ALLMedicine™ Immunodeficiency Center

Aug 1st, 2021 - During the Coronavirus Disease 2019 pandemic, patients with humoral immunodeficiency are at higher risk of developing chronic infection and having negative outcome. Little data are available on therapeutic options for this population. We discuss t...

Aug 1st, 2021 - To characterise the high-risk HPV types associated with cervical precancerous lesions in women living in Yaounde Cameroon, and to determine their distribution with HIV status. Women with abnormal pap smears recorded from February 2015 to May 2019 ...

Jul 31st, 2021 - Immunosuppressive drugs can alleviate debilitating symptoms of autoimmune diseases, but, by the same token, excessive immune suppression can result in an increased risk of infection. Despite the dangers of a compromised immune system, clear defini...

Jul 31st, 2021 - Autoimmune lymphoproliferative syndrome is a primary immunodeficiency caused by variants in FAS-mediated apoptosis related genes and is characterized by lymphadenopathy, splenomegaly and autoimmunity. A total of six different variants in CASP10 ha...

Jul 30th, 2021 - Children with primary immunodeficiency disorders (PID) are more susceptible to developing viral infections and are at a substantially increased risk of developing paralytic poliomyelitis. Such children, if given oral polio vaccines tend to excrete...

Dec 15th, 2020 - La présente directive clinique révisée met à jour les renseignements sur la prestation de soins aux femmes atteintes d'une infection virale chronique devant se soumettre à un test diagnostique fœtal intra-utérin. Femmes atteintes d'une infection v...

Dec 15th, 2020 - This revised guideline provides updated information for the care of women with chronic viral infections who require intrauterine fetal diagnostic testing. Women with chronic viral infections who are pregnant or planning a pregnancy. Non-invasive s...

Aug 17th, 2020 - Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (wit...

Apr 10th, 2020 - "U.S. Medical Eligibility Criteria for Contraceptive Use" (U.S. MEC) 2016 provides evidence-based guidance for the safe use of contraceptive methods among U.S. women with certain characteristics or medical conditions (1). The U.S. MEC is adapted f...

Dec 20th, 2019 - Vaginitis is defined as inflammation or infection of the vagina and is associated with a spectrum of symptoms, including vulvovaginal itching, burning, irritation, dyspareunia, "fishy" vaginal odor, and abnormal vaginal discharge. Vaginal symptoms...

May 7th, 2020 - Background: Adoptive cell therapy (ACT) using autologous tumor infiltrating lymphocytes can mediate the regression of bulky metastatic melanoma when administered along with high-dose aldesleukin (IL-2) following a non-myeloablative lymphodepleting...

May 5th, 2020 - PRIMARY OBJECTIVES: I. To assess the safety and tolerability of ibrutinib and rituximab (R)-dose adjusted (da)-etoposide, prednisone, vincristine sulfate, cyclophosphamide, and doxorubicin hydrochloride (EPOCH) in participants with acquired immuno...

May 5th, 2020 - PRIMARY OBJECTIVES: I. To demonstrate safety and feasibility of ipilimumab and nivolumab at the standard doses of drug in solid tumor and relapsed refractory HIV-classical Hodgkin lymphoma (cHL) participants with human immunodeficiency virus (HIV)...

May 5th, 2020 - Understanding the rate of lymphocyte replication and destruction in HIV-infected patients, as well as the effects of therapy on lymphocyte replication should lead to a better understanding of the mechanisms behind the immunodeficiency induced by H...

May 5th, 2020 - The purpose of this protocol is to carry out laboratory studies concerning the immunopathogenesis of Common Variable Immunodeficiency (CVI) and related primary humoral immunodeficiency diseases. Additionally, we aim to document and track the progr...

Jun 24th, 2021 - Takeaway The ChAdOx1 nCoV-19 (AZD1222) vaccine given as a prime-boost regimen was well tolerated and produced similar immune responses in individuals with human immunodeficiency virus (HIV) well controlled on antiretroviral therapy (ART) vs those ...

May 11th, 2021 - A gene therapy that makes use of an unlikely helper, the AIDS virus, gave a working immune system to 48 babies and toddlers who were born without one, doctors reported Tuesday. Results show that all but two of the 50 children who were given the ex...

Jan 20th, 2021 - Human immunodeficiency virus (HIV) continues to be a major public health problem worldwide. At the end of 2019, an estimated 38 million individuals were living with HIV. Owing to gaps in HIV services, 1.7 million people were newly infected with HI...

Jan 5th, 2021 - The First Pandemic I vividly remember a malnourished young man whose blue-tinged lips and nail beds recalled a textbook picture of hypoxia. His chest CT scan revealed the "ground glass" opacity we recognized as incompatible with life. I hesitantly...

Jan 4th, 2021 - Adults with primary immunodeficiency (PID) and symptomatic secondary immunodeficiency (SID) are at risk of greater morbidity and mortality from COVID-19 compared with the general population, a new study suggests. The findings were published in the...