20th, 2021 - Across the U.S., methamphetamine use is expanding among people who use illicit opioids (PWUIO). Motives for methamphetamine use must be contextualized within the experiences of PWUIO, who may use methamphetamine not only to achieve euphoria, but a...

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction bet...
https://doi.org/10.1038/s41431-021-00920-y 10.1038/sj.clpt.6100507 10.1038/s41431-018-0205-4 10.1038/clpt.2012.96 10.1097/FPC.0b013e32832e0eac 10.1097/FPC.0000000000000057 10.1097/FPC.0000000000000351 10.1002/cpt.690 10.1007/s00228-006-0250-8 10.1007/s40262-019-00783-z 10.1038/clpt.1990.212 10.1007/BF00280101 10.1007/s002280050200 10.1016/S0304-3959(98)00021-9 10.1097/FTD.0b013e3182272b10 10.1093/bja/aef284 10.1371/journal.pone.0070073 10.1038/tpj.2015.3 10.1038/clpt.2011.280 10.1016/S0140-6736(06)69255-6 10.1038/clpt.2008.157 10.1056/NEJMc0904266 10.1542/peds.2011-2538 10.1097/00007691-199710000-00011 10.1056/NEJMoa041888 10.1016/S0009-9236(96)90211-8 10.1007/s00228-005-0920-y 10.1111/j.1365-2710.2010.01203.x 10.1016/S0304-3959(03)00212-4 10.1213/ane.0b013e31817b796e 10.1542/peds.2014-2673 10.1111/j.1399-6576.2009.02104.x 10.1002/cpt.771 10.1371/journal.pone.0060239 10.1007/s00228-011-1093-5 10.1097/FTD.0b013e318288f158 10.1111/j.1476-5381.2010.00709.x 10.1111/j.1742-7843.2009.00378.x 10.1097/01.jcp.0000085421.74359.60 10.1038/nrd3921 10.1371/journal.pmed.0040209 10.1002/cpt.1049 10.1038/clpt.2013.254 10.1002/cpt.762
European Journal of Human Genetics : EJHG; Matic M, Nijenhuis M et. al.

Jul 17th, 2021 - The current Dutch Pharmacogenetics Working Group (DPWG) guideline, describes the gene-drug interaction between CYP2D6 and the opioids codeine, tramadol and oxycodone. CYP2D6 genotype is translated into normal metaboliser (NM), intermediate metabol...

Postdischarge Nonsteroidal Anti-Inflammatory Drugs Are not Associated with Risk of Hema...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272604
Annals of Surgical Oncology; Pawloski KR, Matar R et. al.

Jul 12th, 2021 - Nonsteroidal anti-inflammatory drugs (NSAIDs) are increasingly used in ambulatory breast surgery. The risk of hematoma associated with intraoperative ketorolac is low, but whether concomitant routine discharge with NSAIDs increases the risk of hem...

Enhanced Recovery After Surgery Patients are Prescribed Fewer Opioids at Discharge: A P...
https://doi.org/10.1097/SLA.0000000000005042
Annals of Surgery; Maurer LR, Moheb ME et. al.

Jul 6th, 2021 - We aimed to compare discharge opioid prescriptions pre- and post-Enhanced Recovery After Surgery (ERAS) implementation. ERAS programs decrease inpatient opioid use, but their relationship with post-discharge opioids remains unclear. All patients u...

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Drugs  26 results see all →

Clinicaltrials.gov  29 results

Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
https://clinicaltrials.gov/ct2/show/NCT02570503

Apr 24th, 2020 - Data Collection: Data will be collected from the patient's medical record after discharge Variables include: Age Sex BMI UPAT score (Universal Pain Assessment Tool)- this is assessed hourly postoperatively by nursing staff on Orthopedics Unit Pati...

Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)
https://clinicaltrials.gov/ct2/show/NCT03726268

Apr 21st, 2020 - This protocol will test the innovative, paradigm-shifting hypothesis that anesthesia for outpatient surgery with long-duration opioids (methadone), compared with conventional short-duration opioids, achieves better analgesia, with similar or dimin...

Pilocarpine in Treating Patients With Dry Mouth Caused by Opioids
https://clinicaltrials.gov/ct2/show/NCT00003686

Apr 3rd, 2020 - OBJECTIVES: I. Evaluate the effectiveness of daily oral pilocarpine versus placebo in relieving dry mouth due to the ongoing use of an opioid for cancer related pain at 2 weeks by comparing proportion of patients with at least one response during ...

Safe Return and Disposal of Unused Opioids
https://clinicaltrials.gov/ct2/show/NCT03352479

Mar 31st, 2020 - Participants identified by the PI and participating research staff/coordinators that will receive opioids following discharge will be approached. The participant information sheet will be provided to the parents/legal guardian and explained. The c...

Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function
https://clinicaltrials.gov/ct2/show/NCT02469077

Dec 10th, 2019 - This project will determine whether enhancing endogenous opioids (via aerobic exercise training) permits achieving desired levels of analgesia with lower dosages of opioid analgesics, and fewer side effects and abuse-relevant drug effects. This 4 ...

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News  29 results

Suggestions During Anesthesia May Reduce Pain, Opioid Use After Surgery
https://www.medscape.com/viewarticle/942696

Dec 16th, 2020 - (Reuters Health) - Patients who heard therapeutic suggestions during surgery requiring general anesthesia experienced significantly less pain and used less opioids after surgery, a clinical trial found. Researchers randomly assigned 385 patients u...

New York charges Endo with insurance fraud over opioid claims
https://www.reuters.com/article/us-endo-new-york-opioids-fraud/new-york-charges-endo-with-insurance-fraud-over-opioid-claims-idUSKBN23H35I

Jun 10th, 2020 - NEW YORK (Reuters) - New York state filed civil charges on Wednesday accusing Endo International Plc of insurance fraud for misrepresenting the safety and efficacy of its opioid drugs, adding fuel to the nation’s opioid crisis. Governor Andrew Cuo...

Anesthesia Technique Flops in Large Breast Cancer Trial
https://www.medpagetoday.com/hematologyoncology/breastcancer/82905

Oct 23rd, 2019 - Despite expectations to the contrary, regional anesthesia-analgesia with paravertebral blocks and propofol during breast cancer surgery did not lower the risk of disease recurrence or incidence of persistent pain compared with general anesthesia w...

Fast Five Quiz: Drug Overdoses
https://reference.medscape.com/viewarticle/920159

Oct 23rd, 2019 - Drug overdose remains a significant concern worldwide, with nearly half a million deaths annually. In the United States, drug overdoses are the leading cause of death for adults younger than 55 years. Drug-related deaths now outnumber those attrib...

Opioid use booming as tramadol crisis emerges in Africa - U.N. drug report
https://www.reuters.com/article/us-un-drugs/opioid-use-booming-as-tramadol-crisis-emerges-in-africa-u-n-drug-report-idUSKCN1TQ2ZG

Jun 25th, 2019 - VIENNA (Reuters) - Synthetic opioid use is booming, the United Nations said on Wednesday in a worldwide drug report that showed deaths in the United States from overdoses still rising and a “crisis” of tramadol use emerging in parts of Africa. The...

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