ALLMedicine™ Schizophrenia Center

Mar 28th, 2023 - Schizophrenia has long been thought to be a disconnection syndrome and several previous studies have reported widespread abnormalities in white matter tracts in individuals with schizophrenia. Furthermore, reductions in structural connectivity may...

Mar 27th, 2023 - Motor disturbances are observed in schizophrenia patients, but the neuroanatomical background is unknown. Our aim was to investigate the pyramidal cells of the primary motor cortex (BA 4) in both hemispheres of postmortem control and schizophrenia...

Mar 27th, 2023 - Identifying patients most at risk of psychiatric hospitalisation is crucial to improving service provision and patient outcomes. Existing predictors focus on specific clinical scenarios and are not validated with real-world data, limiting their tr...

Mar 27th, 2023 - DNA topoisomerases are essential for preserving genomic integrity. DNA topoisomerases induce breakage of DNA to facilitate replication and transcription by relaxing DNA and relieving supercoiling. Aberrant expression and deletions of topoisomerase...

Mar 26th, 2023 - Existing guidelines recommend psychopharmacological treatment for the management of schizophrenia and bipolar disorder as part of holistic treatment concepts. About half of the patients do not take their medication regularly, although treatment ad...

Oct 18th, 2022 - A new study published in Psychiatry Research suggests that experiencing a serious case of COVID-19 is associated with increased risk of developing schizophrenia. COVID-19 has had massive effects on society and many individuals’ health that will...

Sep 2nd, 2020 - The American Psychiatric Association Practice Guideline for the Treatment of Patients With Schizophrenia.|2020|Keepers GA,Fochtmann LJ,Anzia JM,Benjamin S,Lyness JM,|methods,methods,methods,classification,therapeutic use,diagnosis,therapy,

Dec 13th, 2019 - These updated guidelines from the British Association for Psychopharmacology replace the original version published in 2011. They address the scope and targets of pharmacological treatment for schizophrenia. A consensus meeting was held in 2017, i...

Sep 28th, 2018 - Physical activity (PA) may be therapeutic for people with severe mental illness (SMI) who generally have low PA and experience numerous life style-related medical complications. We conducted a meta-review of PA interventions and their impact on he...

May 6th, 2016 - Excess deaths from cardiovascular disease are a major contributor to the significant reduction in life expectancy experienced by people with schizophrenia. Important risk factors in this are smoking, alcohol misuse, excessive weight gain and diabe...

Mar 23rd, 2023 - Maintenance of employment is dependent upon being able to successfully integrate into one's work setting. This can present a significant challenge to individuals with serious mental illness, as they typically exhibit impairment in their ability to...

Mar 20th, 2023 - This is a Phase 3, multicenter, 52-week, outpatient, open-label extension (OLE) study to evaluate the long-term safety and tolerability of adjunctive KarXT in subjects with schizophrenia with an inadequate response to their current antipsychotic t...

Mar 17th, 2023 - To compare changes in body mass index (BMI) Z-score following treatment with OLZ/SAM vs olanzapine

Mar 17th, 2023 - To evaluate the long-term safety and tolerability of OLZ/SAM in pediatric subjects with schizophrenia or Bipolar I disorder

Mar 16th, 2023 - Background: Children born to parents with severe mental illness like schizophrenia, bipolar disorder or major recurrent depression have an increased risk of developing a mental illness themselves during life. These children are also more likely to...

Mar 29th, 2023 - Once-daily lumateperone (Caplyta, 42 mg) as monotherapy met its primary endpoint in a trial of major depressive disorder or bipolar depression with mixed features, significantly reducing symptoms and severity over 6 weeks versus placebo, said Intr...

Mar 22nd, 2023 - New research finds that patients who spike their urine with buprenorphine to cheat adherence testing are more likely to be positive for non-prescribed opioids, highlighting the need for best practices in this setting. "Spiking suggests that treatm...

Mar 15th, 2023 - The Diagnosis: Darier Disease A clinical diagnosis of Darier disease was made from the skin findings of pruritic, malodorous, keratotic papules in a seborrheic distribution and pathognomonic nail dystrophy, along with a family history that demonst.

Mar 15th, 2023 - Psychological studies may be skewed due to the fact that participants are more likely to have personality disorders than the general population. (PLOS One) Pregnant and postpartum women with schizophrenia had as much as a threefold higher risk of ...

Mar 9th, 2023 - Cognitive remediation training, with or without social cognitive training, was associated with reduced aggressive behavior in schizophrenia, based on data from 130 individuals. Aggressive behavior, including verbal or physical threats or violent a.