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About 135,408 results

ALLMedicine™ Schizophrenia Center

Research & Reviews  65,329 results

Association between genetic and socioenvironmental risk for schizophrenia during upbrin...
https://doi.org/10.1017/S0033291720003347
Psychological Medicine; Newbury JB, Arseneault L et. al.

Sep 25th, 2020 - Associations of socioenvironmental features like urbanicity and neighborhood deprivation with psychosis are well-established. An enduring question, however, is whether these associations are causal. Genetic confounding could occur due to downward ...

Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression ...
https://doi.org/10.1093/hmg/ddaa213
Human Molecular Genetics; Cosgrove D, Whitton L et. al.

Sep 25th, 2020 - Myocyte enhancer factor 2 C (MEF2C) is an important transcription factor during neurodevelopment. Mutation or deletion of MEF2C causes intellectual disability (ID) and common variants within MEF2C are associated with cognitive function and schizop...

Effects of Antipsychotic Drugs: Cross Talk Between the Nervous and Innate Immune System.
https://doi.org/10.1007/s40263-020-00765-x
CNS Drugs; Dinesh AA, Islam J et. al.

Sep 25th, 2020 - Converging lines of evidence suggest that activation of microglia (innate immune cells in the central nervous system [CNS]) is present in a subset of patients with schizophrenia. The extent to which antipsychotic drug treatment contributes to or c...

Oral health perception and plight of patients of Schizophrenia.
https://doi.org/10.1111/idh.12467
International Journal of Dental Hygiene; Agarwal D, Kumar A et. al.

Sep 24th, 2020 - To assess the oral health status, perception and dental treatment needs in patients of schizophrenia in the hospital set up in Rohtak district, Haryana. Across sectional study was conducted to assess the oral health in patients of schizophrenia at...

Liver enzyme CYP2D6 gene and tardive dyskinesia.
https://doi.org/10.2217/pgs-2020-0065
Pharmacogenomics Lu JY, Tiwari AK et. al.

Sep 24th, 2020 - Background: Tardive dyskinesia (TD) is an iatrogenic involuntary movement disorder occurring after extended antipsychotic use with an unclear pathogenesis. CYP2D6 is a liver enzyme involved in antipsychotic metabolism and a well-studied gene candi...

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Guidelines  41 results

CAPLYTA® (lumateperone) | Now Approved | caplyta.com‎
https://www.caplyta.com/‎

Jan 13th, 2020 - Learn about a new treatment. See full safety information, PI, and boxed warning. Get information about this orally administered capsule. Press Release. Prescribing Information. MOA. Important Safety Info. Dosing & Administration.

Cannabidiol as a potential treatment for psychosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843725/
Therapeutic Advances in Psychopharmacology; Davies C,et al

Nov 7th, 2019 - Psychotic disorders such as schizophrenia are heterogeneous and often debilitating conditions that contribute substantially to the global burden of disease. The introduction of dopamine D2 receptor antagonists in the 1950s revolutionised the treat...

U.S. FDA Approves SECUADO® (asenapine) Transdermal System, the First-and-Only Transdermal Patch for the Treatment of Adults with Schizophrenia
http://www.noven.com/PR101519.php

Oct 14th, 2019 - Noven Pharmaceuticals, Inc., a wholly-owned subsidiary of Hisamitsu Pharmaceutical Co., Inc., today announced the U.S. Food and Drug Administration (FDA) has approved SECUADO® (asenapine) transdermal system, the first-and-only transdermal patch fo...

HIV, schizophrenia, and all-cause mortality
https://www.sciencedirect.com/science/article/abs/pii/S0920996419301537?via%3Dihub
Schizophrenia Research;

Jun 26th, 2019 - Schizophrenia is a severe mental illness with important implications for morbidity and mortality. This population-based cohort study examined the impact of schizophrenia diagnoses on all-cause mortality among a sample of people living with HIV (PL...

Switching patients with schizophrenia from paliperidone palmitate to aripiprazole lauroxil: A 6-month, prospective, open-label study
https://www.sciencedirect.com/science/article/pii/S0920996419300416?via%3Dihub
Miller,B.,et al

Feb 6th, 2019 - We assessed the effectiveness of switching from paliperidone palmitate (PP) or risperidone long-acting injection (RLAI) to aripiprazole lauroxil (AL). Prospective, 6-month study in patients with schizophrenia with residual symptoms or intolerance ...

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Drugs  1,503 results see all →

Clinicaltrials.gov  67,127 results

Association between genetic and socioenvironmental risk for schizophrenia during upbrin...
https://doi.org/10.1017/S0033291720003347
Psychological Medicine; Newbury JB, Arseneault L et. al.

