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About 1,864 results

ALLMedicine™ Opioids Center

Research & Reviews  821 results

An Investigation into Proteomic Constituents of Cerebrospinal Fluid in Patients with Ch...
https://doi.org/10.1007/s11481-020-09970-3
Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology; Royds J, Cassidy H et. al.

Nov 21st, 2020 - The pharmacodynamics of opioids for chronic peripheral neuropathic pain are complex and likely extend beyond classical opioid receptor theory. Preclinical evidence of opioid modulation of central immune signalling has not been identified in vivo i...

Evaluating Pain, Opioids, and Delirium in Critically Ill Older Adults.
https://doi.org/10.1177/1054773820973123
Clinical Nursing Research; Pavone KJ, Jablonski J et. al.

Nov 20th, 2020 - Untreated pain and pain management with opioids are independent precipitating factors for delirium. This retrospective study evaluated the relationships among pain severity, its management with opioids, and the onset of delirium in older adult pat...

A review of the existing literature on buprenorphine pharmacogenomics.
https://doi.org/10.1038/s41397-020-00198-1
The Pharmacogenomics Journal; Meaden CW, Mozeika A et. al.

Nov 6th, 2020 - Buprenorphine is an effective treatment for opioid dependence; however, it demonstrates individual variability in efficacy. Pharmacogenomics may explain this drug response variability and could allow for tailored therapy on an individual basis. Th...

Use and Perceptions of Opioids versus Marijuana among People Living with HIV.
https://doi.org/10.5993/AJHB.44.6.6
American Journal of Health Behavior; Potts JM, Getachew B et. al.

Oct 21st, 2020 - Objectives: In this study, we examined use of and interest in using opioids and marijuana, particularly in relation to use motives and perceived barriers to use, among people living with HIV (PLWH). Methods: We analyzed online survey data from 304...

Alternatives to Opioid Education and a Prescription Drug Monitoring Program Cumulativel...
https://doi.org/10.1093/pm/pnaa278
Pain Medicine (Malden, Mass.); Sigal A, Shah A et. al.

Oct 17th, 2020 - Deaths have increased, and prescription medications are involved in a significant percentage of deaths. Emergency department (ED) changes to managing acute pain and prescription drug monitoring programs (PDMPs) can impact the potential for abuse. ...

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Guidelines  4 results

Drug Overdose Deaths | Drug Overdose | CDC Injury Center
https://www.cdc.gov/drugoverdose/data/statedeaths.html

Jun 26th, 2019 - 70,237 drug overdose deaths occurred in the United States in 2017. The age-adjusted rate of overdose deaths increased significantly by 9.6% from 2016 (19.8 per 100,000) to 2017 (21.7 per 100,000). Opioids—mainly synthetic opioids (other than metha...

Binge Drinking and Prescription Opioid Misuse in the U.S., 2012–2014
https://www.ajpmonline.org/article/S0749-3797(19)30157-6/fulltext
American Journal of Preventive Medicine; Esser,M,et al

Jun 10th, 2019 - Introduction Prescription opioids were responsible for approximately 17,000 deaths in the U.S. in 2016. One in five prescription opioid deaths also involve alcohol. Drinkers who misuse prescription opioids (i.e., use without a prescription or use ...

Fentanyl and Other Synthetic Opioids Drug Overdose Deaths
https://www.drugabuse.gov/related-topics/trends-statistics/infographics/fentanyl-other-synthetic-opioids-drug-overdose-deaths

Apr 30th, 2018 - In 2016, synthetic opioids (primarily illegal fentanyl) passed prescription opioids as the most common drugs involved in overdose deaths in the United States.

Modeling dynamics of fatal opioid overdose by state and across time
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516293/
Preventive Medicine Reports; Lyle Cooper R, Thompson J et. al.

Opioid overdose fatalities include deaths from natural opioids (morphine and codeine), semi-synthetic opioids (oxycodone, hydrocodone), synthetic opioids (prescription and illicit fentanyl, tramadol), methadone, and heroin. From 1999 to 2017, ther...

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Drugs  43 results see all →

Clinicaltrials.gov  929 results

An Investigation into Proteomic Constituents of Cerebrospinal Fluid in Patients with Ch...
https://doi.org/10.1007/s11481-020-09970-3
Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology; Royds J, Cassidy H et. al.

