About 90,883 results

ALLMedicine™ Schizophrenia Center

Research & Reviews  29,519 results

Abnormal Structural Network Communication Reflects Cognitive Deficits in Schizophrenia.
Brain Topography; Zorlu N, Bayrakçı A et. al.

Mar 28th, 2023 - Schizophrenia has long been thought to be a disconnection syndrome and several previous studies have reported widespread abnormalities in white matter tracts in individuals with schizophrenia. Furthermore, reductions in structural connectivity may...

Interhemispheric differences of pyramidal cells in the primary motor cortices of schizo...
Cerebral Cortex (New York, N.Y. : 1991); Szocsics P, Papp P et. al.

Mar 27th, 2023 - Motor disturbances are observed in schizophrenia patients, but the neuroanatomical background is unknown. Our aim was to investigate the pyramidal cells of the primary motor cortex (BA 4) in both hemispheres of postmortem control and schizophrenia...

Early trajectory of clinical global impression as a transdiagnostic predictor of psychi...
The Lancet. Psychiatry; Taquet M, Griffiths K et. al.

Mar 27th, 2023 - Identifying patients most at risk of psychiatric hospitalisation is crucial to improving service provision and patient outcomes. Existing predictors focus on specific clinical scenarios and are not validated with real-world data, limiting their tr...

DNA topoisomerase Top3β is impacted by early life stress in the developing female and m...
Brain Research; Cuarenta A, Kigar SL et. al.

Mar 27th, 2023 - DNA topoisomerases are essential for preserving genomic integrity. DNA topoisomerases induce breakage of DNA to facilitate replication and transcription by relaxing DNA and relieving supercoiling. Aberrant expression and deletions of topoisomerase...

Medication adherence and cognitive performance in schizophrenia-spectrum and bipolar di...
Translational Psychiatry; Senner F, Hiendl L et. al.

Mar 26th, 2023 - Existing guidelines recommend psychopharmacological treatment for the management of schizophrenia and bipolar disorder as part of holistic treatment concepts. About half of the patients do not take their medication regularly, although treatment ad...

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Guidelines  11 results

Severe COVID-19 may increase the risk for schizophrenia
PsyPost Manis E.

Oct 18th, 2022 - A new study published in Psychiatry Research suggests that experiencing a serious case of COVID-19 is associated with increased risk of developing schizophrenia. COVID-19 has had massive effects on society and many individuals’ health that will...

The American Psychiatric Association Practice Guideline for the Treatment of Patients W...
The American Journal of Psychiatry; Keepers GA, Fochtmann LJ et. al.

Sep 2nd, 2020 - The American Psychiatric Association Practice Guideline for the Treatment of Patients With Schizophrenia.|2020|Keepers GA,Fochtmann LJ,Anzia JM,Benjamin S,Lyness JM,|methods,methods,methods,classification,therapeutic use,diagnosis,therapy,

Evidence-based guidelines for the pharmacological treatment of schizophrenia: Updated r...
Journal of Psychopharmacology (Oxford, England); Barnes TR, Drake R et. al.

Dec 13th, 2019 - These updated guidelines from the British Association for Psychopharmacology replace the original version published in 2011. They address the scope and targets of pharmacological treatment for schizophrenia. A consensus meeting was held in 2017, i...

EPA guidance on physical activity as a treatment for severe mental illness: a meta-revi...
European Psychiatry : the Journal of the Association of E... Stubbs B, Vancampfort D et. al.

Sep 28th, 2018 - Physical activity (PA) may be therapeutic for people with severe mental illness (SMI) who generally have low PA and experience numerous life style-related medical complications. We conducted a meta-review of PA interventions and their impact on he...

BAP guidelines on the management of weight gain, metabolic disturbances and cardiovascu...
Journal of Psychopharmacology (Oxford, England); Cooper SJ, Reynolds GP et. al.

May 6th, 2016 - Excess deaths from cardiovascular disease are a major contributor to the significant reduction in life expectancy experienced by people with schizophrenia. Important risk factors in this are smoking, alcohol misuse, excessive weight gain and diabe...

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Drugs  1,100 results see all →

Clinicaltrials.gov  3,033 results

Skills Training to Enhance Vocational Outcomes in Veterans With Serious Mental Illness

Mar 23rd, 2023 - Maintenance of employment is dependent upon being able to successfully integrate into one's work setting. This can present a significant challenge to individuals with serious mental illness, as they typically exhibit impairment in their ability to...

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

Mar 20th, 2023 - This is a Phase 3, multicenter, 52-week, outpatient, open-label extension (OLE) study to evaluate the long-term safety and tolerability of adjunctive KarXT in subjects with schizophrenia with an inadequate response to their current antipsychotic t...

Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder

Mar 17th, 2023 - To compare changes in body mass index (BMI) Z-score following treatment with OLZ/SAM vs olanzapine

Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects

Mar 17th, 2023 - To evaluate the long-term safety and tolerability of OLZ/SAM in pediatric subjects with schizophrenia or Bipolar I disorder

VIA Family - Family Based Early Intervention Versus Treatment as Usual

Mar 16th, 2023 - Background: Children born to parents with severe mental illness like schizophrenia, bipolar disorder or major recurrent depression have an increased risk of developing a mental illness themselves during life. These children are also more likely to...

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News  2,644 results

Caplyta Success in Major Depression; Mental Illness and Aging; New PTSD Device OK'd

Mar 29th, 2023 - Once-daily lumateperone (Caplyta, 42 mg) as monotherapy met its primary endpoint in a trial of major depressive disorder or bipolar depression with mixed features, significantly reducing symptoms and severity over 6 weeks versus placebo, said Intr...

Buprenorphine Urine Spiking; More Positive KarXT Data in Schizophrenia; Sad Seattle

Mar 22nd, 2023 - New research finds that patients who spike their urine with buprenorphine to cheat adherence testing are more likely to be positive for non-prescribed opioids, highlighting the need for best practices in this setting. "Spiking suggests that treatm...

Widespread Erosions in Intertriginous Areas
Alejandra Méndez, MPH, Jonathan Webster, MD et. al.

Mar 15th, 2023 - The Diagnosis: Darier Disease A clinical diagnosis of Darier disease was made from the skin findings of pruritic, malodorous, keratotic papules in a seborrheic distribution and pathognomonic nail dystrophy, along with a family history that demonst.

Psych Studies Skewed; Depression Device Gets FDA 'Breakthrough'; Beauty Filters Bad?

Mar 15th, 2023 - Psychological studies may be skewed due to the fact that participants are more likely to have personality disorders than the general population. (PLOS One) Pregnant and postpartum women with schizophrenia had as much as a threefold higher risk of ...

Cognitive remediation training reduces aggression in schizophrenia
Heidi Splete

Mar 9th, 2023 - Cognitive remediation training, with or without social cognitive training, was associated with reduced aggressive behavior in schizophrenia, based on data from 130 individuals. Aggressive behavior, including verbal or physical threats or violent a.

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Patient Education  46 results see all →