Sep 25th, 2020 - Associations of socioenvironmental features like urbanicity and neighborhood deprivation with psychosis are well-established. An enduring question, however, is whether these associations are causal. Genetic confounding could occur due to downward ...

Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression ...
https://doi.org/10.1093/hmg/ddaa213
Human Molecular Genetics; Cosgrove D, Whitton L et. al.

Sep 25th, 2020 - Myocyte enhancer factor 2 C (MEF2C) is an important transcription factor during neurodevelopment. Mutation or deletion of MEF2C causes intellectual disability (ID) and common variants within MEF2C are associated with cognitive function and schizop...

Effects of Antipsychotic Drugs: Cross Talk Between the Nervous and Innate Immune System.
https://doi.org/10.1007/s40263-020-00765-x
CNS Drugs; Dinesh AA, Islam J et. al.

Sep 25th, 2020 - Converging lines of evidence suggest that activation of microglia (innate immune cells in the central nervous system [CNS]) is present in a subset of patients with schizophrenia. The extent to which antipsychotic drug treatment contributes to or c...

Oral health perception and plight of patients of Schizophrenia.
https://doi.org/10.1111/idh.12467
International Journal of Dental Hygiene; Agarwal D, Kumar A et. al.

Sep 24th, 2020 - To assess the oral health status, perception and dental treatment needs in patients of schizophrenia in the hospital set up in Rohtak district, Haryana. Across sectional study was conducted to assess the oral health in patients of schizophrenia at...

Liver enzyme CYP2D6 gene and tardive dyskinesia.
https://doi.org/10.2217/pgs-2020-0065
Pharmacogenomics Lu JY, Tiwari AK et. al.

Sep 24th, 2020 - Background: Tardive dyskinesia (TD) is an iatrogenic involuntary movement disorder occurring after extended antipsychotic use with an unclear pathogenesis. CYP2D6 is a liver enzyme involved in antipsychotic metabolism and a well-studied gene candi...

see more →

News  1,371 results

Minerva's schizophrenia drug misses main goal in study; shares tumble
https://www.reuters.com/article/us-minerva-study/minervas-schizophrenia-drug-misses-main-goal-in-study-shares-tumble-idUSKBN23521L

May 29th, 2020 - (Reuters) - Drug developer Minerva Neurosciences Inc said on Friday its experimental drug for schizophrenia did not meet the main goal of a late-stage study, sending its shares down nearly 66% in early trade. The drug, roluperidone, did not show s...

Is psychosis toxic to the brain?
https://www.mdedge.com/psychiatry/article/219773/schizophrenia-other-psychotic-disorders/psychosis-toxic-brain?channel=133
Gerald Martone, MS, MSN, PMHNP-BC

Mar 31st, 2020 - Schizophrenia has been described as the “worst disease” to afflict mankind. 1 It causes psychosis, which is an abnormal state of mind marked by hyperarousal, overactivation of brain circuits, and emotional distress.

Paradise lost: Life, liberty, and the pursuit of happiness among psychiatric patients
https://www.mdedge.com/psychiatry/article/217949/paradise-lost-life-liberty-and-pursuit-happiness-among-psychiatric/page/0/1?channel=41022

Mar 2nd, 2020 - Happiness. I often wonder if most Americans these days are pursuing pleasure rather than happiness, seeking the momentary thrill and gratification instead of long-lasting happiness and joy.

Severe infection tied to substance-induced psychosis, conversion to schizophrenia
https://www.mdedge.com/psychiatry/article/217686/schizophrenia-other-psychotic-disorders/severe-infection-tied-substance/page/0/1?channel=293

Feb 22nd, 2020 - Interpret with caution Commenting on the study, Ole Köhler-Forsberg, MD, from the Psychosis Research Unit, Aarhus University Hospital, Denmark, said in an interview that the findings support a potential immunologic link to schizophrenia. “However,.

TNF-alpha, oxidative stress disturbance may play role in schizophrenia pathophysiology
https://www.mdedge.com/psychiatry/article/217681/schizophrenia-other-psychotic-disorders/tnf-alpha-oxidative-stress?channel=39313
Lucas Franki

Feb 22nd, 2020 - Disturbance of tumor necrosis factor (TNF)–alpha and oxidative stress status may be involved in the pathophysiology of schizophrenia, new study results suggest. In a study published in Psychoneuroendocrinology, the investigators collected blood sa.

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Patient Education  37 results see all →