Nov 21st, 2020 - The pharmacodynamics of opioids for chronic peripheral neuropathic pain are complex and likely extend beyond classical opioid receptor theory. Preclinical evidence of opioid modulation of central immune signalling has not been identified in vivo i...

Evaluating Pain, Opioids, and Delirium in Critically Ill Older Adults.
https://doi.org/10.1177/1054773820973123
Clinical Nursing Research; Pavone KJ, Jablonski J et. al.

Nov 20th, 2020 - Untreated pain and pain management with opioids are independent precipitating factors for delirium. This retrospective study evaluated the relationships among pain severity, its management with opioids, and the onset of delirium in older adult pat...

A review of the existing literature on buprenorphine pharmacogenomics.
https://doi.org/10.1038/s41397-020-00198-1
The Pharmacogenomics Journal; Meaden CW, Mozeika A et. al.

Nov 6th, 2020 - Buprenorphine is an effective treatment for opioid dependence; however, it demonstrates individual variability in efficacy. Pharmacogenomics may explain this drug response variability and could allow for tailored therapy on an individual basis. Th...

Amitiza - lubiprostone capsule, gelatin coated-Takeda Pharmaceuticals America, Inc.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d474ac6a-444d-4aa6-9986-24be6fcf811d

Oct 29th, 2020 - Amitiza is a chloride channel activator indicated for the treatment of: chronic idiopathic constipation (CIC) in adults. (1.1) opioid-induced constipation (OIC) in adult patients with chronic, non-cancer pain, including patients with chronic pain ...

Methadone hydrochloride - methadone hydrochloride tablet-Quality Care Products, LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4b340760-f05b-4af6-892a-fca8cd948fd6

Oct 25th, 2020 - Methadone hydrochloride tablets, USP are indicated for the: Management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Limitations of Use Because of t...

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News  65 results

New York charges Endo with insurance fraud over opioid claims
https://www.reuters.com/article/us-endo-new-york-opioids-fraud/new-york-charges-endo-with-insurance-fraud-over-opioid-claims-idUSKBN23H35I

Jun 10th, 2020 - NEW YORK (Reuters) - New York state filed civil charges on Wednesday accusing Endo International Plc of insurance fraud for misrepresenting the safety and efficacy of its opioid drugs, adding fuel to the nation’s opioid crisis. Governor Andrew Cuo...

Anesthesia Technique Flops in Large Breast Cancer Trial
https://www.medpagetoday.com/hematologyoncology/breastcancer/82905

Oct 23rd, 2019 - Despite expectations to the contrary, regional anesthesia-analgesia with paravertebral blocks and propofol during breast cancer surgery did not lower the risk of disease recurrence or incidence of persistent pain compared with general anesthesia w...

Fast Five Quiz: Drug Overdoses
https://reference.medscape.com/viewarticle/920159

Oct 22nd, 2019 - Drug overdose remains a significant concern worldwide, with nearly half a million deaths annually. In the United States, drug overdoses are the leading cause of death for adults younger than 55 years. Drug-related deaths now outnumber those attrib...

Drug Overdose Deaths | Drug Overdose | CDC Injury Center
https://www.cdc.gov/drugoverdose/data/statedeaths.html

Jun 26th, 2019 - 70,237 drug overdose deaths occurred in the United States in 2017. The age-adjusted rate of overdose deaths increased significantly by 9.6% from 2016 (19.8 per 100,000) to 2017 (21.7 per 100,000). Opioids—mainly synthetic opioids (other than metha...

Opioid use booming as tramadol crisis emerges in Africa - U.N. drug report
https://www.reuters.com/article/us-un-drugs/opioid-use-booming-as-tramadol-crisis-emerges-in-africa-u-n-drug-report-idUSKCN1TQ2ZG

Jun 25th, 2019 - VIENNA (Reuters) - Synthetic opioid use is booming, the United Nations said on Wednesday in a worldwide drug report that showed deaths in the United States from overdoses still rising and a “crisis” of tramadol use emerging in parts of Africa. The...

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Patient Education  2 results see all →