ALLMedicine™ Addiction Center

Mar 20th, 2023 - Proteasome inhibitors are in use in treating certain types of cancers. These drugs inhibit the catalytic activity of the 20S proteasome, shared by all the different proteasome complexes. Inhibitors of the 26S-associated deubiquitinating activity e...

Mar 19th, 2023 - Childhood maltreatment, cognitive emotion regulation strategies (CERSs), and depression can be important in adolescents' Internet addiction. The current study aims to investigate the direct effect of childhood maltreatment on Internet addiction an...

Mar 19th, 2023 - Reconsolidation results in the restabilisation, and thus persistence, of a memory made labile by retrieval, and interfering with this process is thought to enable modification or weakening of the original trace. As such, reconsolidation-blockade h...

Mar 19th, 2023 - A link between gut dysbiosis and the pathogenesis of brain disorders has been identified. A role for gut bacteria in drug reward and addiction has been suggested but very few studies have investigated their impact on brain and behavioral responses...

Mar 19th, 2023 - One-third of cancers activate endogenous synthesis of serine/glycine, and can become addicted to this pathway to sustain proliferation and survival. Mechanisms driving this metabolic rewiring remain largely unknown. NKX2-1 overexpressing and NKX2-...

Jul 25th, 2022 - Cannabis potency, defined as the concentration of Δ9-tetrahydrocannabinol (THC), has increased internationally, which could increase the risk of adverse health outcomes for cannabis users. We present, to our knowledge, the first systematic review ...

Dec 16th, 2021 - The ASAM Clinical Practice Guideline on Alcohol Withdrawal Management RELEASE DATE: May 2020 PRIOR VERSION: 2004 American Society of Addiction Medicine guideline on management of alcohol withdrawal delirium DEVELOPER: American Society of Addiction...

Jan 25th, 2021 - Opioid-related morbidity and mortality have risen in many settings globally. It is critical that practitioners who work with adolescents and young adults (AYAs) provide timely, evidence-based treatment for opioid use disorder (OUD). Such treatment...

Sep 11th, 2020 - : The American Society of Addiction Medicine (ASAM) Clinical Practice Guideline on Alcohol Withdrawal Management provides guidance on the identification and management of alcohol withdrawal in adults with varying degrees of syndrome severity. The ...

Mar 27th, 2020 - : A Focused Update of the ASAM National Practice Guideline for the Treatment of Opioid Use Disorder is published in the current issue of the Journal of Addiction Medicine. The focused update included a search of Medline's PubMed database from Janu...

Mar 10th, 2023 - This protocol describes the screening process used by the National Institute on Drug Abuse (NIDA IRP) to assess potential research participants' eligibility for entering protocols of the NIDA/IRP. Through its clinical research protocols, the IRP a...

Mar 10th, 2023 - Methamphetamine misuse has become a growing concern in Alberta, creating a burden on the health care system. Further, individuals who use methamphetamine in Alberta exhibit significant difficulty remaining in treatment. These troubling patterns ne...

Mar 10th, 2023 - INTRODUCTION AND AIM Diabetes Mellitus (DM) is a common endocrine disease in the world. Colon polyps and colorectal cancers are reported more in DM patients. Therefore diabetic patients are recommended to have colonoscopy frequently. The aim of th...

Mar 10th, 2023 - Phase B Background. The reasons for initiation and continuation of use of illicit substances are multifactorial; however, some individuals appear resistant to both. One set of determinants lies in the environment. In ongoing studies, we are examin...

Mar 10th, 2023 - Opioid use is rising at unprecedented levels and has reached epidemic proportions in some areas of the country, particularly rural areas. Although research on the detrimental effects of opioid use on parenting and children is relatively new, it is...

Mar 20th, 2023 - Note that some links may require subscriptions. A Washington Post analysis suggests long COVID symptoms have become less common since the Omicron variant. Military pilots have higher rates of cancer, as do aircraft ground crews, a Pentagon study f...

Mar 15th, 2023 - Psychological studies may be skewed due to the fact that participants are more likely to have personality disorders than the general population. (PLOS One) Pregnant and postpartum women with schizophrenia had as much as a threefold higher risk of ...

Feb 20th, 2023 - Adding the statin simvastatin into the mix was no help for patients with treatment-resistant depression, according to a randomized clinical trial. Compared with placebo, patients who added 20 mg/day of simvastatin on top of standard of care didn't...

Feb 13th, 2023 - Buprenorphine, rather than a full agonist opioid, should be used for patients taking daily opioids for chronic pain, given its lower risk for overdose or misuse, new guidelines from the Department of Veterans Affairs (VA) and Department of Defense...

Feb 10th, 2023 - In 2016, when Erin Schanning lost her brother Ethan to an overdose, she wanted to know what could have been done to have helped him. Ethan, who had struggled with opioids since getting a prescription for the drugs after a dental procedure in middl.